Underwater Treadmill Training in Adults with Incomplete Spinal Cord Injury

不完全性脊髓损伤成人的水下跑步机训练

• 批准号: 8689494
• 负责人: DON W MORGAN
• 金额: $ 38.89万
• 依托单位: MIDDLE TENNESSEE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8689494
• 关键词: Address; Adult; Aerobic; Affect; Behavior; Body Weight; Cardiovascular system; Characteristics; Clinic; Clinical; Communities; Computers; Control Groups; Crossover Design; Environment; Equilibrium; Exercise; Fitness Centers; Gait; Goals; Health; Height; Home environment; Hospitals; Individual; Laboratory Research; Leg; Life; Measures; Monitor; Motor; Orthotic Devices; Participant; Performance; Persons; Physical Function; Physical activity; Physiological; Population; Randomized; Recovery; Regimen; Rehabilitation therapy; Research; Resistance; Retirement; Sleep; Speed; Spinal cord injury; Sports Medicine; Stress; System; Techniques; Technology; Temperature; Testing; Therapeutic; Time; Training; Training Programs; Trauma; Walking; Water; Woman; Work; base; community setting; conditioning; design; disability; experience; fitness; gait retraining; improved; improved mobility; land use; men; muscle strength; programs; public health relevance; response; robot assistance; sedentary; social; treadmill training

DESCRIPTION (provided by applicant): Without appropriate physical activity, mobility and fitness are diminished in persons with incomplete spinal cord injury (iSCI), leading to degenerative physiological changes that negatively affect health and physical function. Conventional rehabilitation programs are designed to facilitate independence in performing functional tasks such as walking, but loss of muscle strength, endurance, and motor coordination limit the capacity of individuals with SCI to participate in traditional overground ambulation training regimens. While the use of land-based, body weight-supported treadmill training and computer-driven gait orthoses has led to gains in walking ability following iSCI, notable limitations associated with both gait retraining techniques have provided a strong impetus to explore new, activity- based therapies to improve walking performance in this clinical population. Against this backdrop, our primary research goal is to quantify the functional benefits of underwater treadmill training in adults with iSCI. Specifically, we hypothesize that underwater treadmill training (UTT) will improve daily ambulatory activity and reduce sedentary time, increase participation in life activities, and improve endurance walking performance in adults with iSCI. To test these hypotheses, 30 men and women with iSCI will be assigned to either an UTT group (n = 15; Group 1) or a control group (n = 15; Group 2) using a randomized crossover design. Participants in Group 1 will complete 16 weeks of underwater treadmill walking (3x/week) featuring systematic and gradual increases in exercise intensity and duration followed by 16 weeks during which retention of gains made during UTT will be evaluated. Conversely, participants in Group 2 will initially maintain a normal living routine for 16 weeks and then engage in UTT for 16 weeks. Results from the proposed study will allow us to establish the rehabilitative potential of underwater treadmill training in adults with incomplete spinal cord injury and better understand the synergistic effects of conditioning adaptations on physical activity, social and interpersonal aspects of disability, and aerobic health in this clinial population. Our ultimate objective in this work is to extend the access of underwater treadmill training, a technologically- advanced therapeutic option, beyond the research laboratory and into a variety of clinical and public settings, such as hospitals, trauma rehabilitation facilities recreational fitness centers, and retirement communities, where small, portable water-based treadmills can be easily transferred into pools.

描述（由申请人提供）：如果不进行适当的体力活动，不完全脊髓损伤 (iSCI) 患者的活动能力和健康能力就会下降，导致退行性生理变化，对健康和身体功能产生负面影响。传统的康复计划旨在促进独立执行行走等功能性任务，但肌肉力量、耐力和运动协调性的丧失限制了 SCI 患者参与传统地面步行训练方案的能力。虽然使用基于地面的体重支撑跑步机训练和计算机驱动的步态矫形器可以提高 iSCI 后的步行能力，但与这两种步态再训练技术相关的显着局限性为探索基于活动的新方法提供了强大的动力。改善该临床人群步行能力的疗法。在此背景下，我们的主要研究目标是量化水下跑步机训练对 iSCI 成人的功能益处。具体来说，我们假设水下跑步机训练 (UTT) 将改善 iSCI 成人的日常行走活动并减少久坐时间，增加对生活活动的参与，并提高耐力步行表现。为了检验这些假设，使用随机交叉设计将 30 名患有 iSCI 的男性和女性分配到 UTT 组（n = 15；第 1 组）或对照组（n = 15；第 2 组）。第 1 组的参与者将完成 16 周的水下跑步机行走（3 次/周），其特点是系统地逐步增加运动强度和持续时间，然后在 16 周期间评估 UTT 期间所取得成果的保留情况。相反，第 2 组的参与者最初将保持正常的生活习惯 16 周，然后进行 16 周的 UTT。拟议研究的结果将使我们能够确定水下跑步机训练对不完全脊髓损伤成人的康复潜力，并更好地了解本临床中条件适应对身体活动、残疾的社会和人际方面以及有氧健康的协同作用人口。我们这项工作的最终目标是将水下跑步机训练这一技术先进的治疗选择扩展到研究实验室以外的各种临床和公共场所，例如医院、创伤康复设施、休闲健身中心和退休场所。社区中，小型便携式水基跑步机可以轻松转移到游泳池中。