Underage alcohol use in youth with autism spectrum disorder

患有自闭症谱系障碍的青少年未成年人饮酒

• 批准号: 9978401
• 负责人: Emily F Rothman
• 金额: $ 25.93万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-15 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9978401
• 关键词: 20 year old; Address; Adolescent; Adult; Affect; Age; Agreement; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Award; Boston; Communication; Consequentialism; Data; Development; Diagnosis; Enrollment; Ensure; Equation; Evidence based intervention; Expectancy; Face; Factor Analysis; Feedback; Female; Frequencies; Future; Gender; Goals; Grant; Individual; Intellectual functioning disability; Intervention; Interview; Knowledge; Measures; Mediating; Medical center; Methods; Modeling; Motivation; Observational Study; Outcome; Parents; Participant; Patient Recruitments; Pattern; Perception; Population; Prevention program; Prevention strategy; Preventive Intervention; Provider; Psychometrics; Qualitative Methods; Research; Risk; Sampling; Scheme; Self Efficacy; Services; Structure; Substance Use Disorder; Surveys; Target Populations; Techniques; Testing; Time; Validity and Reliability; Youth; alcohol abstinence; alcohol expectancy; alcohol risk; alcohol use disorder; autism spectrum disorder; autistic children; cost effective; data format; design; drinking; experience; improved; informant; interest; male; parental monitoring; peer; prevent; programs; psychosocial; public health priorities; recruit; risk perception; service providers; theories; therapy development; underage drinking

Project Summary There are now approximately 450,000 youth with autism spectrum disorder (ASD) between the ages of 16-24 in the U.S., and 50,000 more turning 18 each year. The field is bracing for a surge in demand for services. Underage alcohol use is a priority public health problem and too little is known about underage alcohol use by youth with ASD. ASD may be protective against alcohol use in individuals with intellectual disability, but 44% of youth with ASD have average or high IQ, and some evidence suggests that these ASD youth may be at increased risk for alcohol use disorder as compared to neurotypical counterparts. Information about underage alcohol use in youth with ASD, and ultimately effective prevention strategies, are needed. The proposed research will achieve two specific aims. Aim 1 is to explore, using qualitative methods, underage alcohol use and non-use by youth with ASD and without ID, ages 16-20 years old. Half of these youth will have used alcohol in the past six months and half will not (N=40). A targeted enrollment scheme will ensure that research participants include males and females. Aim 1 interviews will explore topics that include motivations to use alcohol or abstain, alcohol expectancies, refusal self-efficacy, parental communication about alcohol, peer use norms, alcohol rule-following, and perception of risks; and in those with recent alcohol use, types of alcohol consumed, how procured, where it occurred, when, with whom and in what context, perceived effects, and consequences. Aim 1 interview participants will also give feedback on a draft survey, comprising multiple measures of alcohol-related constructs, in order to improve its face validity prior to implementation in Aim 2. Aim 2 will use the refined survey to quantitatively investigate underage alcohol use in a sample of ASD vs. demographically-matched neurotypical comparison subjects (N=190). Half will have used alcohol in the past six months, and half will have abstained. Psychometrics will be assessed including factor structure and internal reliability of scales. Next, structural equation techniques will be used to evaluate relationships of alcohol- related variables with alcohol use among neurotypical vs. ASD youth in order to test hypotheses and inform theory development. In addition to assessing relationships between variables. For Aim 2, a targeted enrollment scheme to ensure that research participants include males and females will also be used. Overall, a strength of the project is its Advisory Board, comprising youth with ASD, parents of youth with ASD, and service providers. For recruitment of participants with ASD, the research team will partner with a leading national non-profit that serves the population formerly referred to as having Asperger’s, or referred to as high functioning ASD, and the Boston Medical Center Autism Program. In the long-term, the ultimate goal of this line of research is generalizable knowledge about underage alcohol use in U.S. youth with ASD and the development of evidence-based interventions to prevent it.

项目摘要 现在大约有450,000名自闭症谱系障碍（ASD）的年龄在16-24岁之间 在美国，每年有50,000次年满18岁。该领域正在为服务需求激增。 未成年饮酒是优先的公共卫生问题，对未成年人饮酒知之甚少 ASD的青年。 ASD可能会受到智障人士的饮酒的保护，但有44％ ASD的青年有平均或高智商，一些证据表明这些ASD青年可能处于 与神经型对应物相比，饮酒障碍的风险增加。有关未成年人的信息 需要使用ASD的青年饮酒，并且需要最终有效的预防策略。提议 研究将实现两个具体目标。 AIM 1是使用定性方法探索饮酒 ASD和没有ID的青年不使用16-20岁的年龄。这些年轻的一半会使用 在过去的六个月中，酒精不会（n = 40）。有针对性的入学计划将确保研究 参与者包括男性和女性。 AIM 1访谈将探索包括使用动机的主题 酒精或戒酒，酒精期望，拒绝自我效能，父母关于酒精的交流，同伴使用 规范，酒精规则的遵守和风险感知；在最近使用酒精的人中，酒精类型 消费，如何采购，发生的地方，何时，与谁以及在什么情况下，感知效果以及 结果。 AIM 1面试参与者还将对草稿进行反馈，完成多个 为了在AIM 2实施之前，与酒精相关结构的衡量标准以提高其面部有效性。 AIM 2将使用精致的调查来定量研究ASD VS样本中的未成年酒精使用。 人口统计学匹配的神经型比较主题（n = 190）。过去一半会用酒精 六个月，一半将弃权。将评估心理计量学，包括因素结构和内部 量表的可靠性。接下来，结构方程技术将用于评估酒精的关系 神经型与ASD青年之间使用酒精使用的相关变量，以检验假设并告知 理论发展。除了评估变量之间的关系。对于目标2（目标2） 还将使用研究参与者包括男性和女性的计划。总体而言， 该项目是其顾问委员会，使青年与ASD，ASD青年的父母和服务提供商一起完成。 为了通过ASD招募参与者，研究小组将与领先的国家非营利组织合作 服务于以前称为阿斯伯格的人口，或称为高功能ASD， 波士顿医疗中心自闭症计划。从长远来看，这一研究的最终目标是 关于ASD的美国青年和发展的知识 基于证据的干预措施以防止它。