Vermont Center on Behavior and Health

佛蒙特州行为与健康中心

基本信息

批准号：
8432171
负责人：
Stephen T Higgins
金额：
$ 233.85万
依托单位：
UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-09-15 至 2018-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8432171
关键词：
Accounting Achievement Adult Area Behavior Behavior Therapy Behavioral Biological Body Weight decreased Cancer Survivor Cardiac Cell Nucleus Centers of Research Excellence Cessation of life Child Chronic Disease Clinical Research Collaborations Commit Community Healthcare Decision Making Development Disadvantaged Doctor of Philosophy Econometric Models Economic Models Economics Education Emerging Technologies Evaluation Faculty Food Functional Magnetic Resonance Imaging Funding Goals Health Health Care Costs Health Policy Health behavior Incentives Individual Individual Differences Interdisciplinary Study International Intervention Intervention Studies Kentucky Knowledge Lead Leadership Low income Medical Mentors Metabolic Diseases Mission Neurobiology Noninfiltrating Intraductal Carcinoma Obesity Outcome Overweight Paper Patients Pattern Personal Behavior Population Psychopathology Public Health Qualifying Quality of life Recruitment Activity Regimen Rehabilitation therapy Research Research Infrastructure Research Personnel Risk Risk Behaviors Risk Factors Science Scientific Advances and Accomplishments Scientist Senior Scientist Socioeconomic Status Strategic Planning Substance abuse problem United States National Institutes of Health Universities Vermont Weight Gain Woman Work behavior change career development clinical care college cost effectiveness design discounting effective intervention executive function financial incentive health disparity health organization improved instrument interdisciplinary collaboration interest laptop malignant breast neoplasm next generation organizational structure population health premature programs success symposium therapy development

Accounting Achievement Adult Area Behavior Behavior Therapy Behavioral Biological Body Weight decreased Cancer Survivor Cardiac Cell Nucleus Centers of Research Excellence Cessation of life Child Chronic Disease Clinical Research Collaborations Commit Community Healthcare Decision Making Development Disadvantaged Doctor of Philosophy Econometric Models Economic Models Economics Education Emerging Technologies Evaluation Faculty Food Functional Magnetic Resonance Imaging Funding Goals Health Health Care Costs Health Policy Health behavior Incentives Individual Individual Differences Interdisciplinary Study International Intervention Intervention Studies Kentucky Knowledge Lead Leadership Low income Medical Mentors Metabolic Diseases Mission Neurobiology Noninfiltrating Intraductal Carcinoma Obesity Outcome Overweight Paper Patients Pattern Personal Behavior Population Psychopathology Public Health Qualifying Quality of life Recruitment Activity Regimen Rehabilitation therapy Research Research Infrastructure Research Personnel Risk Risk Behaviors Risk Factors Science Scientific Advances and Accomplishments Scientist Senior Scientist Socioeconomic Status Strategic Planning Substance abuse problem United States National Institutes of Health Universities Vermont Weight Gain Woman Work behavior change career development clinical care college cost effectiveness design discounting effective intervention executive function financial incentive health disparity health organization improved instrument interdisciplinary collaboration interest laptop malignant breast neoplasm next generation organizational structure population health premature programs success symposium therapy development

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项目摘要

DESCRIPTION (provided by applicant): This is a revised application for support to establish a Center for Biomedical Research Excellence (COBRE) in Behavior and Health at the University of Vermont (UVM). The proposed center will investigate relationships between personal behaviors and risk for chronic disease and premature death. Unhealthy personal behaviors (e.g., substance abuse, physical inactivity) account for 40% of premature deaths in the U.S. annually and substantially increase healthcare costs and health disparities. There is a tremendous need for (a) greater scientific understanding of the mechanisms underpinning vulnerability to these risk behaviors and (b) more effective interventions to promote behavior change. We will approach these challenges from a behavioral economics conceptual framework. This effort will involve key interdisciplinary collaborations (a) across multiple departments and colleges within UVM, (b) with key Vermont community healthcare leaders, and (c) with other universities, including two from IDeA states (Brown University and University of Kentucky). Specific Aims of this proposal are: Aim 1: Establish the cores necessary to develop and sustain a vibrant interdisciplinary center of research excellence. Goals of this aim include developing (a) an Administrative Core that provides leadership, organizational structure, intellectual infrastructure, a mentoring plan, fiscal management, and strategic planning for fiscal support beyond COBRE funding; (b) a Behavioral Economics and Intervention Sciences Core that supports intervention development and evaluation, econometric modeling of cost effectiveness, and the study of health-related decision making and its neurobiological underpinnings, and (c) a Collaboration, Dissemination, and Education Core to facilitate those key missions. Aim 2: Support the selection and career development of excellent junior\faculty Project Directors (PDs) who will become the nucleus of the center. The PDs and their research topics are: (1) Robert Althoff, MD, PhD, Shared Mechanisms in Child Dysregulation, Adult Psychopathology, and Metabolic Disorders; (2) Diann Gaalema, PhD, Incentives to Improve Cardiac Rehabilitation Participation in Low-income Patients; (3) Julie Phillips, MD, Incentives Targeting Gestational Weight Gain in Overweight/Obese Low-income Women; (4) Kim Dittus, MD, PhD, Predictors of Weight Loss Success in Overweight Breast Cancer Survivors; (5) Brian Sprague, PhD, Behaviors, Chronic Disease, and Quality of Life After Ductal Carcinoma In Situ. The proposed center will bring together an interdisciplinary group of accomplished senior scientists, promising junior investigators, and distinguished advisors and collaborators to work closely together to establish a center of excellence in an area of clinical research that is vitall important to the U.S. public health.

描述（由申请人提供）：这是一个修订的支持申请，以建立佛蒙特大学（UVM）行为和健康的生物医学研究中心（Cobre）。拟议的中心将研究个人行为与慢性病和过早死亡的风险之间的关系。不健康的个人行为（例如，滥用药物，身体不活动）占美国早期死亡的40％，并大大增加医疗保健成本和健康差异。非常需要（a）对这些风险行为脆弱性的机制的更高科学理解，以及（b）更有效的干预措施以促进行为改变。我们将从行为经济学概念框架中应对这些挑战。这项工作将涉及UVM内多个部门和大学的主要跨学科合作（a）与佛蒙特州社区关键社区医疗保健领导者（b）以及（c）与其他大学（包括Idea State的两家）（布朗大学和肯塔基大学）。该提案的具体目的是：目标1：建立开发和维持卓越研究的跨学科中心所必需的核心。此目标的目标包括开发（a）提供领导力，组织结构，智力基础设施，指导计划，财政管理和战略计划的行政核心，以超越柯布尔资金的财政支持；（b）一种行为经济学和干预科学核心，该核心支持干预开发和评估，计量经济学建模以及与健康相关的决策及其神经生物学基础的研究，以及（c）协作，传播和教育核心，以促进这些关键任务。目标2：支持将成为该中心核心的优秀初级\教师项目主管（PDS）的选择和职业发展。 PDS及其研究主题是：（1）Robert Althoff，MD，PhD，儿童失调，成人心理病理学和代谢障碍中的共享机制；（2）Diann Gaalema博士，激励措施改善低收入患者的心脏康复参与；（3）医学博士朱莉·菲利普斯（Julie Phillips），针对超重/肥胖的低收入妇女妊娠体重增加的激励措施；（4）MD，PhD的Kim Dittus，超重乳腺癌幸存者体重减轻成功的预测指标；（5）Brian Sprague，博士，行为，慢性疾病和现场导管癌后的生活质量。拟议的中心将汇集一个跨学科的高级科学家，有前途的初级调查人员，杰出的顾问和合作者紧密合作，在临床研究领域建立卓越中心，这对美国公共卫生很重要。