The Rapid-Production of the High-Performance and Affordable Cadmium Telluride and Cadmium Zinc Telluride for Medical Imaging Applications

快速生产用于医学成像应用的高性能且经济实惠的碲化镉和碲化镉锌

• 批准号: 9908694
• 负责人: John S McCloy
• 金额: $ 14.69万
• 依托单位: RADIATION DETECTION TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-19 至 2021-06-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9908694
• 关键词: Businesses; Caliber; CdZnTe; Crystallization; Densitometry; Dental; Detection; Devices; Diagnostic Imaging; Diagnostic radiologic examination; Discipline of Nuclear Medicine; Fruit; Gamma Rays; Goals; Government; Grain; Growth; Harvest; High temperature of physical object; Hour; Image; Industrialization; Industry; Medical; Medical Imaging; Methods; National Security; Outcome; Performance; Phase; Positron-Emission Tomography; Price; Process; Production; Property; Radiation; Research; Resolution; Roentgen Rays; Rotation; Security; Techniques; Technology; Temperature; Time; Travel; United States; Universities; Washington; base; bone; cadmium telluride; commercialization; cost; crystallinity; detector; improved; instrumentation; melting; new growth; oncology; radiation detector; scale up; single photon emission computed tomography

1 The high spatial-resolution and energy-resolution of cadmium zinc telluride (CZT) and cadmium telluride 2 (CdTe), compared to that of scintillators, offers superior image quality in Nuclear medicine and X-ray 3 imaging applications, i.e. SPECT, PET, CT, Bone Densitometry, Oncology, Dental imaging, Airport 4 security, etc. Even after two decades of research, CZT and CdTe remain the desired choice for room- 5 temperature radiation detection, but it is limited by high-cost and availability resulting from low yield and 6 long production times associated with commercial growth techniques, i.e. the Traveling Heater Method 7 (THM). However, the application of the Accelerated Crucible Rotation Technique by Modified Vertical 8 Bridgman (ACRT-MVB) growth method at WSU has proven to produce industrial quality, high- 9 performance CZT/CdTe. This new growth method not only allows CZT/CdTe to be grown with the same 10 quality as material grown by THM, but also at growth rates approximately 10-20 times faster than THM. 11 Specifically, CZT/CdTe is grown by THM at a rate of approximately 1-3 mm per day, whereas CZT/CdTe 12 growth by ACRT-MVB can be accomplished at much faster rates of approximately 1-2 mm per hour. 13 CZT/CdTe crystal growth in the current commercial methods, the Traveler Heater Method (THM), requires 14 a lower growth temperature for high-quality devices, which results in highly off-stoichiometric melts, 15 thereby inducing the need for postprocessing. These major challenges associated with the crystal growth of 16 CZT/CdTe have been overcome using ACRT-MVB. Improving and reproducing the single-crystal yield of 17 commercial grade CZT/CdTe is the next critical step. Recently, considerable improvement in the single- 18 crystal yield has been achieved by WSU when grown under off-stoichiometric (3.5%-5% excess Te) 19 conditions. An optimization in terms of rotation profile, temperature profile, and Te concentration will be 20 performed to improve the yield while retaining the superior device performance in Phase I efforts. In Phase 21 II, this technology will be transferred from WSU to RDT. The medical/diagnostic imaging market is 22 projected to cross $55.7 billion by 2025. Stakeholders in the medical imaging market need CZT/CdTe 23 devices now, especially devices that are capable of high count-rate imaging applications – a focus in this 24 Phase I effort. The fruition of this project will be the significant reduction (>3x) of industrial-grade material 25 costs by increasing the yield, reducing the growth time, and eliminating post-growth anneal treatments 26 currently used by industry. With the fast-production time and high-performance of the CZT/CdTe produced 27 in this effort, (1) the medical imaging market will finally have a fast turnaround time and consistent high- 28 performance material that can easily be obtained, (2) a >3x price reduction is projected for CZT/CdTe, and 29 (3) US business will have access to an affordable, high-performance CZT/CdTe material that can be 30 obtained for imaging instrumentation and other radiation detection applications.

1镉卸尿酸锌（CZT）和牙也牙杜以分辨率的高空间分辨率和能量分辨率 2（CDTE），与闪烁体相比，核医学和X射线的图像质量卓越 3个成像应用，即SPECT，PET，CT，骨密度测定法，肿瘤学，牙科成像，机场 4安全等。即使经过二十年的研究，CZT和CDTE仍然是房间的理想选择 5温度辐射检测，但受到低收率和可用性的限制 6个与商业增长技术相关的长期生产时间，即行进加热器方法 7（THM）。但是，通过修改的垂直进行加速坩埚旋转技术的应用 8 WSU的Bridgman（ACRT-MVB）增长方法已证明可以产生工业质量，高 9性能CZT/CDTE。这种新的增长方法不仅允许CZT/CDTE与相同的生长 10质量作为THM生长的材料，但增长率也比THM快10-20倍。 11具体，CZT/CDTE以每天约1-3毫米的速率生长，而CZT/CDTE 12通过ACRT-MVB增长的速度约为每小时1-2毫米。 13 CZT/CDTE晶体生长在当前商业方法中，旅行者加热器方法（THM）需要 14高质量设备的较低生长温度，从而导致高度底漆熔体， 15因此，引起了后处理的需求。这些与晶体生长有关的主要挑战 16 CZT/CDTE使用ACRT-MVB已经克服了。改善和再现单晶产量 17商业级CZT/CDTE是下一个关键步骤。最近，单一的改善 WSU在非化学计量学下生长（3.5％-5％超过TE）已实现18个晶体产量 19条件。旋转曲线，温度轮廓和TE浓度的优化将是 20旨在提高产量，同时在第一阶段的工作中保留了出色的设备性能。在阶段 21 II，该技术将从WSU转移到RDT。医疗/诊断成像市场是 22预计到2025年将超过557亿美元。医学成像市场中的利益相关者需要CZT/CDTE 现在有23个设备，尤其是能够具有高计数速率成像应用的设备 - 重点是 24第一阶段的努力。该项目的流量将是工业级材料的显着减少（> 3倍） 25成本通过增加产量，减少增长时间并消除增长后退火治疗 26目前由行业使用。随着CZT/CDTE的快速生产时间和高性能 27在这项工作中，（1）医学成像市场最终将有一个快速的周转时间和一致的高度 - 28可以轻松获得的性能材料，（2）预计CZT/CDTE的价格降低> 3倍，并且 29（3）美国业务将可以使用可承受的高性能CZT/CDTE材料 30用于成像仪器和其他辐射检测应用。