Consequences of Substance Use on the Development of Impulse Control

物质使用对冲动控制发展的影响

• 批准号: 9913478
• 负责人: Donald M Dougherty
• 金额: $ 65.43万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-15 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9913478
• 关键词: 12 year old; Address; Adolescence; Adolescent; Adolescent Development; Adolescent Risk Behavior; Adolescent and Young Adult; Affect; Age; Alcohol or Other Drugs use; Automobile Driving; Behavior; Behavioral; Biological Models; Caregivers; Characteristics; Child; Communities; Complex; Development; Developmental Process; Environment; Environmental Risk Factor; Esthesia; Event; Family; Family history of; Funding; Goals; Growth; Impulsive Behavior; Impulsivity; Individual; Individual Differences; Interview; Knowledge; Laboratories; Lead; Life; Measures; Modeling; Monitor; National Institute of Drug Abuse; National Institute of Mental Health; Outcome; Parents; Patient Self-Report; Pattern; Prevention program; Process; Recording of previous events; Reporting; Research; Risk; Risk-Taking; Sampling; Severities; Strategic Planning; Substance Use Disorder; Testing; United States National Institutes of Health; Work; Youth; behavior measurement; cohort; contextual factors; design; disorder control; early onset; early onset substance use; emerging adult; environmental stressor; experience; high risk; improved; peer; poriferasterol monoglucoside; preadolescence; recruit; resilience; social; social factors; substance use prevention; treatment program; young adult

Project Summary/Abstract This competing renewal of our longitudinal project proposes to elucidate mechanisms driving the initiation and progression of substance use is consistent with NIDA and NIMH's recently outlined strategic plans (NIDA, 2016; NIH CRAN, 2015; NIMH, 2015) prioritizing research on the period between adolescence and young adulthood. Defining features of typical adolescent development are increases in sensation seeking followed by more gradual increases in impulse control (described by the Dual Systems model). The discrepancy between developing sensation seeking and impulse control are theorized to result in risk-taking behaviors like substance use. In at-risk youth, these developmental processes may be further discrepant, which may be one mechanism for increased rates and severity of substance use involvement. The renewal project has been documenting the relationship of sensation seeking and impulse control since before substance use onset (10 to 12 years old at study entry), and this renewal will to continue to assess these processes and outcomes into young adulthood. More specifically, we will continue longitudinal assessments (every 6 months) of our at-risk (due to family history of substance use disorder) and control youth to monitor changes in substance use, impulse control, environmental, sensation seeking, risk and resiliency factors. Outcomes will be interpreted from the perspective of the Dual Systems model, and importantly, this work will extend this model by testing: (1) whether impulse control and sensation seeking develop independently from one another; (2) whether impulse control and sensation seeking development has additive or interactive effects on substance use involvement; (3) how the onset and escalation of substance use affects subsequent development of impulse control and sensation seeking; (4) how processes identified in the Dual Systems model develop among adolescents and young adults with family history risk; and (5) how social and environmental factors influence risk and resiliency for substance use and are interpreted in the context of the Dual Systems model. Interpreting these findings within the context of the Dual Systems model will help to refine and extend the key premises of this model, as well as reveal more detail about developmental mechanisms of substance use involvement.

项目摘要/摘要 我们纵向项目的这种竞争更新提议阐明推动启动的机制 NIDA和NIMH最近概述的战略计划（NIDA，NIDA， 2016; NIH Cran，2015年； NIMH，2015）优先考虑对青春期和年轻之间的期间的研究 成年。定义典型青少年发展的特征是寻求感觉的增加，然后是 冲动控制的逐渐增加（由双重系统模型描述）。之间的差异 理论上将寻求和冲动控制的感觉寻求和冲动控制构成了冒险行为 使用物质。在高危的青年中，这些发展过程可能会进一步差异，这可能是一个 提高物质使用介入率和严重程度的机制。更新项目已经 自从使用物质使用之前，记录寻求和冲动控制的感觉的关系（10 到12岁的研究入学），这种续约将继续评估这些过程和结果 年轻成年。更具体地说，我们将继续对处于风险的纵向评估（每6个月） （由于药物使用障碍的家族病史）和控制青年以监测药物使用的变化， 冲动控制，环境，感觉寻求，风险和弹性因素。结果将被解释 从双重系统模型的角度来看，重要的是，这项工作将通过测试扩展此模型： （1）寻求冲动控制和感觉寻求彼此独立发展； （2）是否 脉冲控制和感觉寻求开发对物质的使用具有加性或交互作用 参与； （3）物质使用的发作和升级如何影响随后的冲动发展 控制和感觉寻求； （4）双重系统模型中确定的过程如何发展 有家族史风险的青少年和年轻人； （5）社会和环境因素如何影响 对物质使用的风险和弹性，并在双系统模型的背景下进行解释。 在双重系统模型的背景下解释这些发现将有助于完善和扩展关键 该模型的前提，并揭示有关物质使用的发展机制的更多详细信息 参与。