Animal Barrier

动物屏障

基本信息

批准号：
8582090
负责人：
Israel DAVID GOLDMAN
金额：
$ 6.51万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-06-01 至 2018-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8582090
关键词：
Accounting Albert Einstein Cancer Center Animal Experimentation Animal Housing Animal Husbandry Animal Technicians Animal Welfare Animals Biopsy Budgets Cancer Center Censuses Comprehensive Health Care Consultations Day Care Diagnostic Services Environment Faculty Funding Genotype Goals Growth Health Histopathology House mice Housing Human Resources IACUC Implant Individual Infectious Agent Institutes Instruction Laboratory Animals Malignant Neoplasms Measures Mission Monitor Morbidity - disease rate Mus NCI-Designated Cancer Center Pathologic Pathologist Pharmaceutical Preparations Phenotype Price Program Reviews Programmed Instruction Protocols documentation Quarantine Reporting Research Research Personnel Resource Sharing Resources Rodent Services Specific Pathogen Frees Technology Tissues Training Translational Research Veterinarians Wages animal care animal facility flexibility germ free condition high standard in vivo member mortality operation programs quality assurance research study tumor

项目摘要

The Animal Barrier Shared Resource (ABSR) provides specific pathogen-free (SPF) rodent housing and services that are critical to the research of Albert Einstein Cancer Center (AECC) members and the Center's programmatic activities. The ABSR is a component of the Institute of Animal Studies (IAS), Einstein's AAALAC accredited animal care & use program. The ABSR provides a broad spectrum of animal husbandry services including: veterinary care, comprehensive rodent quality assurance and quarantine programs. There is an intensive program of instruction for AECC members and their trainees prior to allowing their access to the facilities to implement matings, genotype progeny, characterize mouse phenotypes, implant tumors and measure their growth, administer drugs, and obtain tissue biopsies. The capacity of the ABSR has been substantially increased since 2007 with the creation of a new SPF barrier facility in the Price Center that was opened in 2008 with a housing capacity of approximately 8,000 cages. With renovation and expansion of the two other existing facilities there is now an overall SPF mouse housing capacity of 25,000 cages. AECC members accounted for 58% of the total ABSR usage (cage care-days) and 47% of the maximum housing capacity of the resource during the reporting year (FYE'12). AECC investigators also account for 51% of mouse purchases and 54% of miscellaneous services provided by the ABSR /IAS. The IAS has an operating budget of over $7 M. Personnel expenses account for about 64% of the operating budget. IAS personnel include three faculty Laboratory Animal Veterinarians (including the Director), an Operations Manager, three Facility Supervisors, five Veterinary Technicians, office staff, and approximately 48 Animal Caretakers. The support requested in this application provides partial salary support for the ABSR Director, Operations manager, and Animal Facility Supervisors in each of the three main ABSR Facilities, and constitutes about 5% of total IAS personnel expenses.

动物屏障共享资源 (ABSR) 提供特定的无病原体 (SPF) 啮齿动物住房和服务，这对于阿尔伯特·爱因斯坦癌症中心 (AECC) 成员的研究和该中心的计划活动至关重要。 ABSR 是动物研究所 (IAS) 的组成部分，IAS 是爱因斯坦的 AAALAC 认可的动物护理和使用计划。 ABSR 提供广泛的畜牧业服务，包括：兽医护理、全面的啮齿动物质量保证和检疫计划。在允许 AECC 成员及其受训人员使用设施进行交配、对后代进行基因分型、表征小鼠表型、植入肿瘤并测量其生长、施用药物和获取组织活检之前，有一个强化的指导计划。自 2007 年以来，ABSR 的容量已大幅增加，在价格中心建立了一个新的 SPF 屏障设施，该设施于 2008 年启用，可容纳约 8,000 个笼子。随着另外两个现有设施的改造和扩建，目前 SPF 小鼠笼舍容量已达 25,000 个笼子。在报告年度 (FYE'12) 中，AECC 成员占 ABSR 总使用量（笼养天数）的 58% 和资源最大住房容量的 47%。 AECC 调查员还负责 ABSR /IAS 鼠标采购的 51% 和提供的杂项服务的 54%。 IAS 的运营预算超过 700 万美元。人员费用约占运营预算的 64%。 IAS 人员包括三名实验动物兽医（包括主任）、一名运营经理、三名设施主管、五名兽医技术员、办公室工作人员和大约 48 名动物管理员。本申请中请求的支持为三个主要 ABSR 设施中每一个的 ABSR 总监、运营经理和动物设施主管提供部分工资支持，约占 IAS 人员总开支的 5%。