Molecular Helminthology: An Integrated Approach

分子蠕虫学：综合方法

基本信息

批准号：
9763186
负责人：
Philip T LoVerde
金额：
$ 0.65万
依托单位：
UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-03-01 至 2020-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9763186
关键词：
Academia Address Affect Animals Area Biochemistry Biological Biological Markers Biology Biotechnology CRISPR/Cas technology Cells Centers for Disease Control and Prevention (U.S.)Cestoda Child Development Country Development Discipline Disease Drug Targeting Drug effect disorder Drug resistance Endemic Diseases Feedback Fruit Future Gene Expression Gene Transfer Genes Goals Government Health Helminth Genes Helminths Human Immunologist Industry Knock-out Knowledge Molecular Parasites Parasitic nematode Participant Postdoctoral Fellow Poverty Productivity Public Health RNA Interference Regimen Renaissance Research Research Personnel Schistosoma Scientist Signal Pathway Students Time Translating Underrepresented Minority United States National Institutes of Health Woman Work World Health Organization design experience girls helminth genetics helminth infection immunoregulation improved interest meetings metabolome microbiome multidisciplinary neglected tropical diseases novel peer posters programs symposium tool vector

项目摘要

Abstract Molecular Helminthology: An Integrated Approach” has the goal of bringing researchers up-to-date with advances in the field, demonstrate the ability to ask cutting edge questions by using the newly available research tool box, and give young scientists a chance to present their work and see the future directions of the discipline. The conference is designed not just to present the recent findings in the field of molecular helminthology but also to take advantage of the remarkable advances anticipated and occurring in the field. A renaissance of approaches including all aspects of `omics' as well as novel molecular tools, such as gene transfers, gene knock-outs, RNA interference and CRISPR-CAS9 is now available. These approaches have led to novel hypotheses and questions that will underpin the topics for this unique conference. The task is to integrate the rapidly accumulating knowledge from parasitic helminths and to translate that information into relevant directions in the study of their unique biology and host- helminth interactions. This multidisciplinary conference will bring together scientists from many research perspectives. Proposed topics are listed below. The importance of this symposium is that it highlights research on helminth parasites, which is critically underrepresented. This timely conference is geared to inspire the early-stage scientists who will set the direction for the future. Our primary goal is to invite speakers who will present cutting edge research on helminths. The end result will be a toolbox for helminth research that has improved dramatically since the last meeting to resolve novel questions of the biology of helminths and helminth-host interactions. A secondary goal is to encourage everyone especially the junior people to network. A special effort will be made to make sure that the students/postdocs and disease endemic scientists meet with the speakers of interest. Another goal is to assure that we are inclusive as far as diversity and underrepresented minorities are concerned. Themes:  Interrogating Helminth `omics  Helminth - Host interplay; immunomodulation, microbiome and metabolome  Tools to Manipulate Helminth Gene Expression  Signaling Pathways and Biomarkers in Helminths  Genetics and Biochemistry of Drug Targets, Drug Action and Resistance

抽象的分子掌舵方法：一种综合方法”的目的是使研究人员带来随着现场进步的最新状态，展示了询问最前沿的能力通过使用新可用的研究工具箱来解决问题，并为年轻科学家提供一个有机会介绍他们的作品并查看该学科的未来方向。该会议的设计不仅是为了介绍该领域的最新发现分子掌舵术，但也利用了显着的进步预期并发生在现场。包括所有方面的方法的复兴 “ omics”以及新型分子工具，例如基因转移，基因敲除， RNA干扰和CRISPR-CAS9现在可用。这些方法已导致新颖的假设和问题将为这次独特的会议介绍主题。任务是整合来自寄生虫的快速积累的知识并将这些信息转化为研究其独特的方向生物学和宿主 - 蠕虫相互作用。这个多学科会议将使许多研究的科学家聚集在一起观点。建议的主题如下列出。该研讨会的重要性是它突出了对蠕虫寄生虫的研究，这份代表性不足。这次及时的会议旨在激发将设定的早期科学家未来的方向。我们的主要目标是邀请将介绍尖端研究的演讲者蠕虫。最终结果将是用于蠕虫研究的工具箱自上次会议以来，龙是龙请解决生物学的新颖问题蠕虫和蠕虫 - 主持人相互作用。次要目标是鼓励所有人尤其是初级人员网络。将要做出特别的努力来确保学生/博士后和疾病的内在科学家会见兴趣。另一个目标是确保我们在多样性方面具有包容性代表性不足的少数民族涉及。主题： 询问蠕虫 Helminth-主机相互作用；免疫调节，微生物组和代谢组 操纵蠕虫基因表达的工具 蠕虫中的信号通路和生物标志物 药物靶标，药物作用和抗药性的遗传学和生物化学