Simultaneous Alcohol and Marijuana Use: Momentary Influences and Consequences

同时使用酒精和大麻：暂时的影响和后果

• 批准号: 9927543
• 负责人: Ashley Nicole Linden-Carmichael
• 金额: $ 16.52万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-10 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9927543
• 关键词: Acute; Address; Affect; Alcohol abuse; Alcohol consumption; Alcohol or Other Drugs use; Alcoholic Intoxication; Alcohols; Applications Grants; Award; Behavior; Behavioral; Complex; Data; Data Analyses; Data Analytics; Development; Development Plans; Ecological momentary assessment; Ethnic Origin; Event; Exhibits; Generations; Goals; Grant; Greek; Heavy Drinking; Heterogeneity; Impairment; Individual; Institution; Intervention; Intoxication; Knowledge; Laws; Leadership; Legal; Life; Light; Link; Longevity; Marijuana; Measures; Medical Marijuana; Mental Health; Mentored Research Scientist Development Award; Mentors; Mentorship; Methodology; Methods; Motivation; National Research Service Awards; Odds Ratio; Outcome; Paper; Participant; Pattern; Pennsylvania; Perception; Persons; Population; Prevention Research; Process; Public Health; Race; Reporting; Research; Research Activity; Research Personnel; Resources; Risk; Risk Factors; Sampling; Speed; Surveys; Techniques; Technology; Tilia; Time; Training; Training Activity; Universities; Vehicle crash; Work; alcohol use disorder; base; behavioral health; career; career development; drinking; drinking behavior; driving behavior; experience; follow-up; high risk; high risk drinking; innovation; innovative technologies; marijuana use; marijuana use disorder; marijuana user; novel; pre-doctoral; programs; sensor; sex; skills; social; statistics; university student; unsafe driving; young adult; young adult alcohol use

Project Summary/Abstract The research plans and tailored training activities proposed in this Mentored Research Scientist Development Award (K01) application will enable the Candidate, Dr. Ashley N. Linden-Carmichael to develop essential skills to build her program of research and transition to independence as an alcohol investigator. Dr. Linden- Carmichael’s work uses innovative methodological and statistical techniques to gain an in-depth understanding of high-risk drinking patterns exhibited by young adults. The current application builds upon her previous work as a National Research Service Award (NRSA; F31) pre-doctoral fellow by studying an emerging public health concern: simultaneous alcohol and marijuana (SAM) use (i.e., using alcohol and marijuana at the same time). SAM use is particularly problematic because the use of both substances can interact to produce a synergistic effect on impairment. The proposed research activities aim to fill several gaps in our basic knowledge of SAM use by providing detailed, momentary information on the predictors and consequences of SAM use patterns through the innovative use of wearable alcohol sensors and ecological momentary assessments. Specifically, the two studies proposed aim to better understand SAM use patterns by (1) developing a brief measure of SAM use motives for use in ecological momentary assessment (EMA) surveys; (2) using EMA to identify person-, day-, and moment-level predictors of SAM use; (3) applying novel intensive longitudinal data methods to characterize dynamic features of alcohol intoxication within SAM and alcohol-only use episodes; and (4) comparing day-level consequences of episodes of SAM use versus use of either substance alone. This research will be conducted in The Edna Bennett Pierce Prevention Research Center at The Pennsylvania State University, an ideal and thriving research institution that will provide the Candidate with all of the resources she needs to carry out her research agenda and training goals. The Candidate will be mentored by an interdisciplinary team of experts with unique and overlapping skillsets: Dr. Stephanie Lanza (expert in intensive longitudinal data analysis), Dr. Jennifer Maggs (expert in theoretical frameworks for substance use across the lifespan), Dr. Joshua Smyth (expert in EMA methodology), and Dr. Emily Ansell (expert in momentary marijuana assessment). The career development plan outlined in this K01 application will allow the Candidate to obtain essential training on (1) problematic substance use behavior among young adults, (2) assessing high-risk drinking behavior and its correlates in the moment, (3) analyzing complex intensive longitudinal data, and (4) producing high-impact papers and successful grant applications to advance leadership in co-use. The research plan and training activities will facilitate Dr. Linden-Carmichael’s long-term career goal of building an independent program of research focused on understanding and intervening on problematic substance co-use patterns among young adult drinkers.

项目摘要/摘要 研究计划和量身定制的培训活动在这项指导的研究科学家发展中提出 奖项（K01）申请将使候选人Ashley N. Linden-Carmichael博士能够发展基本技能 为了建立她的研究和过渡计划，成为一名酒精调查员。林登博士 Carmichael的工作使用创新的方法论和统计技术来获得深入的理解 年轻人暴露的高风险饮酒方式。当前的申请基于她以前的工作 作为国家研究服务奖（NRSA； F31），通过研究新兴公共卫生 问题：简单的酒精和大麻（SAM）使用（即同时使用酒精和大麻）。 SAM使用特别有问题，因为两种物质的使用都可以相互作用以产生协同作用 对损害的影响。拟议的研究活动旨在填补我们对SAM的基本知识的几个空白 通过提供有关SAM使用模式的预测因素和后果的详细，瞬间信息的使用 通过创新使用可穿戴酒精传感器和生态瞬时评估。具体来说， 两项研究旨在更好地了解SAM使用模式，通过（1）制定简要测量 Sam在生态瞬时评估（EMA）调查中使用动机； （2）使用EMA识别 SAM使用的人，日间和力矩级别的预测指标； （3）应用新颖的密集纵向数据方法 表征SAM中酒精毒性的动态特征，仅使用酒精的发作； （4） 比较单独使用两种物质的SAM使用的日期后果。这 研究将在宾夕法尼亚州的Edna Bennett Pierce预防研究中心进行 州立大学是一家理想且蓬勃发展的研究机构，将为候选人提供所有 她需要进行研究议程和培训目标。候选人将由 具有独特和重叠技能​​的专家跨学科团队：Stephanie Lanza博士（专家 密集的纵向数据分析），Jennifer Maggs博士（理论框架的专家 在整个生命周期中），Joshua Smyth博士（EMA方法论专家）和Emily Ansell博士（专家 暂时的大麻评估）。本K01应用程序中概述的职业发展计划将允许 候选人获得有关（1）年轻人中有问题的物质使用行为的基本培训，（2） 评估高风险饮酒行为及其相关时刻，（3）分析复杂密集型 纵向数据，以及（4）生产高影响力的论文和成功的赠款申请以推进 共同利用的领导。研究计划和培训活动将有助于Linden-Carmichael博士的长期 建立独立研究计划的职业目标，专注于理解和介入 年轻成人饮酒者中有问题的物质共同使用模式。