Multidisciplinary Training in Ethnic Diversity and Cancer Disparities

种族多样性和癌症差异的多学科培训

• 批准号: 9889916
• 负责人: Christopher Alan Haiman
• 金额: $ 42.6万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9889916
• 关键词: Training; cancer health disparity; ethnic diversity; multidisciplinary

At the root of health disparities is the diversity in the biological, social, cultural, behavioral, and economic characteristics of individuals and populations. The study of ethnic/racial disparities begins with an understanding of the characteristics of each group and how these characteristics affect cancer development and outcomes. This new application for a joint T32 postdoctoral training program at University of Hawaii Cancer Center (UHCC) and the University of Southern California (USC) Norris Comprehensive Cancer Center (NCCC) addresses cancer health disparities utilizing a unique resource, the Multiethnic Cohort (MEC) Study, a population-based prospective cohort study that has followed African Americans, Native Hawaiians, Japanese Americans, Latinos, and whites for the past 25 years. Linkages to cancer registries, Medicare, and other data sources provide a variety of endpoints for MEC and many other cancer disparity studies conducted at both institutions. The complementary research at UHCC and USC is supported by cutting edge cores and benefits from many years of experience. The specific aims of the proposed training program are: 1. To train postdoctoral fellows for independent careers in cancer research in diverse populations, with a specific focus on the sociocultural, nutritional, lifestyle and biological risk factors leading to cancer health disparities in a variety of ethnic/racial minorities. This program is highly unique and will leverage the long- standing (30+ years) collaboration between research programs at two NCI-designated Cancer Centers to permit a broader experience in training and tools for epidemiological research. 2. To provide extensive applied research experience in a multidisciplinary environment focusing on nutritional, molecular, genetic and translational epidemiology that builds on multiple unique racial and ethnically diverse studies of cancer. Together with strong mentorship, these studies will serve as the centerpiece for an effective transdisciplinary training, which will allow trainees to design innovative high-impact projects, and will prepare trainees for careers in cancer health disparities research. During the 5-year grant period, the training program will educate 8 postdoctoral fellows in Hawaii and 10 in Los Angeles. All trainees will be exposed to a wide range of innovative molecular and traditional cancer prevention approaches (epidemiology, biomarkers, genomics, and nutrition) to address a wide range of cancer disparity research questions across the ethnic/racial populations in Hawaii and California through the close cooperation of mentors in both locations and regular exchange visits. The dual-site training, which regular includes exchange visits, is a particular strength of the proposed training program as it will provide exposure to multi- institutional and multi-disciplinary collaborative research that builds on the expertise and long-standing collaboration between UH and USC in research, education and training.

健康差异的根源是生物学，社会，文化，行为和经济的多样性 个人和人群的特征。种族/种族差异的研究始于 了解每个组的特征以及这些特征如何影响癌症发展 和结果。这项新的申请夏威夷大学联合T32博士后培训计划 癌症中心（UHCC）和南加州大学（USC）诺里斯综合癌症中心 （NCCC）利用独特资源的多民族队列（MEC）研究解决了癌症健康差异， 遵循非洲裔美国人，夏威夷原住民，日本人的基于人群的前瞻性队列研究 在过去的25年中，美国人，拉丁裔和白人。与癌症注册机构，医疗保险和其他数据的联系 来源为MEC和许多其他癌症差异研究提供了多种终点 机构。 UHCC和USC的互补研究得到了最前沿的核心和福利的支持 来自多年的经验。拟议培训计划的具体目的是： 1。培训博士后研究员，从事不同人群中癌症研究的独立职业， 特别关注导致癌症健康的社会文化，营养，生活方式和生物危险因素 各种种族/种族少数民族的差异。该程序非常独特，将利用长期 在两个NCI指定的癌症中心的研究计划之间（30多年）的合作（30多年） 允许在流行病学研究的培训和工具方面具有更广泛的经验。 2。在跨学科环境中提供广泛的应用研究经验，以营养为重点， 分子，遗传和转化流行病学基于多种独特的种族和种族 癌症的多种研究。这些研究将作为强大的指导，将作为 有效的跨学科培训将使受训人员可以设计创新的高影响力项目， 并将为学员准备癌症健康差异研究的职业。 在5年的赠款期内，培训计划将教育8位夏威夷的博士后研究员，在Los教育10名 安吉利斯。所有学员将暴露于各种创新的分子和传统癌症预防 方法（流行病学，生物标志物，基因组学和营养）解决了广泛的癌症差异 通过密切合作 位置和定期交换访问的导师。双站点训练，常规 交换访问是拟议培训计划的特殊优势，因为它将提供多种多样 基于专业知识和长期以来的机构和多学科合作研究 UH与USC在研究，教育和培训方面的合作。