Institutional Career Development Core

机构职业发展核心

• 批准号: 9623478
• 负责人: ELLEN L BURNHAM
• 金额: $ 91.03万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9623478
• 关键词: Address; Applications Grants; Award; Biomedical Research; Businesses; Career Choice; Clinical; Clinical Investigator Award; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Colorado; Competence; Data; Development; Development Plans; Educational Curriculum; Entrepreneurship; Environment; Ethics; Faculty; Fostering; Funding; Goals; Good Clinical Practice; Grant; Health Care Research; Immersion Investigative Technique; Individual; Industry; Informatics; Institutes; Intellectual Property; Journals; Leadership; Medicine; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Modeling; Outcome; Peer Review; Phenotype; Play; Positioning Attribute; Program Development; Publications; Research; Research Methodology; Research Personnel; Research Training; Role; Science; Scientist; Secure; Training; Training Programs; Translational Research; Translations; United States National Institutes of Health; Universities; base; career; career development; community organizations; education research; ethnic diversity; experience; externship; innovation; medical schools; next generation; outreach; programs; racial diversity; response; responsible research conduct; skill acquisition; stem; success; synergism; translational scientist; Address; Applications Grants; Award; Biomedical Research; Businesses; Career Choice; Clinical; Clinical Investigator Award; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Colorado; Competence; Data; Development; Development Plans; Educational Curriculum; Entrepreneurship; Environment; Ethics; Faculty; Fostering; Funding; Goals; Good Clinical Practice; Grant; Health Care Research; Immersion Investigative Technique; Individual; Industry; Informatics; Institutes; Intellectual Property; Journals; Leadership; Medicine; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Modeling; Outcome; Peer Review; Phenotype; Play; Positioning Attribute; Program Development; Publications; Research; Research Methodology; Research Personnel; Research Training; Role; Science; Scientist; Secure; Training; Training Programs; Translational Research; Translations; United States National Institutes of Health; Universities; base; career; career development; community organizations; education research; ethnic diversity; experience; externship; innovation; medical schools; next generation; outreach; programs; racial diversity; response; responsible research conduct; skill acquisition; stem; success; synergism; translational scientist

PROJECT SUMMARY/ABSTRACT Recent publications emphasize a shortfall in the number of investigators and scientists entering the clinical and translational research (CTR) pipeline. In response to the crisis, NCATS KL2 career development programs play an increasingly important role in preparing the next generation of clinical-translational scientists to be capable and resilient in the face of changes in health care, research funding and academic medicine. Our overall goal is to build upon the success of our CCTSI KL2 program and to provide in the next grant cycle a comprehensive Institutional Career Development Core KL2 training program, for 5 KL2 junior investigator scholar slots for 3 years each at 75% effort, that will foster outstanding and efficient clinical-translational research education, promote clinical-translational science competence and excellence, and augment the impact of research performed by KL2 scholars. To achieve our goals, we propose 3 Specific Aims that are congruent with our conceptual model of CTR persistence developed by our CCTSI colleagues: Aim 1: Optimize the provision of individualized competency-based training in translational research methodologies, clinical trials, and data informatics, along with ethical, regulatory and Good Clinical Practice principles. Aim 2: Prepare KL2 scholars to thrive in the new collaborative research environment by fostering skill development in entrepreneurship, team- based science and mentorship. Aim 3: Assure that KL2 scholars develop and submit competitive grant applications to transition to independent investigators. These specific aims will be achieved through the use of individualized career development plans to facilitate KL2 scholar oversight and guidance by KL2 program leadership in completing milestones and goals. KL2 scholars along with their mentors, as a dyad, will complete the yearlong CO-Mentor program to solidify effective mentoring relationships. Immersion into CTR will involve meaningful CTR research experiences with the scholar's mentors to support the transition to independence. Innovative experiences, in the form of externships with community organizations and businesses/industry will be provided. Career development initiatives will be offered in team science, entrepreneurship, data informatics and translation through dissemination and implementation. All scholars will complete training in the responsible conduct of research and Good Clinical Practice. KL2 program leadership will be engaged in several activities to increase diversity including partnering with the School of Medicine's Office of Diversity and Inclusion and the University's Office of Inclusion and Outreach. All KL2 scholars will participate in the KL2 Curriculum, and many of the programs will be available to other junior faculty with NIH K or equivalent awards, enhancing CTR research training and collaboration across the CCTSI and the University. Key outcomes for the KL2 program will be the success rate of KL2 scholars in remaining in CTR positions, securing grants (transition to R and U type awards), number of peer-reviewed publications in high impact journals, development of intellectual property and racial and ethnic diversity.

项目摘要/摘要 最近的出版物强调了进入临床和科学家的数量和科学家的缺口 翻译研究（CTR）管道。为了应对危机，NCATS KL2职业发展计划播放 越来越重要的作用在准备下一代临床翻译科学家能够 面对医疗保健，研究资金和学术医学的变化，并且有韧性。我们的总体目标是 以我们CCTSI KL2计划的成功为基础，并在下一个赠款周期中提供全面 机构职业发展核心KL2培训计划，针对3个KL2初级研究者学者老虎机3 每年以75％的努力，这将促进出色，有效的临床翻译研究教育， 促进临床翻译科学能力和卓越，并增强研究的影响 由KL2学者表演。为了实现我们的目标，我们提出了与我们的3个特定目标 CCTSI同事开发的CTR持久性的概念模型：目标1：优化提供 转化研究方法，临床试验和数据的个性化培训 信息学，以及道德，法规和良好的临床实践原则。目标2：准备KL2学者 通过促进企业家精神的技能发展，团队 - 基于科学和指导。目标3：确保KL2学者发展和提交竞争性赠款 向独立调查员过渡的申请。这些具体目标将通过使用 个性化的职业发展计划，以促进KL2学者的监督和KL2计划指导 完成里程碑和目标的领导能力。 KL2学者及其导师作为二元组将完成 巩固有效指导关系的为期一年的副委员会计划。浸入CTR将涉及 有意义的CTR研究经历了学者的导师，以支持向独立的过渡。 创新的经验，以社区组织和企业/行业的实质形式 假如。职业发展计划将在团队科学，企业家精神，数据信息学和 通过传播和实施翻译。所有学者将完成负责任的培训 进行研究和良好的临床实践。 KL2计划领导将从事几项活动 增加多样性，包括与医学院多样性与包容办公室合作 大学包容与外展办公室。所有KL2学者将参加KL2课程，许多学者 该计划将提供给其他NIH K或同等奖项的初级教师，从而增强CTR研究 跨CCTSI和大学的培训与协作。 KL2程序的关键结果将是 KL2学者在CTR职位中保留的成功率，获得赠款（过渡到R和U类型奖）， 高影响期刊中的同行评审出版物数量，知识产权的发展和种族 和种族多样性。