iTAKL: Imaging Telemetry And Kinematic modeLing in youth football

iTAKL：青少年足球中的成像遥测和运动学建模

基本信息

批准号：
9306963
负责人：
GERARD A. GIOIA
金额：
$ 64.45万
依托单位：
WAKE FOREST UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-01 至 2019-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9306963
关键词：
12 year old Adverse effects Age Anisotropy Area Athletic Attention Behavior assessment Biomechanics Biometry Brain Brain Concussion Brain Injuries Child Childhood Cognitive Collaborations Collection Computer Simulation Control Groups Craniocerebral Trauma Data Development Diffuse Diffusion Magnetic Resonance Imaging Elements Equipment Functional Magnetic Resonance Imaging Funding Head Health Sciences Image Incidence Injury Investments Linear Regressions Magnetic Resonance Imaging Magnetoencephalography Manufactured football Measures Methods Modeling Monitor Motion Neurocognitive Neuropsychology Participant Perfusion Predisposition Recording of previous events Recruitment Activity Regression Analysis Research Research Personnel Rest Rotation Scanning Seasons Slow-Wave Sleep Spin Labels Sports System Target Populations Techniques Telemetry Time Translating Traumatic Brain Injury United States National Institutes of Health Universities Work Youth base clinical epidemiology cognitive change cognitive testing college data acquisition data modeling design executive function experience forest gray matter head impact high school instrument kinematics mild traumatic brain injury multimodality neuroimaging neuroinformatics pediatric traumatic brain injury prevent prospective public health relevance research clinical testing

项目摘要

DESCRIPTION (provided by applicant). Football head injuries involve significant forces and can result in mild to severe traumatic brain injuries. While this has received increasing attention at the professional, collegiate, and high school levels, there is scarce if any data available for participants in the youth leagues (8-12 years old). This study will relate information about head motion during a hit in youth football to neurocognitive and imaging data to determine the effects of subconcussive impacts, and the true incidence of cognitive and objective imaging changes. All elements of this study focus on the objective to increase understanding of pediatric mild Traumatic Brain Injury (mTBI) and prospectively collect biomechanical, imaging, functional, and computational modeling data on a scale never before attempted. This project integrates neuroinformatics work and the computational modeling techniques developed by Drs. Maldjian and Stitzel at Wake Forest University Health Sciences (WFUHS). It leverages the investments by WFUHS which has identified, instrumented, and begun recruiting the target population and funding the initial year as part of our ongoing work in this area of critical public importance. Th long term benefit of the research will be to allow equipment designers, researchers, and clinicians to better prevent, mitigate, identify and treat injuries to help make youth league football a safer activity for millions of children.

描述（由申请人提供）。足球头部受伤涉及重大力量，可能导致轻度至重度创伤性脑损伤。虽然这受到了越来越多的关注在专业，大学和高中级别上，如果有任何数据可供青年联赛（8-12岁）的参与者提供数据。这项研究将将有关青年足球击中期间头部运动的信息与神经认知和成像数据联系起来，以确定亚语影响的影响以及认知和客观成像变化的真正发生率。这项研究的所有元素都集中在目标上，以增加对小儿轻度创伤性脑损伤（MTBI）的了解，并前瞻性地收集生物力学，成像，功能和计算模型，以前从未尝试过的规模。该项目集成了DRS开发的神经信息学和计算建模技术。 Wake Forest University Health Sciences（WFUHS）的Maldjian和Stitzel。它利用了WFUHS的投资，该投资已确定，仪器并开始招募目标人群并为第一年提供资金，这是我们在这一至关重要的公众重要性领域正在进行的工作的一部分。研究的长期利益将是允许设备设计师，研究人员和临床医生更好地预防，减轻，识别和治疗伤害，以帮助使青年联盟足球成为数百万儿童的更安全活动。