Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer

增强亲密关系的夫妻对局限性前列腺癌的干预

• 批准号: 8700724
• 负责人: Sharon L Manne
• 金额: $ 11.33万
• 依托单位: RBHS -CANCER INSTITUTE OF NEW JERSEY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8700724
• 关键词: Address; Adverse effects; Attention; Back; Characteristics; Client satisfaction; Clinical; Communication; Couples; Data; Diagnosis; Distress; Educational process of instructing; Emotional; Erectile dysfunction; Extravasation; Family; Goals; Health; Individual; Intervention; Length; Malignant Neoplasms; Malignant neoplasm of prostate; Mediating; Modeling; Outcome; Participant; Patients; Pilot Projects; Play; Population Intervention; Problem Solving; Psychological adjustment; Quality of life; Randomized; Randomized Clinical Trials; Reporting; Research; Role; Sex Functioning; Staging; Surveys; Testing; Time; Uncertainty; Work; base; brief intervention; communication behavior; comparative efficacy; improved; innovation; intimate behavior; men; oncology; psychologic; psychological distress; psychosocial; satisfaction; self esteem; skills; stress management; treatment as usual; treatment effect; urinary

DESCRIPTION (provided by applicant): The diagnosis and treatment of localized prostate cancer can reduce the quality of life for both patient and partner. Our preliminary studies as well as the work of others suggest that couples' communication and intimacy play a role in the psychological and relationship functioning of both patient and partner. These results suggest that enhancing intimacy via improvements in the communication strategies couples utilize may be a prime target for psychological intervention. We have developed an Intimacy- Enhancing Couples' Intervention (IEC) and tested it against a Usual care control (UC) in a small randomized clinical trial. The primary goal of IEC is to teach couples relationship-enhancing communication skills and bolster relationship intimacy. Preliminary results suggested that IEC reduced patient and partner distress and improved communication and intimacy. The goal of the proposed study is to conduct a larger scale trial to evaluate IEC's efficacy against an attention control (a General Health and Wellness Intervention; GHW) and to evaluate moderators and mechanisms for the treatment's effects. 469 men diagnosed with localized prostate cancer and their partners will be randomly assigned to IEC, GHW, or UC. Participants will complete surveys pre-intervention, 5 weeks, 12 weeks, and six months post-baseline. The aims are: 1) To evaluate the impact of an IEC versus a GHW and UCl on patient and partner psychological and relationship outcomes. 2) To determine whether relationship length, pre-intervention marital satisfaction, and men's pre-intervention traditional masculinity moderate the effects of IEC on couples' psychological and relationship outcomes. IEC will have a stronger impact on patient and partner psychological and relationship functioning among patients and partners married a longer period of time, patients and partners reporting lower pre-intervention levels of marital satisfaction, and among patients reporting higher levels of traditional masculinity; 3) To evaluate whether IEC has an effect on couples' communication and intimacy when compared with GHW and UC, and to determine whether changes in relationship communication and intimacy mediate changes in couples' psychological and relationship outcomes.

描述（由申请人提供）：局限性前列腺癌的诊断和治疗会降低患者和伴侣的生活质量。我们的初步研究以及其他人的工作表明，夫妻的沟通和亲密关系在患者和伴侣的心理和关系功能中发挥着重要作用。这些结果表明，通过改善夫妻使用的沟通策略来增强亲密感可能是心理干预的主要目标。我们开发了一种增强亲密关系的干预措施（IEC），并在一项小型随机临床试验中针对常规护理对照（UC）对其进行了测试。 IEC 的主要目标是教授夫妻增进关系的沟通技巧并增强关系的亲密程度。初步结果表明，IEC 减少了患者和伴侣的痛苦，改善了沟通和亲密关系。拟议研究的目标是进行更大规模的试验，以评估 IEC 对注意力控制（一般健康和保健干预措施；GHW）的功效，并评估治疗效果的调节因素和机制。 469 名被诊断患有局限性前列腺癌的男性及其伴侣将被随机分配到 IEC、GHW 或 UC。参与者将在干预前、基线后 5 周、12 周和 6 个月完成调查。目的是： 1) 评估 IEC 与 GHW 和 UCl 对患者和伴侣心理和关系结果的影响。 2) 确定关系长度、干预前的婚姻满意度和干预前男性的传统男性气质是否会调节IEC对夫妻心理和关系结果的影响。 IEC将对结婚时间较长的患者和伴侣、报告干预前婚姻满意度较低的患者和伴侣以及报告传统男性气质水平较高的患者和伴侣的心理和关系功能产生更大的影响； 3）与GHW和UC相比，评估IEC是否对夫妻沟通和亲密关系产生影响，并确定关系沟通和亲密关系的变化是否介导夫妻心理和关系结果的变化。