Systems Biology of Infectious Diseases: Pathogenesis to Personalized Medicine

传染病的系统生物学：个性化医疗的发病机制

• 批准号: 8789251
• 负责人: MICHAEL G KATZE
• 金额: $ 0.84万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8789251
• 关键词: Acquired Immunodeficiency Syndrome; Award; Bioinformatics; Caring; Collaborations; Committee Members; Communicable Diseases; Computational Biology; Development; Disease; Disease Outcome; Emerging Communicable Diseases; Environment; Family; Fostering; Funding; Future; Gender; Genetic; Genome; Goals; Individual; Infection; Infectious Diseases Research; Institutes; Investments; Learning; Mathematics; Medicine; Methods; Microbe; Minority; National Institute of Allergy and Infectious Disease; Oral; Participant; Pathogenesis; Patients; Postdoctoral Fellow; Process; Research; Research Personnel; Resources; Respiratory Tract Infections; Role; Science; Scientist; Services; System; Systems Biology; Technology; Travel; Tuberculosis; United States National Institutes of Health; Universities; Washington; abstracting; base; computer science; fighting; graduate student; interest; multidisciplinary; new technology; pandemic influenza; pathogen; posters; prevent; programs; public health relevance; response; symposium; systems research; technology development; web site

DESCRIPTION (provided by applicant): This conference will feature discussions on computational biology and bioinformatics, technology development, and the use of systems-level approaches in a wide range of infectious disease applications. We will highlight research aimed at understanding, treating, and preventing conditions such as AIDS, respiratory infections, and tuberculosis. We will also feature presentations on the identification of emerging pathogens, the role of host genetics in determining disease outcome, and the promises of personalized care. Our goal is to provide a unique opportunity for a multidisciplinary group of investigators to learn from each other, discuss how to exploit new resources and technologies, and decide where to focus future research and development efforts. The conference will also provide abundant opportunities for networking and for establishing new collaborations. To encourage interactions between attendees and with corporate sponsors, we will cap registration at 150 attendees. Attendance is open to all interested individuals, and registrations will be processed on a first-come basis. The conference will be held at the Orin Smith Conference Center located on the South Lake Union campus of the University of Washington. To encourage attendance by young scientists, we will make available a total of 10 travel awards to graduate students and postdoctoral fellows. Gender and minority representation, as well as scientific expertise and merit, have been considered during the process of choosing members of committees and speakers for the conference. Information regarding family care services will be posted on the conference website and will be included with the registration materials provided to attendees. The scientific program will consist of five oral sessions and a poster session. Oral sessions will include presentations by invited speakers and additional speakers chosen from submitted abstracts. At the end of selected sessions, there will be a round-table discussion to promote exchanges between presenters and conference participants and to focus on important or controversial issues that relate to themes in the respective session. Ongoing advances in genome science, technology, and computation create a rapidly changing research environment that makes this conference timely, significant, and exciting. Our goal is to facilitate the exchang of information in this rapidly growing field and to help define future directions for incorporating systems biology approaches into translational and infectious disease research.

描述（由申请人提供）：该会议将进行有关计算生物学和生物信息学，技术开发以及在广泛传染病应用中使用系统级方法的讨论。我们将重点介绍旨在理解，治疗和预防艾滋病，呼吸道感染和结核病等疾病的研究。我们还将展示有关鉴定新兴病原体的演讲，宿主遗传学在确定疾病结果中的作用以及个性化护理的承诺。我们的目标是为多学科的研究人员提供一个独特的机会，以互相学习，讨论如何利用新的资源和技术，并决定在哪里重点关注未来的研发工作。会议还将为网络和建立新的合作提供丰富的机会。为了鼓励与会者与公司赞助商之间的互动，我们将在150名与会者的情况下限定注册。出勤向所有感兴趣的人开放，并且将以先到先决的方式进行注册。会议将在华盛顿大学南湖联合校园的Orin Smith会议中心举行。为了鼓励年轻科学家参加，我们将为研究生和博士后研究员提供10个旅行奖。在为会议选择委员会成员和发言人的过程中，考虑了性别和少数群体代表以及科学专业知识和优点。有关家庭护理服务的信息将发布在会议网站上，并将包含在提供给与会者的注册材料中。科学计划将由五个口头会议和海报会议组成。口头会议将包括受邀发言人和从提交摘要中选择的其他演讲者的演讲。在选定的会议结束时，将进行圆桌会议讨论，以促进演讲者与会议参与者之间的交流，并专注于与主题相关的重要或有争议的问题。基因组科学，技术和计算的持续进展创造了一个快速变化的研究环境，使这次会议及时，重要和令人兴奋。我们的目标是在这个快速发展的领域中促进信息交流，并帮助定义未来的指示 系统生物学方法是转化和传染病研究。

项目成果

A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.

• DOI: 10.1128/mbio.00325-10
• 发表时间: 2011-03-01
• 期刊: mBio
• 影响因子: 6.4
• 作者: Aderem A;Adkins JN;Ansong C;Galagan J;Kaiser S;Korth MJ;Law GL;McDermott JG;Proll SC;Rosenberger C;Schoolnik G;Katze MG
• 通讯作者: Katze MG