Vermont Center on Behavior and Health

佛蒙特州行为与健康中心

基本信息

批准号：
9324315
负责人：
Stephen T Higgins
金额：
$ 185.29万
依托单位：
UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-09-15 至 2018-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9324315
关键词：
Achievement Adult Area Behavior Behavior Therapy Behavioral Biological Body Weight decreased Breast Cancer survivor Cardiac rehabilitation Cell Nucleus Centers of Research Excellence Cessation of life Child Chronic Disease Clinical Research Collaborations Community Healthcare Cost Effectiveness Analysis Decision Making Development Doctor of Philosophy Econometric Models Economic Models Education Emerging Technologies Evaluation Faculty Food Functional Magnetic Resonance Imaging Funding Goals Health Health Care Costs Health Policy Incentives Individual Individual Differences Interdisciplinary Study International Intervention Intervention Studies Kentucky Knowledge Lead Leadership Low income Medical Mentors Metabolic Diseases Mission Neurobiology Noninfiltrating Intraductal Carcinoma Obesity Outcome Overweight Paper Patients Pattern Personal Behavior Psychopathology Public Health Quality of life Recruitment Activity Regimen Research Research Infrastructure Research Personnel Risk Risk Behaviors Risk Factors Science Scientific Advances and Accomplishments Scientist Senior Scientist Socioeconomic Status Strategic Planning Substance abuse problem United States National Institutes of Health Universities Vermont Woman Work behavior change behavioral economics behavioral study career development clinical care college cost effectiveness design disadvantaged population discount discounting disparity reduction effective intervention executive function financial incentive gestational weight gain health disparity health organization improved instrument interdisciplinary collaboration interest laptop next generation organizational structure physical inactivity population health premature programs public health relevance success symposium therapy development

项目摘要

DESCRIPTION (provided by applicant): This is a revised application for support to establish a Center for Biomedical Research Excellence (COBRE) in Behavior and Health at the University of Vermont (UVM). The proposed center will investigate relationships between personal behaviors and risk for chronic disease and premature death. Unhealthy personal behaviors (e.g., substance abuse, physical inactivity) account for 40% of premature deaths in the U.S. annually and substantially increase healthcare costs and health disparities. There is a tremendous need for (a) greater scientific understanding of the mechanisms underpinning vulnerability to these risk behaviors and (b) more effective interventions to promote behavior change. We will approach these challenges from a behavioral economics conceptual framework. This effort will involve key interdisciplinary collaborations (a) across multiple departments and colleges within UVM, (b) with key Vermont community healthcare leaders, and (c) with other universities, including two from IDeA states (Brown University and University of Kentucky). Specific Aims of this proposal are: Aim 1: Establish the cores necessary to develop and sustain a vibrant interdisciplinary center of research excellence. Goals of this aim include developing (a) an Administrative Core that provides leadership, organizational structure, intellectual infrastructure, a mentoring plan, fiscal management, and strategic planning for fiscal support beyond COBRE funding; (b) a Behavioral Economics and Intervention Sciences Core that supports intervention development and evaluation, econometric modeling of cost effectiveness, and the study of health-related decision making and its neurobiological underpinnings, and (c) a Collaboration, Dissemination, and Education Core to facilitate those key missions. Aim 2: Support the selection and career development of excellent junior\faculty Project Directors (PDs) who will become the nucleus of the center. The PDs and their research topics are: (1) Robert Althoff, MD, PhD, Shared Mechanisms in Child Dysregulation, Adult Psychopathology, and Metabolic Disorders; (2) Diann Gaalema, PhD, Incentives to Improve Cardiac Rehabilitation Participation in Low-income Patients; (3) Julie Phillips, MD, Incentives Targeting Gestational Weight Gain in Overweight/Obese Low-income Women; (4) Kim Dittus, MD, PhD, Predictors of Weight Loss Success in Overweight Breast Cancer Survivors; (5) Brian Sprague, PhD, Behaviors, Chronic Disease, and Quality of Life After Ductal Carcinoma In Situ. The proposed center will bring together an interdisciplinary group of accomplished senior scientists, promising junior investigators, and distinguished advisors and collaborators to work closely together to establish a center of excellence in an area of clinical research that is vitall important to the U.S. public health.

描述（由申请人提供）：这是一份修订后的申请，旨在支持在佛蒙特大学 (UVM) 建立行为与健康领域的生物医学卓越研究中心 (COBRE)。拟议的中心将调查个人行为与慢性病和过早死亡风险之间的关系。在美国，每年 40% 的过早死亡是由不健康的个人行为（例如药物滥用、缺乏身体活动）造成的，并大幅增加了医疗费用和健康差距。迫切需要（a）对这些风险行为脆弱性的机制有更科学的了解，以及（b）采取更有效的干预措施来促进行为改变。我们将从行为经济学概念框架来应对这些挑战。这项工作将涉及 (a) UVM 内多个院系和学院之间的关键跨学科合作，(b) 与佛蒙特州主要社区医疗保健领导者的合作，以及 (c) 与其他大学的合作，其中包括来自 IDeA 州的两所大学（布朗大学和肯塔基大学）。该提案的具体目标是：目标 1：建立发展和维持充满活力的跨学科卓越研究中心所需的核心。这一目标包括制定 (a) 一个行政核心，提供领导力、组织结构、知识基础设施、指导计划、财政管理和 COBRE 资金之外的财政支持战略规划； (b) 行为经济学和干预科学核心，支持干预措施的开发和评估、成本效益的计量经济学建模以及健康相关决策及其神经生物学基础的研究，以及 (c) 协作、传播和教育核心促进这些关键任务。目标2：支持优秀初级\教师项目总监（PD）的选拔和职业发展，他们将成为中心的核心。博士生及其研究主题是：(1) Robert Althoff，医学博士、哲学博士，儿童失调、成人精神病理学和代谢紊乱的共享机制； (2) Dinn Gaalema 博士，提高低收入患者心脏康复参与度的激励措施； (3) Julie Phillips，医学博士，针对超重/肥胖低收入妇女妊娠期体重增加的激励措施； (4) Kim Dittus，医学博士、博士，超重乳腺癌幸存者减肥成功的预测因素； (5) Brian Sprague 博士，行为、慢性疾病和导管原位癌后的生活质量。拟议的中心将汇集一个由有成就的资深科学家、有前途的初级研究人员以及杰出的顾问和合作者组成的跨学科小组，紧密合作，在对美国公共卫生至关重要的临床研究领域建立一个卓越中心。