Creating an open source operant and feeding aparatus

创建开源操作和喂养设备

• 批准号: 9549965
• 负责人: Alexxai V Kravitz
• 金额: $ 22万
• 依托单位: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9549965
• 关键词: Anxiety; Behavior; Behavioral; Biological Assay; Computer software; Devices; Food; Goals; Impulsivity; Laboratory mice; Manuscripts; Measures; Mental Depression; Motivation; Mus; Paper; Process; Publishing; Research Personnel; Sucrose; System; Testing; Touch sensation; Training; Work; addiction; base; behavior test; cost; design; feeding; interest; open source; programs; sensor; tool

We have created a low cost (<$150) operant training box, using open source tools and software. Operant training is a highly valuable form of behavioral testing that can assay motivation, impulsiveness, anxiety, depression, addiction, and many other behavioral processes. Unfortunately, most commerical suppliers provide chambers that cost on the order of $5-10K per chamber, once all software and hardware is accounted for. This is prohibitively expensive for many researchers, so we would like to develop a low cost solution that will allow our selves, our collaborators, and any other interested researchers access to this form of behavioral testing. In the past year, we have finalized design of our operant chamber, begun testing it for training mice on operant responding for food, and published a first paper outlining how to build this device. In the current year, we are preparing a new version of the device that is based around a pellet dispenser, and can be used to regulate feeding in laboratory mice, as well as investigate operant behavior. We are currently preparing a manuscript on the new version as well.

我们使用开源工具和软件创建了一个低成本（<$ 150）的操作培训框。操作训练是一种高度有价值的行为测试形式，可以测定动机，冲动，焦虑，抑郁，成瘾和许多其他行为过程。不幸的是，大多数商业供应商都提供每个会议厅$ 5-10k的订单，一旦所有软件和硬件都计算出来。对于许多研究人员来说，这非常昂贵，因此我们想开发一种低成本解决方案，该解决方案将使我们的自我，我们的合作者以及任何其他感兴趣的研究人员访问这种行为测试。 在过去的一年中，我们已经完成了操作室的设计，开始对其进行测试，以培训小鼠对食物的反应，并发表了第一篇论文，概述了如何构建该设备。 在当年，我们正在准备基于颗粒分配器的新版本的设备，可用于调节实验室小鼠的喂养，并研究操作行为。 我们目前还在新版本上准备手稿。