3rd Symposium on Infectious Diseases in the Immunocompromised Host

第三届免疫低下宿主传染病研讨会

• 批准号: 9762550
• 负责人: MICHAEL J BOECKH
• 金额: $ 1.8万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-01 至 2020-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762550
• 关键词: Address; Adrenal Cortex Hormones; Adult; Affect; Area; Autoimmune Diseases; Autoimmune Process; Automobile Driving; Biological Response Modifier Therapy; Childhood; Clinical; Clostridium difficile; Communicable Diseases; Country; Cytomegalovirus; Dangerousness; Development; Disease; Elements; Environment; Event; Fostering; Fred Hutchinson Cancer Research Center; General Population; Goals; Immune System Diseases; Immunocompromised Host; Immunotherapy; Individual; Infection; Interdisciplinary Study; Knowledge; Life; Malignant Neoplasms; Mediating; Medical; Medical Students; Mentors; Modality; Morbidity - disease rate; Organ; Patient Care; Patients; Population; Prevention; Primary Infection; Research; Research Personnel; Resources; Savings; Science; Solid; Structure; Talents; Techniques; Time; Training; Training Programs; Training Support; Transplantation; Underrepresented Groups; Underrepresented Minority; United States; United States National Institutes of Health; Virus Diseases; Woman; antimicrobial; cancer therapy; career; clinical practice; experience; hematopoietic cell transplantation; immunosuppressed; improved; improved outcome; infection risk; innovation; interest; lectures; microbiome; mortality; novel; pathogen; pathogenic fungus; patient population; posters; prevent; programs; respiratory virus; response; skills; social group; success; symposium

PROJECT SUMMARY Within the United States, a growing proportion of the population is immunocompromised. Advances in transplantation techniques and cancer treatments, increased survival of these patients, and the development of novel agents to treat autoimmune diseases have contributed to the increase in this population. In the US, it is estimated that more than 340,000 people were living with a functioning transplanted solid organ (SOT) as of 2016, and over 56,000 new hematopoietic cell transplants and SOTs are done every year. Infection remains a major cause of morbidity and mortality for this highly susceptible population. Furthermore, these individuals are often affected by pathogens that rarely cause disease in healthy people. High-quality patient care and fostering collaborative, interdisciplinary research to increase our understanding of these infections, and drive development of new options for treatment and prevention, are vital priorities for improving outcomes among these patients. Conferences focused on infectious diseases specifically within immunocompromised patients are crucial for promoting timely discussions and efficient dissemination of ideas within the field, yet few such forums exist. To bridge this gap, the Fred Hutchinson Cancer Research Center's Infectious Disease Sciences Program launched in 2016 the Symposium on Infectious Diseases in the Immunocompromised Host. This event has attracted high-profile speakers and intense interest among those in the infectious diseases field, allowing us to expand the symposium to a two-day event with 176 attendees in the second year. Our 2019 symposium program will feature lectures by thought leaders in the field as well as early-career investigators, three keynote presentations, two interactive case discussions led by expert panels, and opportunities for trainees including presentations and two poster sessions. New topics addressed in our 2019 symposium program will include: Clostridium difficile, which disproportionately affects immunocompromised patients, and antimicrobial stewardship. Successful elements of our 2017 symposium will be maintained, including coverage of the following topics: Respiratory Virus Disease, Cytomegalovirus, Fungal Disease, Microbiome, and Immunotherapy. A distinct and innovative feature of this event is our focus on supporting attendance and participation by trainees, especially by women and individuals from underrepresented groups. We aim to continue this tradition by providing a generous number of trainee stipends and structuring our program to facilitate meaningful interactions between today's leaders in the field and the rising stars who will contribute to it for decades to come. We aim to foster productive discussions on infectious diseases in the immunocompromised host, driving progress on current issues in the field as well as promoting dissemination of knowledge that will improve clinical practice across the country. This conference strengthens the training pipeline by exposing early-career trainees to this enticing field, while supporting trainees (including those in our NIH-supported T32 training program) in honing their skills and gaining the visibility they need to launch independent careers.

项目摘要 在美国，越来越多的人口受到免疫功能低下。进步 移植技术和癌症治疗，这些患者的存活率增加以及发展 治疗自身免疫性疾病的新型药物有助于该人群的增加。在美国，是 据估计，截至 2016年，每年进行超过56,000个新的造血细胞移植和SOT。感染仍然是 高度易感人群的发病率和死亡率的主要原因。此外，这些人是 经常受到很少导致健康人疾病的病原体影响。高质量的患者护理和养育 协作，跨学科研究，以增加我们对这些感染的理解，并推动发展 在治疗和预防的新选择中，是改善这些患者预后的重要优先级。 专门针对免疫功能低下的患者中的传染病的会议至关重要 促进及时的讨论和在该领域内思想的有效传播，但很少有这样的论坛。 为了弥合这一差距，弗雷德·哈钦森癌症研究中心的传染病科学计划 于2016年启动了免疫功能低下的宿主中传染病研讨会。这个事件有 在传染病领域吸引了备受瞩目的演讲者和激烈的兴趣，使我们能够 第二年，将研讨会扩展到为期两天的活动中，有176名与会者。我们的2019研讨会计划 将由该领域的思想领袖以及早期职业研究员，三个主题演讲的讲座进行讲座 演讲，两个由专家小组主持的互动案例讨论以及包括 演示文稿和两个海报会议。我们2019年研讨会计划中介绍的新主题将包括： 艰难梭菌，会影响免疫功能低下的患者和抗菌病 管理。将维持我们2017年研讨会的成功元素，包括以下内容 主题：呼吸道病毒疾病，巨细胞病毒，真菌疾病，微生物组和免疫疗法。 该活动的一个独特而创新的特征是我们专注于支持受训者的出勤和参与， 特别是来自代表性不足的妇女和个人。我们的目标是通过 提供大量的受训者津贴并构建我们的计划以促进有意义的互动 在今天的领导者和将在未来几十年中为此做出贡献的后起之秀之间。我们的目标 促进有关免疫功能低下宿主中传染病的生产性讨论，推动了进度 该领域的当前问题以及促进知识的传播，以改善临床实践 在全国范围内。这次会议通过暴露早期职业学员来加强培训管道 在支持学员（包括我们的NIH支持T32培训计划中的那些）诱人的领域，以磨练 他们的技能和获得独立职业所需的知名度。