Midcareer Investigator Award in Patient-Oriented Research for Dr. Gbenga Ogedegbe

Gbenga Ogedegbe 博士荣获以患者为导向的研究中的职业生涯中期研究员奖

• 批准号: 8974430
• 负责人: OLUGBENGA G. OGEDEGBE
• 金额: $ 12.43万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-12-15 至 2016-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8974430
• 关键词: Academia; Adoption; Affect; African American; Angiotensin-Converting Enzyme Inhibitors; Area; Award; Behavior Therapy; Behavioral; Behavioral Medicine; Biometry; Cardiovascular Diseases; Cardiovascular system; Caucasians; Characteristics; Chronic Disease; Clinical; Clinical Research; Clinical Trials; Clinical effectiveness; Communities; Data; Data Analyses; Data Set; Development; Disease Management; Educational workshop; Effectiveness; Effectiveness of Interventions; Electronic Health Record; Evaluation; Faculty; Funding; Goals; Grant; Health; Health behavior change; Hypertension; Interdisciplinary Study; Intervention; Investigator-Initiated Research; K-Series Research Career Programs; Laboratories; Maintenance; Medicine; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Midcareer Investigator Award in Patient-Oriented Research; Minority; Mission; National Heart, Lung, and Blood Institute; Outcome; Paper; Patients; Pharmacotherapy; Physicians; Population; Positioning Attribute; Process; Provider; Psychosocial Factor; Recruitment Activity; Research; Research Activity; Research Design; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Resources; Risk Reduction; SECTM1 gene; Science; Series; Sleep; Staging; Structure; Time; Training; Training Programs; Translating; Translations; Treatment Protocols; United States Agency for Healthcare Research and Quality; United States National Institutes of Health; Update; Work; Writing; base; behavior change; behavioral health; blood pressure regulation; candidate selection; cardiovascular health; cardiovascular risk factor; career; clinical practice; comparative effectiveness; design; disorder prevention; dissemination research; effectiveness research; evidence base; experience; health disparity; hypertension control; hypertension treatment; implementation research; investigator training; lifestyle intervention; medical schools; medication compliance; meetings; minority investigator; patient oriented research; programs; racial disparity; research data dissemination; role model; skills; summer institute

DESCRIPTION (provided by applicant): Racial disparities in hypertension-related outcomes between African Americans and whites are well documented. Despite the efficacy of patient and physician-targeted interventions, the effectiveness and dissemination of these approaches remain largely untested in African Americans. Thus there is urgent need to translate evidence-based hypertension improvement programs to clinical practices and community-based settings to reduce cardiovascular health disparities in African Americans. One way to realize this goal is to train investigators in dissemination and implementation research. Candidate: The candidate for this Mid-career Investigator Award in Patient-Oriented Research is Olugbenga Ogedegbe, MD, MPH. His research is focused on the development, dissemination and translation into clinical practices, evidence-based behavioral interventions targeted at reduction of racial disparities in hypertension-related outcomes. He is a leading expert in health disparities research and has an impressive track record of successful research and mentorship. He is the PI of an NHLBI-funded training grant designed to mentor minority investigators in Behavioral and Sleep Medicine research; and core faculty on several training programs including a T32 Training Program in Cardiovascular Sciences, and a K12 Training Program in Comparative Effectiveness Research. Career Objectives: This K24 Award will provide Dr. Ogedegbe with protected time to broaden his mentorship activities and fulfill the following career objectives: (1 To train new investigators in patient-oriented research focused on the development of evidence-based behavioral interventions targeted at cardiovascular risk reduction in minority populations; (2) To enhance his work in the development and evaluation of the effectiveness of evidence-based behavioral interventions targeted at different aspects of patient-level and physician-level barriers to BP control in minority populations; and (3) To enhance his mentoring skills in the area of comparative effectiveness research with a particular focus on evaluation of interventions targeted at cardiovascular risk reduction in minority populations. Research Plan: Dr. Ogedegbe has four R01 grants that evaluate in three clinical trials, the translation of evidence-based behavioral interventions into clinical practices and the evaluation of the comparative effectiveness of well-proven drug therapy for treatment of hypertension in African Americans compared to Caucasians. These studies will support the mentorship activities for this award and serve as the clinical laboratory for mentees to launch their research careers. Mentoring Plan: Dr. Ogedegbe will mentor new investigators in the context of his newly funded training grant in Behavioral and Sleep Medicine research. In addition, he proposes a series of didactic courses, tailored mentoring, and structured research experiences to increase the independence of his trainees' research careers. He will work with trainees at different stages of their career and from a variety of professional backgrounds, thus facilitating multidisciplinary research experience for the trainees.

描述（由申请人提供）：非裔美国人和白人之间高血压相关结果的种族差异有据可查。尽管针对患者和医生的干预措施有效，但这些方法的有效性和传播在非裔美国人中很大程度上尚未经过测试。因此，迫切需要将循证高血压改善计划转化为临床实践和社区环境，以减少非裔美国人的心血管健康差异。实现这一目标的一种方法是培训研究人员进行传播和实施研究。候选人：以患者为导向的研究领域职业生涯中期研究者奖的候选人是 Olugbenga Ogedegbe，医学博士、公共卫生硕士。他的研究重点是开发、传播和转化为临床实践，以及旨在减少高血压相关结果的种族差异的循证行为干预措施。他是健康差异研究领域的领先专家，在成功的研究和指导方面拥有令人印象深刻的记录。他是 NHLBI 资助的一项培训基金的 PI，该培训基金旨在指导少数族裔研究人员进行行为和睡眠医学研究；以及多个培训项目的核心教师，包括心血管科学 T32 培训项目和比较有效性研究 K12 培训项目。职业目标：该 K24 奖将为 Ogedegbe 博士提供受保护的时间，以扩大他的指导活动并实现以下职业目标：（1 培训新研究人员进行以患者为导向的研究，重点是开发针对心血管疾病的循证行为干预措施减少少数群体的风险；(2) 加强针对少数群体中患者层面和医生层面的血压控制障碍的循证行为干预措施的有效性的开发和评估；(3) ) 来增强他的比较有效性研究领域的指导技能，特别注重评估针对少数群体心血管风险降低的干预措施。 研究计划：Ogedegbe 博士拥有四项 R01 资助，用于评估三项临床试验，即基于证据的行为的转化。对临床实践进行干预，并评估经过充分证明的药物疗法治疗非裔美国人与白种人高血压的相对有效性。这些研究将支持该奖项的指导活动，并作为受指导者开展研究生涯的临床实验室。指导计划：Ogedegbe 博士将在其新资助的行为和睡眠医学研究培训资助的背景下指导新的研究人员。此外，他还提出了一系列教学课程、量身定制的指导和结构化的研究经验，以提高学员研究生涯的独立性。他将与职业生涯不同阶段的学员一起工作 各种专业背景，从而促进学员获得多学科研究经验。

项目成果

Treatment of hypertension in patients with coronary artery disease: a scientific statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension.

• DOI: 10.1161/cir.0000000000000207
• 发表时间: 2015-05-12
• 期刊: Circulation
• 影响因子: 37.8
• 作者: Rosendorff C;Lackland DT;Allison M;Aronow WS;Black HR;Blumenthal RS;Cannon CP;de Lemos JA;Elliott WJ;Findeiss L;Gersh BJ;Gore JM;Levy D;Long JB;O'Connor CM;O'Gara PT;Ogedegbe G;Oparil S;White WB;American Heart Association, American College of Cardiology, and American Society of Hypertension
• 通讯作者: American Heart Association, American College of Cardiology, and American Society of Hypertension

Do black patients with chronic kidney disease benefit equally from all blood pressure lowering agents?

• DOI: 10.1136/bmj.g142
• 发表时间: 2014-01-15
• 期刊: BMJ (Clinical research ed.)
• 作者: Ladapo JA;Ogedegbe G
• 通讯作者: Ogedegbe G

Unconscious bias and real-world hypertension outcomes: advancing disparities research.

无意识偏见和现实世界的高血压结果：推进差异研究。

• DOI: 10.1007/s11606-014-2849-2
• 发表时间: 2014
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: Ravenell,Joseph;Ogedegbe,Gbenga
• 通讯作者: Ogedegbe,Gbenga

Race/ethnicity moderates the relationship between chronic life stress and quality of life in type 2 diabetes.

• DOI: 10.1016/j.diabres.2015.01.025
• 发表时间: 2015-04
• 期刊: DIABETES RESEARCH AND CLINICAL PRACTICE
• 影响因子: 5.1
• 作者: Shallcross, Amanda J.;Ojie, Mary-Jane;Chaplin, William;Levy, Natalie;Odedosu, Taiye;Ogedegbe, Gbenga;Spruill, Tanya M.
• 通讯作者: Spruill, Tanya M.

Recognition and Management of Hypertension in Older Persons: Focus on African Americans.

• DOI: 10.1111/jgs.13672
• 发表时间: 2015-10
• 期刊: Journal of the American Geriatrics Society
• 影响因子: 6.3
• 作者: Still CH;Ferdinand KC;Ogedegbe G;Wright JT Jr
• 通讯作者: Wright JT Jr