Diet quality and cardiometabolic disparities among Latino ethnic subgroups

拉丁裔族群之间的饮食质量和心脏代谢差异

• 批准号: 9108165
• 负责人: JOSIEMER MATTEI
• 金额: $ 14.16万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-15 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9108165
• 关键词: Accounting; Adult; Advisory Committees; Affect; Ankle; Area; Attitude; Behavior Therapy; Belief; Blood Pressure; Boston; Cardiovascular Diseases; Cardiovascular system; Central American; Chronic Disease; Clinic; Collaborations; Communities; Community Health Centers; Community Trial; Cuban American; Data; Diet; Diet Habits; Dietary Intervention; Disease; Doctor of Philosophy; Educational Intervention; Epidemiologic Methods; Epidemiology; Ethnic Origin; Ethnic group; Faculty; Food; Funding; Goals; Grant; Growth; Health; Healthy Eating; High Prevalence; Hispanic Community Health Study/Study of Latinos; Hispanics; Inflammatory; Institution; Interleukin-6; Intervention; Island; K-Series Research Career Programs; Knowledge; Latin America; Latino; Leadership; Life; Lipids; Longitudinal Studies; Mentors; Metabolic; Metabolic Diseases; Metabolic syndrome; Methods; Mexican; Minority Groups; Monitor; National Heart, Lung, and Blood Institute; Non-Insulin-Dependent Diabetes Mellitus; Nutritional; Obesity; Outcome; Participant; Perception; Pilot Projects; Population; Positioning Attribute; Prevalence; Public Health; Public Health Schools; Puerto Rican; Puerto Rico; Recruitment Activity; Research; Research Personnel; Research Training; Resources; Risk; Risk Factors; Role; Shapes; Solid; South American; Structure; Study of Latinos; Subgroup; Surface; TNF gene; Training; Training Programs; Translating; Translations; United States; Variant; Work; abstracting; aged; base; burden of illness; cardiometabolic risk; cardiovascular disorder risk; cardiovascular health; career; career development; cohort; community intervention; design; health disparity; improved; indexing; metabolic profile; nutrition; nutrition education; nutritional epidemiology; pilot trial; programs; racial and ethnic disparities; tool

DESCRIPTION (provided by applicant): The overall goal for this application for a NHLBI-K01 Faculty Diversity Mentored Career Development Award is to provide the candidate, Josiemer Mattei, PhD, MPH, with indispensable training to become an independent researcher in nutrition and cardio-metabolic disparities in Latinos, through epidemiological and intervention projects. These have been constructed along a comprehensive training program facilitated by a team of expert mentors in nutritional epidemiology, cardiovascular health, and community interventions. Responding to the staggering prevalence of cardiovascular disease (CVD) and other chronic disease in Latinos living in the United States (US), and to the limited studies on the dietary habits and cultural beliefs that may contribute to those disparities, the research aims are to (1) to identify diet quality indices within Latino ethnic subgroups in the US and to evaluate associations of such indices with traditional and emerging CVD risk factors within ethnicity, (2) to contrast diet quality of Puerto Ricans in the mainland US versus the island, and assess how it is associated with long-term cardio-metabolic factors; and (3) to assess deep-cultural factors (core beliefs and influences) related to diet and disease and determine efficacy of a pilot intervention based on such components for Latino subgroups on improving diet quality. Analyses for the first two aims will be conducted using data from the national Hispanic Community Health Study/Study of Latinos, the Boston Puerto Rican Health Study, and the San Juan Obese Adult Longitudinal Study in Puerto Rico. Latino multiethnic adults will be recruited for the mixed-methods formative and pilot studies to be conducted at the South End Community Health Center in Boston, MA. To match the scope of the proposed scientific work, this proposal includes five career-development and training areas: (1) research expertise through the proposed aims, (2) coursework in advanced epidemiological methods, and behavioral and community intervention methods, (3) multiple career-building activities to acquire essential tools for leadership and professional growth, as well as dissemination and translation of findings, (4) continued mentoring and monitoring by an outstanding team of senior mentors and an advisory committee; and (5) a detailed plan to expand grant support and collaborations with various national institutions. This K01 project will compellingly impact public health by bridging the gap in knowledge of traditional diet quality of specific Latino groups and how these may shape racial and ethnic disparities in CVD risk factors. The work will provide preliminary data to support longitudinal studies on diet and disease, and full-scale community trials on improving diet quality to reduce disease burden among Latinos. The project builds upon exceptional resources and mentoring at the candidate's institution (Harvard School of Public Health) and partnering organizations, to train her in key new areas, bolster applications for competitive funding, disseminate findings among researchers and the wider community, augment faculty diversity, and attain research independence. (End of Abstract)

描述（由申请人提供）：该申请的NHLBI-K01教师多样性的总体目标是为候选人提供候选人Josiemer Mattei博士，MPH，MPH，并通过在拉丁美洲人的营养和室内代谢室方面的独立培训，以成为独立的营养和心脏代谢差异。这些是在营养流行病学，心血管健康和社区干预方面的专家指导团队促进的全面培训计划中构建的。 应对居住在美国的拉丁裔（美国）中心血管疾病（CVD）和其他慢性疾病的惊人患病率（美国），以及对可能有助于这些差异的饮食习惯和文化信念的有限研究，研究目的是（1）在我们的饮食质量指数中识别出在我们的饮食质量指数中的饮食质量指标，以识别我们的饮食质量指数，以识别我们的饮食质量指标。种族，（2）在美国大陆与岛上的波多黎各人的饮食质量相比，并评估其与长期心脏代谢因素的相关性； （3）评估与饮食和疾病相关的深文因素（核心信念和影响），并根据该拉丁裔亚组对提高饮食质量的这种组成部分确定试验干预的功效。对前两个目标的分析将使用来自国家西班牙裔社区健康研究/拉丁美洲人研究，波士顿波多黎各人健康研究和波多黎各的圣胡安肥胖成人纵向研究的数据进行。将在马萨诸塞州波士顿的南端社区卫生中心进行的混合方法和试点研究招募拉丁裔多种族成年人。为了符合拟议的科学工作的范围，该提案包括五个职业发展和培训领域：（1）通过拟议的目标进行研究专业知识，（2）高级流行病学方法的课程以及行为和社区干预方法，（3）多个职业生涯建立了多个职业生涯的活动，以获得领导和专业成长的基本工具，并进行一定的领导力，以及一定的效果，以及融合的效果，（4），（4），（4），以及融合的效果，（4），（4），（4）及其融合（4），（4）的效果（4）（4）。咨询委员会； （5）扩大与各个国家机构的赠款支持和合作的详细计划。这个K01项目将通过弥合特定拉丁裔群体的传统饮食质量的差距以及这些如何影响CVD风险因素中的种族和种族差异来影响公共卫生。这项工作将提供初步数据，以支持有关饮食和疾病的纵向研究，以及有关提高饮食质量的全面社区试验 减轻拉丁裔疾病负担。该项目建立在候选人机构（哈佛公共卫生学院）和合作组织的卓越资源和指导的基础上，以在关键的新领域进行培训，增强竞争资金的申请，在研究人员和更广泛的社区之间传播发现，增强教师多样性的多样性和获得研究独立性。 （抽象的结尾）