The Clinical Research/Reproductive Scientist Training Program (CREST)

临床研究/生殖科学家培训计划 (CREST)

• 批准号: 9250796
• 负责人: Nanette F. Santoro
• 金额: $ 16.38万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-04-15 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9250796
• 关键词: 4-ethoxymethylene-2-phenyl-2-oxazoline-5-one; Address; Adult; American; Andrology; Area; Career Choice; Certification; Clinical Research; Clinical Trials Database; Data Analyses; Data Set; Data Sources; Databases; Discipline of obstetrics; Disease; Endocrinology; Fertility; Future; Goals; Gynecology; Health; Infertility; Life; Menopause; Methods; Multi-Institutional Clinical Trial; NCI Scholars Program; NIH Program Announcements; National Institute of Child Health and Human Development; Outcome; Ovulation Induction; Oxygen; Perception; Persons; Phase; Physicians; Physiological; Polycystic Ovary Syndrome; Population; Population Sciences; Pregnancy; Pregnancy Outcome; Process; Registries; Reproduction; Reproductive Endocrinology; Reproductive Medicine; Research; Research Personnel; Research Project Grants; Resources; Sampling; Schedule; Science; Scientist; Series; Societies; Testing; Training; Training Activity; Training Programs; United States National Institutes of Health; Universities; Vision; Woman; biobank; certificate program; clinical application; contraceptive practice; design; epidemiology study; innovation; meetings; novel; physiologic stressor; programs; public health relevance; reproductive; reproductive epidemiology; response; skill acquisition; skills; undergraduate student

DESCRIPTION (provided by applicant): In response to concerns about the decline in physician scientists, the relative lack of well- designed and well-executed clinical and epidemiological research in reproductive medicine, and a perception that current trainees in the Reproductive Endocrinology and Infertility subspecialty of Obstetrics and Gynecology were opting out of research career paths, the Clinical Research/Reproductive Scientist Training Program (CREST) Program was established as a partnership among key components that comprised and facilitated the training program: the Deputy Director of the National Institute for Child Health and Human Development, the Program in Reproductive and Adult Endocrinology, the American Society for Reproductive Medicine, and the Clinical Research Training Program at Duke University. Didactic training modules are designed to be online to accommodate clinicians. Weekend seminars are scheduled in conjunction with the annual American Society for Reproductive Medicine meeting (once a year) and on the NIH campus (6 months apart from the ASRM meeting). Graduates receive a certificate in Clinical Research. A group thesis project involving analysis of a large data set and a testing of skill acquisition became an optional, informal activity in the second year of CREST, undertaken after completion of the online certificate program. The CREST Program's impact and outcomes are promising and indicate that it is achieving its goal. The present proposal seeks to formalize the second year of the program to specifically incorporate a team science thesis project and promote the application of CREST Scholars' newly acquired skills to query existing population and clinical trial databases and perform secondary data analyses (Specific Aim 1) and to expand the available data sets for the second year of CREST training to include multiple data sources in Reproductive Endocrinology and Infertility, and Andrology (Specific Aim #2). These resources will provide a descriptive dataset for outcomes analysis in fertility and contraceptive practice, and generate new hypotheses for future research. The goals of the current proposal are particularly relevant to the NIH visioning process for reproduction and pregnancy research, which has both recognized the importance of viewing pregnancy as a physiologic stressor, and examining the preconceptual phase of life as a predictor of pregnancy health and disease.

描述（由申请人提供）：回应对医师科学家的减少的关注，相对缺乏生殖医学中的临床和流行病学研究的相对缺乏，以及人们认为，当前学员在生殖内分泌学上的受训者和临床研究培训计划（临床研究）的研究（作为培训计划的主要组成部分的合作伙伴关系：美国国家儿童健康与人类发展研究所副主任，生殖和成人内分泌学计划，美国生殖医学学会和杜克大学的临床研究培训计划。教学培训模块旨在在线容纳临床医生。周末研讨会安排与年度美国生殖医学会议（每年一次）和NIH校园（与ASRM会议相距6个月）结合。毕业生获得临床研究证书。小组论文项目涉及大型数据集的分析和对技能获取的测试，在完成在线证书计划后进行的第二年，在CREST的第二年中成为一项可选的非正式活动。 CREST计划的影响和成果是有希望的，并表明它正在实现其目标。 The present proposal seeks to formalize the second year of the program to specifically incorporate a team science thesis project and promote the application of CREST Scholars' newly acquired skills to query existing population and clinical trial databases and perform secondary data analyses (Specific Aim 1) and to expand the available data sets for the second year of CREST training to include multiple data sources in Reproductive Endocrinology and Infertility, and Andrology (Specific Aim #2).这些资源将为生育和避孕实践中的结果分析提供描述性数据集，并为未来的研究产生新的假设。当前提案的目标与NIH远景和妊娠研究的远见过程特别相关，该过程既认识到将怀孕视为生理压力源的重要性，又认识到生命的概念概念阶段，以预测妊娠健康和疾病的预测指标。