Interdisciplinary Anesthesiology Research Training Program

跨学科麻醉学研究培训计划

基本信息

批准号：
10555968
负责人：
Hemal H Patel
金额：
$ 17.13万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10555968
关键词：
Anesthesiology Research Training Training Programs

项目摘要

Abstract Anesthesiology is an interdisciplinary medical specialty requiring its practitioners to have a broad fund of knowledge, including pharmacology, physiology, and engineering and the ability to apply this knowledge in both controlled and emergency situations. In addition to providing trainees with exceptional clinical knowledge and skills, the Anesthesiology Department as well as the larger academic community at the University of California, San Diego (UCSD), provides a world-class environment for high quality training in research. Two particular basic science research strengths at UCSD include the Departments of Pharmacology and Engineering. Anesthesiologists including both basic scientists and clinicians have productive interactions and collaborations with faculty in these two disciplines. Thus, the primary goal of this renewal T32 grant application remains to train the next generation of clinician scientist in the Department of Anesthesiology to address important questions in the discipline by leveraging the potential interdisciplinary training available in collaboration with faculty in pharmacology and engineering. These interactions serve as guidance for our fellows; however, fellows with their mentoring team have the ability to work beyond, within, and in larger collaboratives to undertake research at the broadest level to involve as many disciplines necessary to adequately address the questions asked. This goal will continue to be facilitated by approaching primary questions in anesthesia with an interdisciplinary training focus; however, the program will remain flexible to expand research scope as the interests of fellows develop. This training grant will provide post-graduate trainees (MDs or MD/PhDs) with a 2-year research experience consisting of a broad focus on the basic molecular mechanisms of drug action and/or exploration of a variety of engineering disciplines. Emphasis will be on defining novel mechanisms of drug action for therapeutic interventions, applying engineering principles to create devices, model physiology and pathophysiology using mathematical and theoretical approaches, investigate biomaterials to facilitate non-invasive monitoring, and generation of biometric and blood derived biological data, among other projects to enhance human health and the patient experience. To achieve this overall goal, the training experience has two specific aims: i) expose fellows to a culture of science and investigation present in the Department specifically and the campus broadly and ii) achieve competency in the allied elements of a research career, e.g. experimental design, data analyses, presentations, manuscript preparation and publication and how best to obtain research funding as well as lab management and job interview skills. We strongly emphasize collegiality and ethics in the research environment. In achieving our strong commitment to the development of the clinician scientist, our overriding mission is the training of the next generation of clinician scientists who have the foundation of knowledge and fundamental tools coupled with the passion and commitment to affect translational research.

抽象的麻醉学是一门跨学科的医学专业，要求其从业者拥有广泛的知识知识，包括药理学、生理学和工程学，以及应用这些知识的能力受控情况和紧急情况。除了为学员提供卓越的临床知识之外和技能、麻醉学系以及大学更大的学术界加州圣地亚哥 (UCSD) 为高质量的研究培训提供了世界一流的环境。二加州大学圣地亚哥分校的基础科学研究优势包括药理学系和工程。包括基础科学家和临床医生在内的麻醉师之间进行了富有成效的互动，与这两个学科的教师合作。因此，本次更新 T32 拨款申请的主要目标仍然需要培训麻醉科的下一代临床科学家来解决通过利用潜在的跨学科培训来解决该学科中的重要问题与药理学和工程学教师的合作。这些互动可以作为我们的指导研究员；然而，研究员及其指导团队有能力在更大范围内、更大范围内工作合作进行最广泛的研究，涉及尽可能多的学科充分解决所提出的问题。通过接近初级教育将继续促进这一目标的实现以跨学科培训为重点的麻醉问题；然而，该计划将保持灵活性随着研究员兴趣的发展扩大研究范围。该培训补助金将提供研究生具有 2 年研究经验（广泛关注基础知识）的受训者（医学博士或医学博士/博士）药物作用的分子机制和/或各种工程学科的探索。强调将应用工程原理，定义用于治疗干预的药物作用的新机制使用数学和理论方法创建设备、模拟生理学和病理生理学，研究生物材料以促进非侵入性监测以及生物特征和血液来源的生成生物数据以及其他旨在增强人类健康和患者体验的项目。为了实现这一目标总体目标是，培训经历有两个具体目标：i) 让学员接触科学文化和 ii）在该部门和整个校园中进行调查，并获得以下方面的能力研究生涯的相关要素，例如实验设计、数据分析、演示、手稿准备和出版以及如何最好地获得研究经费以及实验室管理和工作面试技巧。我们强烈强调研究环境中的合作和道德。在实现我们的我们坚定致力于临床科学家的发展，我们的首要任务是培训临床科学家拥有基础知识和基本工具的下一代临床科学家充满热情并致力于影响转化研究。

项目成果

期刊论文数量（16）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Treatment of Bronchopleural and Alveolopleural Fistulas in Acute Respiratory Distress Syndrome With Extracorporeal Membrane Oxygenation, a Case Series and Literature Review.

DOI：
10.1097/cce.0000000000000393
发表时间：
2021-05
期刊：
Critical care explorations
影响因子：
0
作者：
Odish MF;Yang J;Cheng G;Yi C;Golts E;Madani M;Pollema T;Owens RL
通讯作者：
Owens RL

The Southern California Extracorporeal Membrane Oxygenation Consortium During the Coronavirus Disease 2019 Pandemic.

DOI：
10.1017/dmp.2021.179
发表时间：
2021-06-08
期刊：
Disaster medicine and public health preparedness
影响因子：
2.7
作者：
Odish M;Yi C;Eigner J;Kenner Brininger A;Koenig KL;Willms D;Lerum S;McCaul S;Boyd King A;Sutherland G;Cederquist L;Owens RL;Pollema T
通讯作者：
Pollema T

Implementation and Outcomes of a Mobile Extracorporeal Membrane Oxygenation Program in the United States During the Coronavirus Disease 2019 Pandemic.