Center for Targeted Therapeutics

靶向治疗中心

• 批准号: 8885848
• 负责人: IGOR B RONINSON
• 金额: $ 220.05万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-10 至 2019-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8885848
• 关键词: Center; Targeted; Therapeutics

DESCRIPTION (provided by applicant): The principal goal of the proposed Center for Targeted Therapeutics (CTT), a Center of Biomedical Research Excellence (COBRE) at the University of South Carolina (USC), is to attract and foster the professional development of talented junior scientists, who are motivated to make a difference in the treatment of serious diseases. The CTT will be located at the SC College of Pharmacy (SCCP) at the University of South Carolina (USC) and the Medical University of South Carolina (MUSC), with one of the target faculty at the USC School of Medicine (SOM). The Center operations include four research projects led by four target junior faculty members (two at USC-SCCP, one at MUSC-SCCP and one at USC-SOM), with expertise in functional genomics, drug discovery, neuroscience and nanoparticle drug delivery. The Program will also include three resource cores: the Functional Genomics Core (USC-SCCP), the Synthetic Chemistry and Drug Discovery Core (MUSC-SCCP) and the Microscopy and Flow Cytometry Core (USCSCCP), each managed by a Director and a co-Director, who will provide scientific and intellectual advice in project development, along with technological support. Each of the projects will be working with each of the cores, except that one project, based at MUSC, will not utilize the Microscopy and Flow Cytometry core at USC. The CTT will take advantage of the existing integration between USC and MUSC in the South Carolina College of Pharmacy, which is in the unique position of being shared between the two Universities, with strong components on both campuses, and a well-developed system of video communication that allows for seamless communication and sharing of teaching and research programs. The CTT will be well-positioned to take full advantage of the resources of both institutions, where drug discovery and translational research are strong priorities, and also interface with IDeA programs already in place. The CTT umbrella will encompass several scientific areas critical for targeted therapeutics and spanning multiple diseases among which are cancer and neurologic disorders that are particularly relevant to the South Carolina population.

描述（由申请人提供）：拟议的目标治疗中心（CTT）的主要目标是南卡罗来纳大学（USC）的生物医学研究中心（COBRE）（COBRE）（USC），是为了吸引和促进才华横溢的初级科学家的专业发展，他们有动力在严重疾病的治疗中有所帮助。 CTT将位于南卡罗来纳大学（USC）和南卡罗来纳州医科大学（MUSC）的SC药学学院（SCCP），并设有USC医学院（SOM）的目标教师之一。该中心运营包括四个由四名目标初级教职员工领导的研究项目（USC-SCCP的两名在MUSC-SCCP，一个在USC-SOM），具有功能基因组学，药物发现，神经科学和纳米粒子药物的专业知识。该程序还将包括三个资源核心：功能基因组学核心（USC-SCCP），合成化学和药物发现核心（MUSC-SCCP）以及显微镜和流式细胞仪核心（USCSCCP），每个核心（USCSCCP）由董事和共同导演管理，他们将在项目开发方面提供科学和知识的建议以及技术支持。每个项目都将与每个核心一起工作，除了一个位于MUSC的一个项目将不会利用USC的显微镜和流式细胞仪核心。 CTT将利用南卡罗来纳州药房中USC和MUSC之间现有的整合，这是两所大学之间共享的独特位置，在两个校园中都具有强大的组成部分，并且具有完善的视频交流体系，可以实现无缝的沟通和教学和研究计划的无缝沟通和分享。 CTT将充分利用这两个机构的资源，在这些机构的资源中，药物发现和转化研究是强大的优先事项，并且与已经到位的Idea计划交往。 CTT雨伞将涵盖对靶向治疗至关重要的几个科学领域，并涵盖多种疾病，其中包括癌症和与南卡罗来纳州人群特别相关的神经系统疾病。