Interdisciplinary Anesthesiology Research Training Program

跨学科麻醉学研究培训计划

• 批准号: 9209650
• 负责人: Hemal H Patel
• 金额: $ 13.44万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9209650
• 关键词: Anesthesiology; Research Training; Training Programs

Anesthesiology is an interdisciplinary discipline that requires its practitioners to have a broad fund of knowledge that traverses pharmacology, physiology, and engineering with the ability to apply this knowledge in both controlled and emergency situations. In addition to providing trainees with exceptional clinical knowledge, the Anesthesiology Department as well as the larger academic community at the University of California, San Diego (UCSD), provides a world-class environment for the development of high quality training in research. Two particular basic science research strengths at UCSD include the Departments of Pharmacology and Engineering. Anesthesiologists including both basic scientists and clinicians have long standing interactions and collaborations with faculty in these two disciplines as the interests mirror the major clinical concerns of anesthesiology, the use of pharmacologic agents to best manage patients and to invent and create solutions that require engineering to enhance patient care. Our interactions and collaborations have spanned established faculty, junior physician scientist, fellows and residents. Thus, the primary goal of this T32 grant application is to formalize and take to the next level research training that has been occurring at UCSD and specifically in the Department of Anesthesiology with collaboration in Pharmacology and Engineering. This training grant will provide post-graduate trainees (MDs or MD/PhDs) with a 2-year research experience consisting of a broad focus on the basic molecular mechanisms of drug action and/or exploration of a variety of engineering disciplines. There is emphasis upon defining novel insights into mechanisms of drug action that can lead to development of therapeutic interventions and in applying engineering principles to create devices, model physiology and pathophysiology using mathematical and theoretical approaches, investigate biomaterials to facilitate non-invasive monitoring and generation of biometric data, etc. From a practical perspective, to achieve this overall goal, the training experience has two specific aims: i) expose the fellows to a culture of science and investigation present in the Department specifically and the campus broadly and ii) achieve competency in the allied elements of a research career, e.g. experimental design, data analyses, presentations, manuscript preparation and publication and how best to obtain research funding as well as lab management and job interview skills. Importantly, we strongly emphasize issues of collegiality and ethics in the research environment. In achieving our strong commitment to the development of the clinician scientist, our overriding mission is the training of the next generation of clinician scientists who have the foundation of knowledge and fundamental tools coupled with the passion and commitment to affect translational research.

麻醉学是一门跨学科学科，要求其从业者拥有广泛的知识基础 跨越药理学、生理学和工程学的知识，并能够将这些知识应用于 受控情况和紧急情况。除了为学员提供卓越的临床知识外， 加州大学圣路易斯分校麻醉学系以及更大的学术界 迭戈（加州大学圣地亚哥分校）为高质量研究培训的发展提供了世界一流的环境。 加州大学圣地亚哥分校的两个特殊的基础科学研究优势包括药理学系和 工程。包括基础科学家和临床医生在内的麻醉科医生有着长期的互动 以及与这两个学科的教师的合作，因为兴趣反映了主要的临床问题 麻醉学，使用药物来最好地管理患者并发明和创造解决方案 需要工程来加强患者护理。我们的互动与合作已跨越 已建立的教职人员、初级医师科学家、研究员和住院医生。因此，本次 T32 拨款的主要目标 申请的目的是将加州大学圣地亚哥分校正在进行的研究培训正式化并提升到一个新的水平 特别是在麻醉科与药理学和工程学合作。这 培训补助金将为研究生学员（医学博士或医学博士/博士）提供 2 年研究经验 包括广泛关注药物作用的基本分子机制和/或探索各种 工程学科。重点是定义对药物作用机制的新颖见解， 可以导致治疗干预措施的发展并应用工程原理来创建设备， 使用数学和理论方法建立生理学和病理生理学模型，研究 生物材料，以促进非侵入性监测和生物识别数据的生成等。 从长远来看，为了实现这一总体目标，培训经历有两个具体目标： i) 让学员接触 科学和调查文化在该系和整个校园中存在，ii) 获得研究职业相关要素的能力，例如实验设计、数据分析、 演示、手稿准备和出版以及如何最好地获得研究经费和实验室 管理和求职面试技巧。重要的是，我们强烈强调合作和道德问题 研究环境。为了实现我们对临床科学家发展的坚定承诺，我们 最重要的使命是培训下一代临床科学家，他们具有以下基础： 知识和基本工具加上影响转化研究的热情和承诺。