Protein Production Group

蛋白质生产组

• 批准号: 9315166
• 负责人: Fei Philip Gao
• 金额: $ 6.2万
• 依托单位: UNIVERSITY OF KANSAS LAWRENCE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9315166
• 关键词: ART protein; Area; Centers of Research Excellence; Client; Cloning; Ensure; Faculty; Fee-for-Service Plans; Fees; Laboratories; Methods; Mutagenesis; Pattern; Phase; Production; Proteins; Research Personnel; Role; Scientist; Services; Techniques; Time; Training; Universities; experience; member; protein expression; protein function; protein purification; protein structure; protein structure function

A COBRE Center dedicated to studying protein structure/function must have a means for producing a wide variety of proteins. The COBRE-PSF Protein Production Group (Core B) fulfills this role by serving the following functions. 1) It maintains a state-of-the-art facility for cloning, mutagenesis and protein production that is accessible to COBRE investigators, other Core Lab users, and PPG staff members. 2) It produces and delivers high quality proteins in a reliable and efficient manner on a fee-for-service basis. 3) It provides clients with expert advice and hands-on training in any or all of the strategies and techniques used the PPG Core Lab. The PPG staff consists of a Director, Dr. Philip Gao, and two experineced full time staff scientists. It is guided by a Steering committee comprised of three faculty researchers experienced in the art of protein production and characterization. During Phase III the PPG Core will transition from a pattern of support by COBRE plus user fees to one of basal support by the University plus user fees; this will ensure its long-term sustainability.

致力于研究蛋白质结构/功能的鞋底中心必须具有产生宽阔的手段 各种蛋白质。 COBRE-PSF蛋白质生产组（核心B）通过服务来履行这一角色 以下功能。 1）它维护了克隆，诱变和蛋白质生产的最新设施 毛绒调查人员，其他核心实验室用户和PPG工作人员可以访问这一点。 2）它产生 并以可靠和高效的方式提供高质量的蛋白质。 3）它提供了 在使用PPG的任何或所有策略和技术中，都有专家建议和动手培训的客户 核心实验室。 PPG的工作人员由一名董事Philip Gao博士和两名实验的全职员工科学家组成。 它由指导委员会指导，该委员会由三名蛋白质艺术经验丰富 生产和表征。在第三阶段期间，PPG核心将从支撑模式过渡 Cobre Plus用户费用为大学的基础支持之一以及用户费用；这将确保其长期 可持续性。