The 2019 Conference of the United States Human Proteome Organization (US HUPO)

2019年美国人类蛋白质组组织（US HUPO）会议

• 批准号: 9762425
• 负责人: STEVEN A CARR
• 金额: $ 1.3万
• 依托单位: PRINCETON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-02-19 至 2020-02-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762425
• 关键词: Address; Aging; American; Animal Model; Area; Attention; Bioinformatics; Biological; Biological Assay; Biology; Biomedical Research; Businesses; Cellular Assay; Chemical Structure; Child Care; Clinical; Clinical Research; Collaborations; Communicable Diseases; Complex; Country; Data Set; Development; Diagnosis; Disabled Persons; Discipline; Disease; District of Columbia; Early Diagnosis; Education; Educational workshop; Encapsulated; Ensure; Event; Experimental Designs; Exposure to; Eye; Faculty; Feedback; Fostering; Funding; Goals; Health; Hearing; Human; Human Biology; Immunity; Industrialization; Industry; Informatics; Institutes; International; Learning; Lightning; Malignant Neoplasms; Mass Spectrum Analysis; Measures; Medicine; Metabolism; Methodology; Minority; Minority Recruitment; Minority-Serving Institution; Mission; New York; Oral; Participant; Post-Translational Protein Processing; Post-Translational Regulation; Postdoctoral Fellow; Prevention; Proteins; Proteome; Proteomics; Published Comment; Research; Research Design; Research Personnel; Sampling; Scientist; Screening for cancer; Signal Transduction; Site; Societies; Structural Protein; Students; Technology; Thinking; Time; Training; Underrepresented Groups; Underrepresented Minority; United States; Universities; Woman; Work; assay development; bioinformatics tool; career; career development; clinical diagnostics; crosslink; diagnostic assay; early detection biomarkers; frontier; glycoproteomics; graduate student; human disease; improved; instrumentation; interest; meetings; microbiome; multidisciplinary; multiple omics; nervous system disorder; new technology; novel strategies; outcome forecast; posters; programs; protein structure; rapid growth; skills; social; symposium; technology development

PROJECT SUMMARY/ABSTRACT We request partial funding support for the Conference of the United States Human Proteome Organization (US HUPO) to be held at the Hilton Washington DC/Rockville Hotel & Executive Meeting Center in Bethesda/Rockville, MD on March 3-6, 2019. This meeting has established itself as a highly valued contribution to the interdisciplinary scientific field of proteomics, with a particular focus on current technologies in the field and their application to solving biological and clinical questions relevant to human health. The topics covered at the US HUPO conference reflect the multiple disciplines, strategies, and technologies encompassing the proteomics field, and their use to address complex biomedical problems and enable new discoveries aimed at advancing diagnosis, prognosis and treatment of human disease. The title of the conference, “Proteomics at the Frontiers of Biology and Medicine," encapsulates this interplay between technology (e.g. mass spectrometry, bioinformatics, clinical/cellular assays) and biological discovery inherent to the proteomics field. The 2019 conference co-organizers are Ileana Cristea (Princeton University), Steve Carr (Broad Institute), and David Fenyo (New York University). The topics of the oral sessions have been carefully selected to provide attendees exposure to the latest proteomic technologies and their application to biomedical research questions – in particular in the fields of cancer, infectious disease, immunity, microbiome, aging, and clinical diagnostics and assays. Oral presentation sessions with biological and clinical focus include: Glycoproteomics in Biology and Medicine, Infectious Diseases, Immunity and the Microbiome, Cancer Early Detection and Prevention, Metabolism and Disease, Protein Proteoforms in Health and Disease, Aging and Neurological Diseases, and Posttranslational Regulation and Signaling. Additionally, sessions dedicated to technology developments include Multi-Omics, Proteome Organization in Space and Time, Advances in Technology, Structural/Chemical Proteomics, and Informatics: Emerging/ New Approaches. Poster sessions will offer a less formal format for presentation and discussion of scientific topics. Organized social activities will provide opportunities for further discussion and collaborative networking between attendees. A Business Meeting will provide an open forum to hear about the mission of US HUPO and give feedback. Attendance is expected to be 350-400, including 100- 150 students/postdocs. A special effort will be made to recruit minority and industrial participants, and also provide a venue for young investigators to present their work – through mechanisms such as “lightning” talks. Funding requested through this R13 mechanism will help support minority and young investigator participation in the conference. Short courses and workshops will also be offered to either train attendees in advanced proteomic technologies or provide a forum for discussing career options and other timely scientific topics.

项目摘要/摘要 我们要求对美国人类蛋白质组组织（US）会议的部分资金支持 HUPO）将在希尔顿华盛顿特区/罗克维尔酒店与行政会议中心举行 2019年3月3日至6日，马里兰州贝塞斯达/罗克维尔。这次会议已成为高度重视的贡献 到蛋白质组学的跨学科科学领域，特别关注该领域的当前技术 以及他们在解决与人类健康有关的生物学和临床问题上的应用。涵盖的主题 美国HUPO会议反映了涵盖涵盖的多个学科，策略和技术 蛋白质组学领域及其用来解决复杂的生物医学问题并实现针对的新发现 推进人类疾病的诊断，预后和治疗。会议的标题，“蛋白质组学 生物学和医学的前沿，“封装了技术之间的相互作用（例如质谱， 生物信息学，临床/细胞分析）和蛋白质组学固有的生物学发现。 2019年 会议联合组织者是I​​leana Cristea（普林斯顿大学），史蒂夫·卡尔（Steve Carr）（广阔研究所）和大卫 Fenyo（纽约大学）。口头课程的主题已仔细选择以提供与会者 暴露于最新的蛋白质组学技术及其在生物医学研究问题上的应用 - 特别是在癌症，传染病，免疫学，微生物组，衰老和临床诊断的领域 测定。具有生物学和临床重点的口服演示会议包括：生物学和 医学，传染病，免疫和微生物组，癌症早期检测和预防， 代谢和疾病，健康和疾病中的蛋白质成型类成型，衰老和神经系统疾病以及 翻译后调节和信号传导。此外，专门针对技术发展的会议 包括多媒体，时空中的蛋白质组组织，技术进步，结构/化学 蛋白质组学和信息学：新兴/新方法。海报会议将为不太正式的格式提供 演讲和讨论科学主题。有组织的社交活动将为进一步提供机会 与会者之间的讨论和协作网络。商务会议将为开放论坛提供 听听我们的任务Hupo并提供反馈。预计出勤率为350-400，包括100- 150名学生/博士后。将为招募少数民族和工业参与者做出特别的努力，也将 通过诸如“闪电”谈话之类的机制，为年轻调查人员提供了一个供年轻调查人员展示其作品的场所。 通过这种R13机制要求的资金将有助于支持少数派和年轻研究者参与 在会议中。短课程和讲习班也将提供给高级培训与会者 蛋白质组学技术或提供讨论职业选择和其他科学主题的论坛。