Community Interactions Outreach - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells

社区互动外展 - 正常和患病 iPS 细胞的神经元和神经胶质细胞特征

• 批准号: 9124944
• 负责人: STEVEN M FINKBEINER
• 金额: $ 2万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9124944
• 关键词: Address; Adult; Amyotrophic Lateral Sclerosis; Area; Autopsy; Bioinformatics; Biological; Cell Line; Cells; Child; Clinical; Clinical Data; Collaborations; Communities; Computer software; Computers; Data; Data Analyses; Data Set; Databases; Development; Discipline; Disease; Educational workshop; Ensure; Foundations; Generations; Genes; Genetic; Genomics; Goals; Huntington Disease; Informatics; Intelligence; Knowledge; Link; Mentors; Methodology; Mind; Network-based; Neurons; Neurosciences; Online Systems; Pathway interactions; Pharmaceutical Preparations; Proteomics; Research; Research Infrastructure; Research Personnel; Resources; Role; Running; Sampling; Scientist; Series; Signal Pathway; Software Tools; Source; Spinal Muscular Atrophy; Stem cells; Structure; Technology; Tissues; Ursidae Family; analytical tool; base; computerized tools; data access; design; experience; induced pluripotent stem cell; innovation; nervous system disorder; outreach; programs; success; symposium; tool; tool development; wiki

Community Interactions & Outreach Component The NeuroLINCS Community project will plan to provide resources and tools for a broad user base of basic and clinical scientists. It has a structure to facilitate access to the various genetic and proteomic data sets, the signatures created, and the analysis tools. It is designed to be directed to researchers at the bench, clinicians developing biological disease readouts and those in computational roles. It will incorporate an assessment to demonstrate the utility of the generated resources, methodologies, and analytical tools to LINCS and non-LINCS scientific community. Importantly, it will develop and implement a plan to bring in external collaborators who may have data sets that bear on the development of cell signatures. There is an extensive plan to develop workshops, tutorials, and symposia in conjunction with the use of innovative online technologies for disseminating information to target the major LINCS goals. Finally it will develop bidirectional links with the neuroscience clinical and basic community through a series of collaborations with large National clinical data and tissue-based networks.

社区互动和外展部分 NeuroLINCS 社区项目将计划为基础和临床科学家的广泛用户群提供资源和工具。它的结构有助于访问各种遗传和蛋白质组数据集、创建的签名和分析工具。它旨在面向实验室研究人员、开发生物疾病读数的临床医生以及从事计算工作的人员。它将纳入一项评估，以向 LINCS 和非 LINCS 科学界展示所生成的资源、方法和分析工具的效用。重要的是，它将制定并实施一项计划，引入可能拥有与细胞特征开发有关的数据集的外部合作者。我们有一项广泛的计划来举办研讨会、教程和研讨会，并结合使用创新的在线技术来传播信息，以实现 LINCS 的主要目标。最后，它将通过与大型国家临床数据和组织网络的一系列合作，与神经科学临床和基础社区建立双向联系。