7th Ataxia Investigators Meeting, From Bench to Bedside: Entering a New Era of Ataxia Therapies

第七届共济失调研究人员会议，从实验室到临床：进入共济失调治疗的新时代

• 批准号: 9471485
• 负责人: Gulin Oz
• 金额: $ 1万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-30 至 2018-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9471485
• 关键词: Address; Affect; Ataxia; Clinical Trials; Collaborations; Communication; Country; Deglutition; Development; Disease; Disease model; Economics; Elements; Ensure; Etiology; Europe; Eye Movements; Family; Foundations; Functional disorder; Funding; Future; Gait; Genetic; Goals; Human; Industry; International; Learning; Location; Molecular; Movement; Multi-Institutional Clinical Trial; Nature; Neuronal Dysfunction; Oral; Pathogenicity; Patients; Phase; Philadelphia; Prevalence; Rare Diseases; Readiness; Recruitment Activity; Research; Research Personnel; Route; Scientific Advances and Accomplishments; Scientist; Speech; Therapeutic; Time; Translational Research; United States; United States National Institutes of Health; Work; base; bench to bedside; design; dexterity; effective therapy; lectures; meetings; motor control; multi-site trial; multidisciplinary; nervous system disorder; novel therapeutics; posters; success; symposium; targeted treatment; therapeutic target; translational approach

PROJECT SUMMARY/ABSTRACT Ataxia, a disabling and frequently fatal neurological disorder, results from a wide variety of genetic and acquired etiologies. The 7th Ataxia Investigators' Meeting, “AIM 2018: From Bench to Bedside: Entering a New Era of Ataxia Therapies” will assemble an international roster of investigators to address the diverse causes of ataxia, better define the pathogenic basis of ataxia, explore routes to therapy, facilitate robust trials in ataxias, and help to establish future leaders in the ataxia research field. The conference will focus on the most recent scientific advances and emerging integrative approaches toward therapy, with the following objectives: 1) refine our understanding of cerebellar function and dysfunction; 2) develop and evaluate therapeutic strategies; 3) facilitate development of robust clinical trials in ataxias; 4) help to establish future leaders of ataxia research by facilitating the involvement of young investigators; and 5) bring trainees into contact with ataxia patients and their families. AIM 2018 will represent a critical mechanism to facilitate collaboration and discussion on ataxia research and therapeutic approaches, which is especially important now that the field is entering the phase of meaningful, multi-center clinical trials both in the United States and Europe. The AIM 2018 meeting, affiliated and overlapping with the annual meeting of the largest ataxia foundation in the country occurring at the same hotel, will maximize the impact of this meeting for scientists and patients alike.

项目摘要/摘要 共济失调是一种致命的且经常致命的神经系统疾病，是由多种遗传和 获得的病因。第七次共济失调调查人员的会议“ AIM 2018：从长凳到床头：进入 共济失调疗法的新时代”将组建一个国际调查人员的阵容，以解决潜水员 共济失调的原因，更好地定义了共济失调的致病基础，探索治疗途径，促进健壮的试验 在共济失调中，并有助于在共济失调研究领域建立未来的领导者。会议将重点放在 最新的科学进步和新兴的综合治疗方法，以下 目标：1）完善我们对小脑功能和功能障碍的理解； 2）开发和评估 治疗策略； 3）促进共济失调中强大的临床试验的发展； 4）帮助建立未来 共济失调研究的领导者通过促进年轻研究者的参与； 5）将受训者带入 与共济失调的患者及其家人接触。 AIM 2018将代表促进的关键机制 关于共济失调研究和治疗方法的协作与讨论，这尤其重要 该领域正在进入美国和 欧洲。 AIM 2018会议，会员和与最大共济失调的年度会议重叠 在同一家酒店发生的国家的基金会将最大化这次会议对科学家的影响 和患者。