The Importance of Place in Determining Health and Mortality at Older Ages

地点在决定老年人健康和死亡率方面的重要性

• 批准号: 9766176
• 负责人: Jason Michael Fletcher
• 金额: $ 39.42万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9766176
• 关键词: 3-Dimensional; Adult; Affect; Age; American; Atlases; Attention; Basic Science; Biology; Birth; Birth Place; Cessation of life; Childhood; County; Data; Data Set; Deceleration; Demography; Diabetes Mellitus; Disadvantaged; Disease; Economics; Education; Elderly; Environment; Epidemiology; Ethnic Origin; Exposure to; Geography; Health; Health and Retirement Study; Individual; Industry; Inequality; Infant Mortality; Knowledge; Left; Life; Life Cycle Stages; Life Expectancy; Life Tables; Link; Literature; Longevity; Longitudinal Studies; Measures; Morbidity - disease rate; Native-Born; Obesity; Outcome; Pathway interactions; Pattern; Policies; Population; Process; Race; Research; Residential Mobility; Respondent; Shapes; Social stratification; Source; Surveys; System; Techniques; Time; Time trend; Variant; Vital Statistics; Wisconsin; Work; base; cohort; contextual factors; deprivation; disability; early life exposure; econometrics; experience; health disparity; health inequalities; insight; mortality; novel; population health; response; rurality; sex; social; socioeconomics; trend

UProject Summary Title: The Importance of Place of Birth in Determining Health and Mortality at Older Ages Substantial spatial inequalities in old age health and mortality outcomes are well documented. Previous studies have linked old age health to contemporaneous spatial context. However, by old age, over a third of the popu- lation has left their state of birth and an even greater share has left their county of birth, leaving the interpreta- tion of contemptuous links between geography and health clouded by endogenous mobility and disregarding the importance of childhood exposures in producing the spatial inequalities in health across the life course and into old age. Successfully unraveling the importance of life course exposures and decisions producing old age spatial inequalities has the potential to contribute to basic science as well as policy, but efforts have been ham- pered by a lack of large datasets with place of birth information. Our proposal takes advantage of newly avail- able data on place of birth for over 5 million Americans born across the early to mid 20PthP century combined with our team's interdisciplinary background merging the demography, economics, population health, and epidemi- ology of old age morbidity and mortality processes. UOur overall aim is to uncover the extent to which place of birth has contributed to old age health inequalities by birth cohort, race/ethnicity, sex, and educa- tional attainment in the US, and to explore the mechanisms underlying these relationshipsU. Our re- search team will leverage newly released and unique longitudinal data on millions of individuals across multiple datasets containing rich measures of health processes in old age and mechanisms of early disease exposures, cumulative contextual disadvantage, and life course mobility. Using these data, we will Upursue the following aimsU: (1) Aim 1: Create an “Atlas of Birth Place Impacts on Mortality and Morbidity at Older Ages”, (2) Deter- mine the Influence of Birth Place on Health Disparities and Mortality Variation at Older Ages by sex, race/eth- nicity, and education and (3) Uncover mechanisms linking the relationship between place of birth and later health by focusing on mobility and early and cumulative exposures. Together, these aims will allow a paradigm shift in how we understand old age health processes by integrating life course and spatial analysis into large scale analyses of the patterns and mechanisms of old age health and mortality.

UPROROTION摘要 标题：出生地点在确定老年健康和死亡率方面的重要性 老年健康和死亡率的大量空间不平等现象已得到充分的证明。先前的研究 已经将老年健康与当代空间环境联系起来。但是，到老年，超过三分之一的popu- Lays离开了出生状态，更大的份额离开了他们的出生县，离开了解释 - 地理与健康之间的鄙视联系，内源性流动性和无视 童年暴露在生命过程中产生健康空间不平等方面的重要性 进入老年。成功地揭示生命过程的重要性曝光和决定产生了老年 空间不平等有可能为基础科学和政策做出贡献，但努力一直是 由于缺乏大型数据集而缺乏出生地信息。我们的建议利用新近可用的优势 - 超过500万美国人在20pthp世纪初出生的超过500万美国人的能力数据与 我们团队的跨学科背景融合了欺骗，经济学，人口健康和流行 老年发病率和死亡率过程的神学。整体目标是揭示哪个地方的程度 通过出生队列，种族/种族，性别和教育，出生的出生促成了老年健康的不平等现象。 在美国的实现成就，并探索这些关系的基础机制。我们的重新 搜索团队将利用新发布的新发布和独特的纵向数据，以了解数百万个人 包含老年健康过程和早期疾病暴露机制的健康过程的数据集， 累积上下文灾难和生命课程流动性。使用这些数据，我们将为以下 AIMSU：（1）AIM 1：创建“出生地的地图集对老年时代的死亡率和发病率的影响”，（2） 在性别，种族/eth- 善良和教育以及（3）发现与出生地点之间关系联系起来的机制 通过关注流动性以及早期和累积暴露。这些目标在一起将允许范式 通过将生活课程和空间分析整合到大型的情况下，我们如何理解老年健康过程 对老年健康和死亡率的模式和机制的规模分析。