An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer

电子健康干预措施可改善完成乳腺癌积极治疗的西班牙裔女性的症状负担和健康相关的生活质量

• 批准号: 9163035
• 负责人: BETINA YANEZ
• 金额: $ 16.76万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9163035
• 关键词: Address; Advanced Malignant Neoplasm; Affect; African American; Aftercare; Age; Belief; Breast; Breast Cancer Education; Breast Cancer Treatment; Breast Cancer survivor; Cancer Etiology; Cancer Patient; Cancer Survivor; Cardiovascular Diseases; Cause of Death; Cellular Phone; Cessation of life; Chicago; Communication; Coping Skills; Data; Diagnosis; Distress; Evaluation; Evidence based intervention; Face; Health; Health Services Accessibility; Healthcare; Hispanics; Insurance Coverage; Intervention; Intervention Studies; Knowledge; Longitudinal Studies; Malignant Neoplasms; Methodology; Methods; Minority Groups; Names; Not Hispanic or Latino; Outcome; Participant; Patient Outcomes Assessments; Patients; Persons; Phase; Psychiatric Social Work; Randomized; Recruitment Activity; Reporting; Resources; Sample Size; Services; Socioeconomic Factors; Staging; Survivors; Symptoms; Technology; Testing; Time; Underserved Population; Woman; Work; abstracting; active method; base; breast cancer diagnosis; cancer diagnosis; cancer therapy; cost; critical period; depressive symptoms; design; eHealth; ethnic minority population; evidence base; experience; handheld mobile device; health equity; health related quality of life; improved; innovation; malignant breast neoplasm; novel; patient population; primary outcome; psychoeducation; psychoeducational; psychosocial; randomized trial; reduce symptoms; secondary outcome; skills; socioeconomics; stress management; survivorship; symptomatic improvement; therapy design; tool; usability

An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer Abstract Among Hispanics, the largest and fastest growing ethnic minority group in the U.S., cancer is the leading cause of death whereas cardiovascular disease is the leading cause of death for African Americans and non- Hispanic Whites (NHWs). Hispanics also experience substantially lower rates of 5-year cancer-specific survival relative to non–Hispanic Whites (NHWs). Hispanic cancer patients in the U.S. also report significantly worse cancer-related symptom burden and health-related quality of life (HRQOL) than NHWs, even after adjusting for socioeconomic factors. Despite this, very few randomized, intervention studies have specifically targeted cancer-related symptom burden and HRQOL outcomes among Hispanic women, especially during the period at the end of active treatment which is a critical period to intervene to provide skills and tools to assist with this transition. Innovative approaches to providing interventions such as Smartphone technology are especially important for this patient population. Ubiquitous Smartphone use among ethnic minorities in the US provide a unique opportunity to implement a pragmatic technology- and evidence-based psychosocial intervention that overcomes some access to care barriers as well as time and logistical constraints. Furthermore, given that Hispanics own Smartphones and seek health information online from a mobile device at similar or higher rates than other groups in the U.S., Smartphone interventions offer an opportunity to overcome obstacles to accessing resources and services that can be culturally informed and provide skills to improve symptom burden and HRQOL. This study aims to create and evaluate Mi Guía (My Guide), a culturally informed eHealth psychoeducational and psychosocial intervention for English or Spanish-speaking Hispanic women completing treatment for breast cancer. Mi Guía is grounded in evidence-based paradigms to improve our Primary Outcomes: Cancer-Related Symptom Burden and HRQOL and our Secondary Outcomes: usability and markers of Mi Guía use. We propose a two-phase study to develop our Smartphone-based intervention that can be disseminated to cancer survivors at a relatively low cost. We will use innovative methodology; MOST framework that will allow us to achieve both optimization and evaluation of Mi Guía by determining which single components or combination of components in Mi Guía affect our outcomes. Study components (one component on breast cancer psychoeducation, two psychosocial evidence-based components relevant to Hispanic BCS) will be paired with personal tele-coaching among BCS. Our Aims are: Aim 1:(Phase 1): Create Mi Guía, an eHealth intervention designed to improve cancer-related symptom burden and HRQOL. Aim 2: (Phase 2): Optimize components for Mi Guía through a 9-week randomized trial to evaluate three evidence- based intervention components relevant to Hispanic BCS. It is hypothesized that each single intervention component will improve cancer-related symptom burden and HRQOL and that combined intervention components will have a greater effect on our outcomes than single components.

改善症状负担和健康相关生活质量的电子健康干预措施 完成乳腺癌积极治疗的西班牙裔女性 抽象的 在美国最大、增长最快的少数族裔群体西班牙​​裔中，癌症是头号杀手 死亡原因，而心血管疾病是非裔美国人和非裔美国人的主要原因 西班牙裔白人 (NHW) 的 5 年癌症特异性生存率也显着降低。 相对于非西班牙裔白人 (NHW)，美国的西班牙裔癌症患者的情况也明显较差。 即使在调整后，癌症相关症状负担和健康相关生活质量 (HRQOL) 仍高于 NHW 尽管如此，很少有随机干预研究专门针对 西班牙裔女性癌症相关症状负担和 HRQOL 结果，尤其是在此期间 在积极治疗结束时，这是进行干预以提供技能和工具来协助这一点的关键时期 提供智能手机技术等干预措施的创新方法尤其重要。 对于美国少数民族患者来说，智能手机的普遍使用提供了一个重要的途径。 实施基于实用技术和证据的心理社会干预的独特机会 此外，克服了获得护理的一些障碍以及时间和后勤限制。 西班牙裔人拥有智能手机，并以相似或更高的速度通过移动设备在线寻求健康信息 与美国其他团体相比，智能手机干预提供了克服障碍的机会 获取可以了解文化并提供改善症状的技能的资源和服务 本研究旨在创建和评估 Mi Guía（我的指南），一种文化信息化的电子医疗保健。 对讲英语或西班牙语的西班牙裔妇女进行心理教育和社会心理干预 Mi Guia 的治疗基于循证范例，以改善我们的初级保健。 结果：癌症相关症状负担和 HRQOL 以及我们的次要结果：可用性和 我们提出了一项两阶段研究来开发基于智能手机的干预措施。 可以以相对较低的成本传播给癌症幸存者；我们将使用创新的方法； 该框架将使我们能够通过确定哪个单一的来实现 Mi Guia 的优化和评估 Mi Guía 中的成分或成分组合会影响我们的研究结果（其中之一。 乳腺癌心理教育的心理成分，与相关的两个社会证据为基础的成分 西班牙裔 BCS）将与 BCS 之间的个人远程辅导相结合。我们的目标是： 目标 1：（第 1 阶段）：创建。 Mi Guía，一种电子健康干预措施，旨在改善癌症相关症状负担和 HRQOL 目标 2： （第 2 阶段）：通过为期 9 周的随机试验优化 Mi Guia 的成分，以评估三个证据 - 与西班牙裔 BCS 相关的干预措施。 成分将改善癌症相关症状负担和 HRQOL，并且联合干预 与单个组件相比，组件对我们的结果产生更大的影响。