American Indian - Alaska Native Clinical and Translational Research Center (AI-AN CTRC)

美洲印第安人 - 阿拉斯加原住民临床和转化研究中心 (AI-AN CTRC)

• 批准号: 8946928
• 负责人: BERT Brandon BOYER
• 金额: $ 429.8万
• 依托单位: MONTANA STATE UNIVERSITY - BOZEMAN
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2021-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8946928
• 关键词: Address; Alaska; Alaska Native; American Indians; Applications Grants; Area; Basic Science; Behavioral; Biostatistics Core; Cause of Death; Center for Translational Science Activities; Clinical; Clinical Investigator; Clinical Research; Collaborations; Communities; Data; Death Rate; Development; Doctor of Philosophy; Education; Epidemiology; Ethnic group; Evaluation; Face; Foundations; Funding; Funding Agency; Goals; Health; Health Priorities; Healthcare; Home environment; Institution; Interdisciplinary Study; Mentors; Methodology; Monitor; Montana; Native-Born; Pilot Projects; Population; Process; Race; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Services; Training; Training Support; Translational Research; United States National Institutes of Health; Universities; Work; Writing; career; cohort; community building; community college; design; experience; health disparity; improved; interest; medical schools; meetings; member; outreach; programs; public health relevance; research and development; social; training opportunity; tribal community; tribal health; working group

 DESCRIPTION (provided by applicant): The American Indian-Alaska Native Clinical and Translational Research Center (AI-AN CTRC) has the goal of developing the capacity of Montana and Alaska to address the unique problems these state's Native communities face in health disparities. AN-AI-AN CTRC will increase numbers of, train, support, and mentor investigators from AK and MT through research service cores and funding of community engagement research projects to address health disparities in MT's and AK's Native communities. Montana State University will be the home institution for this project and will partner with Blackfeet Community College (BCC), University of Montana (UM), University of Alaska Fairbanks (UAF), University of Alaska Anchorage (UAA), Alaska Native Tribal Health Consortium (ANCTH) of Anchorage, and Southcentral Foundation (SCF) of Anchorage. BCC, ANCTH, and SCF are owned and managed by tribal communities. To realize these goals, AI-AN CTRC will: 1. Strengthen Montana's and Alaska's clinical and translational research infrastructure through continued development of shared facilities, intellectual resources, research collaborations, focused working groups, and training opportunities. MT and AK established investigators will develop 5 research cores which include: the Community Engagement and Outreach Core (CEOC), which will guide investigators through the process of community engagement research; the Professional Development Core (PDC), which will train and mentor investigators in clinical health disparities research; the Pilot Project Program Core (PPPC) will fund pilot research projects to facilitate the development of fundable programs by new clinical investigators; the Research Design, Epidemiology and Biostatistics Core (RDEBC), will provide expertise in epidemiological and statistical methodologies needed at all levels of the clinical research process; and the Tracking and Evaluation Core (TEC) which will constantly monitor the progress of the center and its components. 2. Increase numbers, mentor, and develop the careers of clinical investigators in Native health disparities research in Montana and Alaska. This will be accomplished by developing the research capacity of new clinical investigators, developing interest of scientists not already working in Native health to build programs in this area, developing the ability of established clinical investigators in Native healt research to form interdisciplinary research teams including basic science researchers. 3. Expand and support sustainable and culturally responsible community engagement research that will mitigate health disparities in Montana's and Alaska's Native communities. The AI-AN CTRC will support MT and AK investigators to establish relationships with Native communities, build research capacity in the communities, and generate preliminary data required for grant proposals to funding agencies such as NIH. This will result in sustainable programs in AK and MT that will result in improved health of these state's Native communities.

 描述（由申请人提供）：美洲印第安人-阿拉斯加原住民临床和转化研究中心 (AI-AN CTRC) 的目标是发展蒙大拿州和阿拉斯加的能力，以解决这些州原住民社区在健康差异方面面临的独特问题。 AN -AI-AN CTRC 将通过研究服务核心和资助社区参与研究项目，增加 AK 和 MT 调查人员的数量、培训、支持和指导，以解决 MT 和 AK 土著人的健康差异蒙大拿州立大学将成为该项目的主办机构，并将与黑脚社区学院 (BCC)、蒙大拿大学 (UM)、阿拉斯加大学费尔班克斯分校 (UAF)、阿拉斯加安克雷奇大学 (UAA) 和阿拉斯加原住民部落合作。安克雷奇健康联盟 (ANCTH) 和安克雷奇中南基金会 (SCF) 由部落社区拥有和管理。为了实现这些目标，AI-AN CTRC 将： 1. 通过持续开发共享设施、智力资源、研究合作、重点工作组和培训机会，加强蒙大拿州和阿拉斯加州的临床和转化研究基础设施 MT 和 AK 建立的研究人员将开发 5 个研究核心，其中包括：社区参与和外展。核心（CEOC），将指导研究人员完成社区参与研究的过程；专业发展核心（PDC），将培训和指导临床健康差异研究的研究人员；试点项目计划核心（PPPC）将资助试点；促进新临床研究人员开发可资助项目的研究项目；研究设计、流行病学和生物统计学核心（RDEBC），将提供各级所需的流行病学和统计方法方面的专业知识； 临床研究流程；以及跟踪和评估核心（TEC），该核心将不断监测该中心及其组成部分的进展。 2. 增加蒙大拿州和阿拉斯加土著健康差异研究的临床研究人员的数量、指导和职业发展。这将通过新的临床研究人员的研究开发能力、培养尚未从事本土健康工作的科学家的兴趣来实现该领域的项目、发展本土健康研究中已建立的临床研究人员形成包括基础科学在内的跨学科研究团队的能力来实现3. 扩大和支持可持续发展。 AI-AN CTRC 将支持 MT 和 AK 调查人员与原住民社区建立关系，建立社区的研究能力，并生成拨款所需的初步数据。向 NIH 等资助机构提出提案，这将导致 AK 和 MT 的可持续计划，从而改善这些州原住民社区的健康状况。