Overall Center Research Strategy

总体中心研究策略

• 批准号: 9333245
• 负责人: Peter G. Shields
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9333245
• 关键词: Address; Adolescent; Adult; Advertising; Affective; Area; Awareness; Biometry; Cognitive; Cohort Studies; Complement; Data; Decision Making; Development; Environment; Faculty; Fostering; Funding; Individual; Investigation; Marketing; Methodology; Modeling; Ohio; Persons; Pilot Projects; Population; Recruitment Activity; Regulation; Research; Research Personnel; Research Priority; Research Training; Resource Sharing; Rural; Rural Population; Science; Series; Smokeless Tobacco; Students; Surveys; Tobacco; Training and Education; Universities; Urban Population; Vision; Youth; data resource; design; disorder risk; experimental study; multidisciplinary; post-doctoral training; preference; tobacco regulatory science

The overall vision of The Ohio State University Center of Excellence in Regulatory Tobacco Science (OSU-CERTS) is to serve as a national leader in providing relevant scientific data to support FDA regulatory decision making in the Center for Tobacco Products. The overall theme of OSU-CERTS is to understand the reasons for underiying tobacco-product preferences, especially dual and poly-use, and how these reasons influence use in an environment of ever-changing diverse types of tobacco products. The Center will integrate this theme in a series of adolescent and adult cohort studies conducted in natural settings, complemented by well-controlled experimental studies that allow for causal inference. To accomplish the above, we will utilize a population harm model (Figure 1), where harm to the population is the result of individual disease risk and the number of persons who are exposed. The major research areas of the OSUCERTs that will assist the FDA include the impact of advertising and marketing; cognitive and affective influences in decision making; a focus on smokeless tobacco (ST) and dual use; use of both urban and rural populations to enhance generalizability; and synergistic studies that cover the range of tobacco users from adolescents to adults. Our Center will address 11 of 56 research priorities set forth by the FDA in January, 2012.

俄亥俄州立大学监管卓越中心的总体愿景 烟草科学 (OSU-CERTS) 将成为提供相关科学数据以支持烟草科学的国家领导者 FDA 烟草产品中心的监管决策。 OSU-CERTS 的总体主题是 了解烟草产品偏好的原因，特别是双重和多用途，以及如何 这些原因影响着不同类型烟草产品不断变化的环境中的使用。这 中心将把这一主题纳入在自然环境中进行的一系列青少年和成人队列研究中， 辅之以良好控制的实验研究，可以进行因果推断。为了实现 如上所述，我们将利用人口危害模型（图 1），其中对人口的危害是由于 个人疾病风险和暴露人数。 OSUCERT 的主要研究领域 这将协助 FDA 纳入广告和营销的影响；认知和情感 对决策的影响；重点关注无烟烟草（ST）和双重用途；城乡兼顾 人群以增强普遍性；以及涵盖烟草使用者范围的协同研究 青少年到成人。我们中心将解决 FDA 一月份提出的 56 个研究重点中的 11 个， 2012年。