Shared Resource: Northwest BioTrust

共享资源：西北生物信托

• 批准号: 8804785
• 负责人: STEPHEN C. SCHMECHEL
• 金额: $ 73.98万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-02-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8804785
• 关键词: Authorization documentation; Biological Sciences; Blood; Body Fluids; Cancer Center Support Grant; Child; Clinical; Code; Collaborations; Collection; Data; Development; Diagnostic; Ensure; Fee-for-Service Plans; Funding; Grant; Health Sciences; Institutes; Institutional Review Boards; Laboratories; Link; Malignant Neoplasms; Medical Education; Medicine; Mission; Pathology; Public Health; Research; Research Personnel; Resource Sharing; Resources; Role; Sampling; Services; Specimen; System; Therapeutic; Tissue Banking; Tissue Banks; Tissues; Washington; Work; abstracting; anticancer research; biomedical informatics; cost effective; human tissue; innovation; prospective; repository; research study; translational health science; virtual

Northwest BioTrust Shared Resource Project Summary/Abstract NWBioTrust (NWBT) is a new established resource that represents the maturation of the Developing Tissue Bank Shared Resource currently funded by the Cancer Center Support Grant (CCSG). The CCSG, as well as two major grants totaling $6.75M from Washington State's Life Sciences Discovery Fund (LSDF), funded much of the early developmental work of NWBT. NWBT is the result of a successful collaboration between the UW departments of Pathology, Laboratory Medicine, and Biomedical Informatics and Medical Education (BIME), the UW Institute of Translational Health Sciences (local CTSA), FHCRC, SCCA and Children's. The mission of NWBT is to provide reliable and cost-effective access to high-quality human tissue, blood and other body fluid samples, and associated clinical and specimen annotation data, for innovative diagnostic, therapeutic and public health sciences cancer research. The resource provides the following services: � Prospective collection of annotated research-only tissue, blood, and other specimens; � High-throughput collections of annotated remnant diagnostic materials; and � Identification of existing annotated repository samples using a Virtual Biospecimen Discovery (VBD) system. NWBT provides an important role to ensure that the well established Consortium cancer repositories acquire and maintain sufficient biospecimens to support a wide range of research studies. NWBT also staffs a fee-for- service office whereby researchers may extract EMR-derived data which may be linked to specimens (either identified, or de-identified via NWBT sample codes, depending on IRB permissions).

西北生物信托共享资源 项目概要/摘要 NWBioTrust (NWBT) 是一种新建立的资源，代表着发育组织的成熟 世行共享资源目前由癌症中心支持补助金 (CCSG) 以及 CCSG 资助。 来自华盛顿州生命科学发现基金 (LSDF) 的两项总计 675 万美元的重大资助 NWBT 的早期开发工作是威斯康星大学之间成功合作的结果。 病理学、检验医学、生物医学信息学和医学教育 (BIME) 系， 威斯康星大学转化健康科学研究所（当地 CTSA）、FHCRC、SCCA 和儿童基金会。 NWBT旨在提供可靠且具有成本效益的获取高质量人体组织、血液和其他体液的途径 样本以及相关的临床和样本注释数据，用于创新的诊断、治疗和 该资源提供以下服务： � 前瞻性收集带注释的研究用组织、血液和其他标本； � 高通量收集带注释的残留诊断材料；以及 使用虚拟生物样本发现（VBD）识别现有带注释的存储库样本 系统。 NWBT 在确保完善的联盟癌症存储库获得 并维持足够的生物样本以支持广泛的研究，NWBT 还收取费用。 研究人员可以在服务办公室提取可能与样本相关联的 EMR 衍生数据（ 通过 NWBT 示例代码进行识别或取消识别，具体取决于 IRB 权限）。