Institutional Career Development Core

机构职业发展核心

• 批准号: 9623478
• 负责人: ELLEN L BURNHAM
• 金额: $ 91.03万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9623478
• 关键词: Address; Applications Grants; Award; Biomedical Research; Businesses; Career Choice; Clinical; Clinical Investigator Award; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Colorado; Competence; Data; Development; Development Plans; Educational Curriculum; Entrepreneurship; Environment; Ethics; Faculty; Fostering; Funding; Goals; Good Clinical Practice; Grant; Health Care Research; Immersion Investigative Technique; Individual; Industry; Informatics; Institutes; Intellectual Property; Journals; Leadership; Medicine; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Modeling; Outcome; Peer Review; Phenotype; Play; Positioning Attribute; Program Development; Publications; Research; Research Methodology; Research Personnel; Research Training; Role; Science; Scientist; Secure; Training; Training Programs; Translational Research; Translations; United States National Institutes of Health; Universities; base; career; career development; community organizations; education research; ethnic diversity; experience; externship; innovation; medical schools; next generation; outreach; programs; racial diversity; response; responsible research conduct; skill acquisition; stem; success; synergism; translational scientist

PROJECT SUMMARY/ABSTRACT Recent publications emphasize a shortfall in the number of investigators and scientists entering the clinical and translational research (CTR) pipeline. In response to the crisis, NCATS KL2 career development programs play an increasingly important role in preparing the next generation of clinical-translational scientists to be capable and resilient in the face of changes in health care, research funding and academic medicine. Our overall goal is to build upon the success of our CCTSI KL2 program and to provide in the next grant cycle a comprehensive Institutional Career Development Core KL2 training program, for 5 KL2 junior investigator scholar slots for 3 years each at 75% effort, that will foster outstanding and efficient clinical-translational research education, promote clinical-translational science competence and excellence, and augment the impact of research performed by KL2 scholars. To achieve our goals, we propose 3 Specific Aims that are congruent with our conceptual model of CTR persistence developed by our CCTSI colleagues: Aim 1: Optimize the provision of individualized competency-based training in translational research methodologies, clinical trials, and data informatics, along with ethical, regulatory and Good Clinical Practice principles. Aim 2: Prepare KL2 scholars to thrive in the new collaborative research environment by fostering skill development in entrepreneurship, team- based science and mentorship. Aim 3: Assure that KL2 scholars develop and submit competitive grant applications to transition to independent investigators. These specific aims will be achieved through the use of individualized career development plans to facilitate KL2 scholar oversight and guidance by KL2 program leadership in completing milestones and goals. KL2 scholars along with their mentors, as a dyad, will complete the yearlong CO-Mentor program to solidify effective mentoring relationships. Immersion into CTR will involve meaningful CTR research experiences with the scholar's mentors to support the transition to independence. Innovative experiences, in the form of externships with community organizations and businesses/industry will be provided. Career development initiatives will be offered in team science, entrepreneurship, data informatics and translation through dissemination and implementation. All scholars will complete training in the responsible conduct of research and Good Clinical Practice. KL2 program leadership will be engaged in several activities to increase diversity including partnering with the School of Medicine's Office of Diversity and Inclusion and the University's Office of Inclusion and Outreach. All KL2 scholars will participate in the KL2 Curriculum, and many of the programs will be available to other junior faculty with NIH K or equivalent awards, enhancing CTR research training and collaboration across the CCTSI and the University. Key outcomes for the KL2 program will be the success rate of KL2 scholars in remaining in CTR positions, securing grants (transition to R and U type awards), number of peer-reviewed publications in high impact journals, development of intellectual property and racial and ethnic diversity.

项目概要/摘要 最近的出版物强调了进入临床和临床研究的研究人员和科学家数量的短缺。 转化研究（CTR）管道。为应对危机，NCATS KL2职业发展计划发挥作用 在培养下一代临床转化科学家的能力方面发挥着越来越重要的作用 面对医疗保健、研究经费和学术医学的变化，具有弹性。我们的总体目标是 以我们 CCTSI KL2 计划的成功为基础，并在下一个资助周期提供全面的 机构职业发展核心 KL2 培训计划，适用于 5 个 KL2 初级研究员学者名额，适用于 3 个 年每年投入 75% 的努力，这将促进杰出、高效的临床转化研究教育， 提高临床转化科学能力和卓越性，并扩大研究的影响 由KL2学者进行。为了实现我们的目标，我们提出了 3 个与我们的目标一致的具体目标 由我们的 CCTSI 同事开发的 CTR 持久性概念模型： 目标 1：优化提供 转化研究方法、临床试验和数据方面的个性化能力培训 信息学，以及道德、监管和良好临床实践原则。目标 2：让 KL2 学者做好准备 通过促进创业、团队技能发展，在新的合作研究环境中蓬勃发展 基于科学和指导。目标 3：确保 KL2 学者开发并提交有竞争力的资助 过渡到独立调查员的申请。这些具体目标将通过使用 个性化的职业发展计划，以促进 KL2 学者对 KL2 项目的监督和指导 领导完成里程碑和目标。 KL2 学者与他们的导师作为二人组将完成 为期一年的共同导师计划，以巩固有效的指导关系。沉浸在 CTR 中将涉及 与学者导师一起获得有意义的 CTR 研究经验，以支持向独立的过渡。 以社区组织和企业/行业实习的形式提供创新经验 假如。将在团队科学、创业、数据信息学和 通过传播和实施进行翻译。所有学者将完成负责人的培训 进行研究和良好临床实践。 KL2 项目领导层将参与多项活动 增加多样性，包括与医学院的多样性和包容性办公室以及 大学包容和外展办公室。所有 KL2 学者都将参加 KL2 课程，并且许多 的项目将提供给其他获得 NIH K 或同等奖项的初级教师，从而增强 CTR 研究 CCTSI 和大学之间的培训和合作。 KL2 计划的主要成果将是 KL2 学者保留 CTR 职位、获得资助（过渡到 R 和 U 型奖项）的成功率， 高影响力期刊中经过同行评审的出版物数量、知识产权的发展和种族问题 和种族多样性。