Western North Carolina StrokeNet

北卡罗来纳州西部中风网

• 批准号: 9753382
• 负责人: CHERYL D BUSHNELL
• 金额: $ 30.29万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9753382
• 关键词: Acute; Adult; Advocacy; Advocate; Baptist Church; Blood Vessels; Caring; Catchment Area; Childhood; Clinical; Clinical Research; Clinical Trials; Cognitive; Collaborations; Communities; Community Developments; Community Health; Community Networks; Community Outreach; Conduct Clinical Trials; Dedications; Effectiveness; Emergency Medicine; Enrollment; Evaluation; Funding; Goals; Health; Heart; Hospitals; Individual; Industry; Information Dissemination; Intervention; Intervention Trial; Interventional radiology; Lead; Leadership; Medical center; Methodology; Mission; Modeling; National Institute of Neurological Disorders and Stroke; Neurology; North Carolina; Outcome; Patient-Focused Outcomes; Patients; Phase; Population; Presbyterian Church; Prevention; Protocols documentation; Provider; Recovery; Rehabilitation therapy; Research; Research Personnel; Rural; Seasons; Secondary Prevention; Services; Site; Stroke; Stroke Belt; Stroke prevention; StrokeNet clinical trials; StrokeNet trials; Technology; Telemedicine; Testing; Time; Triad Acrylic Resin; Underrepresented Minority; United States National Institutes of Health; Virginia; acute stroke; care outcomes; clinical practice; design; experience; forest; improved; improved outcome; neurosurgery; novel; novel strategies; novel therapeutics; operation; outreach; outreach program; pilot trial; post stroke; pragmatic trial; programs; recruit; rural area; rural patients; socioeconomics; stroke clinical trials; stroke education; stroke outcome; stroke patient; stroke recovery; stroke rehabilitation; stroke therapy; stroke trials; success; treatment as usual; treatment trial; urban area

Summary Improving the outcomes of patients with stroke requires evaluation of new therapeutics, technology, or care models through clinical trials. A network of dedicated sites, such as StrokeNet, enables enrollment of large numbers of patients quickly and efficiently, testing effectiveness of these new treatment options faster. Wake Forest Baptist Health (WFBH) has partnered with 3 sites to develop the Western North Carolina (NC) StrokeNet. Our network includes 4 of the 6 comprehensive stroke centers in NC, the heart of the Stroke Belt: Wake Forest Baptist Health (RCC), Novant Forsyth Medical Center, Novant Presbyterian, and Mission Health. The referral and telestroke outreach of our network includes the Piedmont region and nearly all of NC west of the Piedmont, and part of southern Virginia--over 4 million individuals,16,800 square miles, and over 4,000 stroke patients admitted to these hospitals per year. We serve a diverse socioeconomic and rural catchment area, a population typically under-represented in clinical trials. WFBH has been highly successful with the design and conduct of clinical trials, including phase II, III, and pragmatic trials. WFBH's enrollment in all trials, and the combination of WFBH and Novant enrollment in NINDS sponsored trials has been outstanding. Mission and Novant Presbyterian have each participated in our pragmatic trial of post-acute services (COMPASS), each enrolling over 300 patients, and have success with enrolling in NIH and industry sponsored studies. We have experienced stroke leadership at the RCC, with Dr. Bushnell (neurology) as PI, Dr. Wolfe (vascular neurosurgery), co-PI, and Dr. Duncan (neurology), co-I, as well as a seasoned StrokeNet program manager, Ms. Sylvia Coleman, who will assist the partnering sites with trial selection, startup, and operations to meet the goals of efficiency and enrollment with StrokeNet clinical trials. The RCC team has experience in design and implementation of rehab/recovery and pragmatic trials, and development of community networks that will be beneficial to recruitment, retention, and dissemination of results—an asset to the overall StrokeNet. Our aims are: AIM 1: Successfully implement StrokeNet trials in the Piedmont Triad and Western NC and design new stroke treatment trials. AIM 2: Implement a novel approach for recruitment, retention, and ascertainment of outcomes through 2a) existing telemedicine networks for recruitment and ascertainment of outcomes; and 2b) Creating the Western NC Advocacy Committee that will include patient advocates, patients, EMS providers, and clinicians to establish best strategies for community engagement; AIM 3: Develop community outreach programs to engage rural and urban communities in our referral region in StrokeNet trials.

概括 改善中风患者的结果需要评估新的疗法，技术或护理 通过临床试验模型。诸如Strotenet之类的专用网站网络，可以招收大型网站 快速有效的患者数量，测试这些新治疗方案的有效性更快。唤醒 Forest Baptist Health（WFBH）已与3个地点合作开发北卡罗来纳州西部（NC） Strokenet。我们的网络包括北卡罗来纳州的6个综合中风中心中的4个，这是中风的核心 皮带：Wake Forest Baptist Health（RCC），Novant Forsyth医疗中心，Novant Presbyterian和Mission 健康。我们网络的推荐和端罗克宣传包括皮埃蒙特地区和几乎所有的NC 皮埃蒙特（Piedmont）以及南弗吉尼亚州的一部分 - 超过400万个人，16,800平方英里及以上 每年有4,000名中风患者进入这些医院。我们为潜水员的社会经济和农村服务 集水区，通常在临床试验中代表性不足的人群。 WFBH非常成功 随着临床试验的设计和行为，包括II期，III和务实试验。 WFBH的入学人数 所有试验以及Ninds赞助试验中的WFBH和Novant入学率的结合已是 杰出的。任务和诺维特长老会都参加了我们急性后的务实审判 服务（指南针），每个人都有300多名患者，并在入学NIH和行业方面取得了成功 赞助研究。我们在RCC上经历了中风领导，Bushnell博士（神经病学）为PI， Wolfe博士（血管神经外科），Co-Pi和Duncan博士（神经病学），Co-I以及经验丰富的strokenet 计划经理Sylvia Coleman女士，他将协助合作网站进行试用，初创公司和 通过Strokenet临床试验实现效率和入学目标的操作。 RCC团队有 在康复/恢复和务实试验的设计和实施方面的经验以及开发 社区网络将有利于招聘，保留和传播结果的社区网络，这是一种资产 整体拼写物。我们的目标是： AIM 1：在皮埃蒙特三合会和西部北卡罗来纳州成功实施Strosenet试验并设计新中风 治疗试验。 目标2：实施一种新颖的方法，以通过2A招募，保留和确定结果） 现有的远程医疗网络，用于招募和确定结果；和2b）创建西方 NC倡导委员会将包括患者倡导者，患者，EMS提供者和临床医生 建立社区参与的最佳策略； 目标3：制定社区外展计划，以吸引我们在我们推荐地区的农村和城市社区 Strokenet试验。