CCTN - CLINICAL EVALUATION OF LONG ACTING REVERSIBLE CONTRACEPTIVES

CCTN - 长效可逆避孕药的临床评估

基本信息

批准号：
9915350
负责人：
ALISON EDELMAN
金额：
$ 6.97万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-25 至 2020-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9915350
关键词：
Age Attitude Chlamydia Clinical Practice Guideline Clinical Trials Network Contraceptive Agents Contraceptive History Contraceptive methods Copper Intrauterine Devices Counseling Data Data Analyses Development Devices Eligibility Determination Enrollment Excision Future Gonorrhea Good Clinical Practice Guidelines Gynecology Hemorrhage Hormones Incidence Informed Consent International Intrauterine Devices Lead Medical Menstrual cycle Methods Muscle Cramp National Institute of Child Health and Human Development Pain Pap smear Pattern Phase Pregnancy Pregnancy Tests Preparation Procedures Protocols documentation Randomized Randomized Controlled Clinical Trials Recording of previous events Records Recovery Regulation Reproductive History Risk Risk Factors Safety Sampling Site Specific qualifier value Testing Thromboembolism Ultrasonography Urine Venous Visit Woman birth control contraceptive effectiveness contraceptive efficacy demographics effectiveness trial follow-up medically necessary care novel prospective protocol development recruit reproductive research clinical testing reversible contraceptive screening side effect standard of care symposium treatment arm trial design

项目摘要

To evaluate contraceptive efficacy, pain of insertion, bleeding patterns, associate cramping, expulsion rates as well as other safety and side effects of the long acting reversible contraceptive (LARCs) in women of reproductive age. The Contraceptive Discovery and Development Branch (CDDB) under the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is committed to develop new methods that are long acting reversible contraceptives that can provide safe and effective contraception for women who may have risk factors against some contraceptive products as well as reduce the risk of venous thromboembolism (VTE). The copper intrauterine devices (IUDs) are example of intrauterine systems that provide long acting contraceptive benefits without exogenous hormones or disruption of the regular menstrual cycle.

旨在评估育龄妇女长效可逆避孕药 (LARC) 的避孕效果、插入疼痛、出血模式、相关痉挛、排出率以及其他安全性和副作用。尤尼斯·肯尼迪·施赖弗国家儿童健康和人类发展研究所 (NICHD) 下的避孕药发现和开发分部 (CDDB) 致力于开发长效可逆避孕药新方法，为可能面临风险的女性提供安全有效的避孕方法一些避孕产品的不利因素以及降低静脉血栓栓塞 (VTE) 的风险。铜宫内节育器 (IUD) 是宫内系统的一个例子，它可以提供长效避孕效果，且无需外源激素或破坏正常的月经周期。