The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve Health

俄勒冈州立大学临床和转化科学中心：推进当今的发现以改善健康

• 批准号: 9975951
• 负责人: REBECCA D JACKSON
• 金额: $ 449.71万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-29 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9975951
• 关键词: Address; Adopted; Adoption; Biomedical Research; Child Health; Childhood; Clinic; Clinical Sciences; Collaborations; Communities; Competence; Data; Data Analytics; Data Science; Development; Discipline; Education; Environment; Faculty; Foundations; Goals; Government; Grant; Health; Health system; Individual; Industry; Informatics; Information Dissemination; Institutes; Knowledge; Longevity; Methodology; Methods; Mission; Multi-Institutional Clinical Trial; Ohio; Participant; Pathway interactions; Patients; Pediatric Hospitals; Population; Process; Publications; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Training; Resources; Role; Science; Scientist; Secure; System; Time; Training; Training Programs; Training Support; Training and Education; Translational Research; Translations; Universities; Vision; Work; Workforce Development; base; career; career development; clinical center; college; data sharing; data to knowledge; education resources; improved; innovation; member; novel strategies; programs; research study; skill acquisition; tool; translational approach; translational pipeline

Contact PD/PI: Jackson, Rebecca D OVERVIEW SUMMARY Since our inception, the overarching mission of The Ohio State University’s Center for Clinical and Translational Science (CCTS) has been ambitious: to advance today’s discoveries to improve health. We do this by providing an integrated environment of clinical and translational science (CTS) resources, education, and training pathways and by promoting transformative methodologic advances to catalyze and sustain translational science innovation. In collaboration with our pediatric partner, Nationwide Children’s Hospital, we have developed an aligned vision for translational biomedical science that has been transformative. To continue with our mission, we propose to advance from catalyzing translational science innovation and team science locally to facilitating meaningful clinical and translational science collaborations with community, academic, industry, and government partners and with members of the CTSA Consortium. We will enhance and expand the training, career development, and sustainability of a diverse CTS workforce through the provision of comprehensive, accessible education resources and opportunities (Workforce Development) and engage a broad range of stakeholders as partners in the full spectrum of translational research as active team participants from study inception through dissemination of results (Collaboration and Engagement). We will provide new approaches and resources to enhance inclusion of populations that have traditionally been excluded or studied in isolation and support and enhance studies that span the translational research spectrum by actively reducing barriers to research study participation and catalyzing the translation of discoveries to the clinic and population and across the lifespan (Integration). Moreover, we will promote innovation, quality, and efficiency to advance translational science through an integrated system of translational research resources (Methods and Processes). Finally, we will embed informatics and data analytic solutions across all programs in the OSU-CCTS and across the full spectrum of translational research (Informatics) by integrating and interrogating research data within a secure data environment, develop and adopt innovative methods and tools that facilitate research, and provide a critical foundation in data sciences for the translational science workforce. Over the next 5 years, we will provide a robust research infrastructure and comprehensive research training programs informed by local innovations and strengthened by the adoption of best practices identified by the CTSA Consortium. By leveraging our interdisciplinary scientific strengths, expertise, and perspectives, the OSU-CCTS will catalyze biomedical research translation. With a commitment to experimentation, we will identify gaps and challenges, systematically develop and study (demonstrate) new methods and approaches, and disseminate effective strategies and educational initiatives that will transform clinical and translational science both locally and nationally. Project Summary/Abstract Page 275 Contact PD/PI: Jackson, Rebecca D

联系PD/PI：杰克逊，丽贝卡D 概述 概括 自成立以来，俄亥俄州立大学临床中心的总体任务和 转化科学（CCT）是雄心勃勃的：促进当今的发现以改善健康。我们 通过提供临床和转化科学（CTS）资源，教育，教育的综合环境来执行此操作 和培训途径，并通过促进变革性的方法学进步来催化和维持 翻译科学创新。与我们的儿科伴侣，全国儿童医院合作，我们 已经为翻译的生物医学科学发展了一致的愿景。到 继续我们的使命，我们建议从催化翻译科学创新和团队中脱颖而出 本地科学促进有意义的临床和转化科学合作 社区，学术，工业和政府合作伙伴以及与CTSA财团的成员。 我们将增强和扩大潜水员CTS劳动力的培训，职业发展和可持续性 通过提供全面，可访问的教育资源和机会（劳动力 开发）并参与各种转化范围的合作伙伴的广泛利益相关者 通过传播结果（协作和 订婚）。我们将提供新的方法和资源，以加强包含有 传统上被排除或研究以孤立和支持并增强跨越翻译的研究 通过积极减少研究研究参与的障碍并催化翻译的研究范围 发现诊所和人口以及整个生命周期（整合）的发现。而且，我们将促进 创新，质量和效率，通过集成系统 翻译研究资源（方法和过程）。最后，我们将嵌入信息和数据 OSU-CCT和整个转化研究范围的所有程序的分析解决方案 （信息学）通过在安全的数据环境，开发和 采用促进研究的创新方法和工具，并为数据科学提供关键的基础 对于翻译科学劳动力。在接下来的5年中，我们将提供强大的研究基础设施 以及由当地创新告知的全面研究培训计划，并由 采用CTSA财团确定的最佳实践。通过利用我们的跨学科科学 优势，专业知识和观点，OSU-CCT将催化生物医学研究翻译。与 对实验的承诺，我们将确定差距和挑战，系统地发展和研究 （演示）新方法和方法，并传播有效的策略和教育计划 这将改变本地和全国的临床和翻译科学。 项目摘要/摘要页面275 联系PD/PI：杰克逊，丽贝卡D