Injuries in Children with Autism

自闭症儿童受伤

基本信息

批准号：
9891178
负责人：
GUOHUA LI
金额：
$ 21.67万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-12-16 至 2021-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9891178
关键词：
20 year old 21 year old 8 year old Accident and Emergency department Accidental Injury Admission activity Age Aggressive behavior Attention Attention deficit hyperactivity disorder Behavior Behavioral Cessation of life Characteristics Child Child Welfare Childhood Childhood Injury Clinical Cognitive Data Data Reporting Data Set Databases Development Developmental Disabilities Diagnosis Diagnostic Drowning Educational process of instructing Emergency Department patient Emergency department visit Environment Epidemiology Executive Dysfunction General Population Geographic Locations Health Hospitalization Hospitals Impairment Injury Inpatients Intellectual functioning disability Intentional injury International Classification of Disease Codes International Classification of Diseases Laws Location Longevity Measures Morbidity - disease rate Nursery Schools Parents Patient Self-Report Patients Pattern Perception Population Population Group Prevalence Prevention strategy Preventive Intervention Procedures Reporting Research Risk Risk Factors Rural Safety Sample Size Sampling Self-Injurious Behavior Severities Social Interaction Source Suicide attempt Symptoms Time trend United States Visit Work aged assault autism spectrum disorder autistic children base comorbidity design early childhood effective intervention functional disability high risk population injury prevention interest mortality patient population payment pediatric emergency pediatric patients repetitive behavior sex social social communication surveillance data trauma centers trend

项目摘要

The long-term objective of the proposed project is to reduce injury morbidity and mortality in children with autism spectrum disorders (ASD). The specific aims are to: 1) examine the time trends of injuries treated in emergency departments (EDs) and hospitals among children with ASD aged 0–20 years; 2) characterize the epidemiologic patterns of injuries treated in EDs and hospitals among children with ASD according to age, sex, injury mechanism, intent and severity; and 3) assess the excess risks of injuries treated in EDs and hospitals associated with ASD. The estimated prevalence of ASD continues to rise. Surveillance data in the United States indicate that one in 59 children aged 8 years in 2014 met the diagnostic criteria for ASD and that one in 40 children aged 3 to 17 years had parent-reported ASD diagnosis. Injury has long been recognized as a major cause of morbidity and mortality in children in the United States, resulting in approximately 18,000 deaths with over 9 million emergency department visits and more than 200,000 hospitalizations among children younger than 20 years of age annually. Recent studies indicate that children with ASD may be at exceptionally heightened risk of injury mortality and certain types of injury morbidity, likely due to impairments in social, cognitive and behavioral functioning and common comorbid conditions such as attention deficit hyperactivity disorder and intellectual disability. Research on injury in children with ASD is inadequate and often limited by small sample sizes and self-reported data. Building on our recent work on injury mortality in children with ASD and injuries in preschool age children with ASD, the proposed project aims to close an important research gap by examining the time trends, epidemiologic patterns and excess risks of injuries treated in EDs and hospitals in children with ASD under 21 years of age based on nationally representative samples. We will use the Nationwide Emergency Department Sample for years 2009–2019 and the triennial Kids’ Inpatient Database from 1997 to 2019 to create datasets for pediatric ED patients with a diagnosis of ASD (n ≈ 300,000) and for pediatric inpatients with a diagnosis of ASD (n ≈ 70,000). We will examine the time trends, epidemiologic patterns and excess risks of injuries treated in EDs and hospitals among children with ASD according to injury mechanism, intent, severity, demographic characteristics, comorbid conditions, and geographic regions compared to the general pediatric patient population. Results from the proposed project will inform preventive strategies and facilitate the development of effective interventions to reduce injuries in children with ASD.

拟议项目的长期目标是减少患有儿童的伤害发病率和死亡率自闭症谱系障碍（ASD）。具体目的是：1）检查在 ASD年龄为0-20岁的儿童的紧急部门（EDS）和医院； 2）表征根据年龄，性别，性别，性行为儿童的EDS和医院治疗的流行病学模式伤害机制，意图和严重程度； 3）评估在ED和医院治疗的伤害的多余风险与ASD相关。 ASD的估计患病率继续上升。联合的监视数据各国表明，2014年89岁的59名儿童符合ASD的诊断标准，其中一个是 40名3至17岁的儿童已经对父母报告了ASD诊断。长期以来一直被认为是主要的美国儿童发病和死亡率的原因，大约有18,000人死亡年轻的儿童中有超过900万个急诊科和200,000多名住院每年超过20岁。最近的研究表明，患有ASD的儿童可能异常处于造成伤害死亡率的风险增加和某些类型的伤害发病率，可能是由于社会损害而导致的认知和行为功能以及常见的合并条件，例如注意力缺陷多动症混乱和智力障碍。关于ASD儿童受伤的研究不足，通常受到限制小样本量和自我报告的数据。基于我们最近关于ASD儿童伤害死亡率的工作拟议项目旨在缩小重要的研究差距通过检查时间趋势，流行病学模式并超过EDS和医院治疗的伤害风险根据全国代表性样本，在21岁以下的ASD儿童中。我们将使用全国急诊室样本2009 - 2019年和三年展的儿童住院数据库从1997年到2019年，为儿科ED患者创建数据集（诊断为ASD）（N≈300,000）和诊断为ASD（N≈70,000）的儿科住院患者。我们将检查时间趋势，流行病学模式，超过ASD儿童在EDS和医院受伤的伤害风险机制，意图，严重性，人口特征，合并状况和地理区域与一般儿科患者人群相比。拟议项目的结果将为预防性提供信息策略并促进开发有效的干预措施，以减少ASD儿童的伤害。