Ambulatory assessment of alcohol use, mood dysregulation, and alcohol craving

酒精使用、情绪失调和酒精渴望的动态评估

• 批准号: 8734307
• 负责人: KENNETH JAMES SHER
• 金额: $ 17.41万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-15 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8734307
• 关键词: Affective; Alcohol abuse; Alcohol consumption; Alcohol dependence; Alcoholic Beverages; Algorithms; Anxiety Disorders; Area; Behavior; Borderline Personality Disorder; Cardiac; Clinic; Clinical; Clinical Skills; Clinical assessments; Collection; Computer software; Consult; Crime; Data; Development; Devices; Disease; Electronics; Emotional; Emotions; Environment; Equipment; Glosso-Sterandryl; Health; Healthcare; Heart Rate; Heavy Drinking; Hour; Individual; Interview; Interviewer; Laboratories; Learning; Life; Light; Machine Learning; Measures; Methodology; Methods; Modeling; Monitor; Mood Disorders; Moods; Network-based; Outpatients; Paper; Participant; Patient Self-Report; Patients; Phase; Physiologic Monitoring; Physiological; Productivity; Psychopathology; Psychophysiology; Public Health; Questionnaires; Reliance; Reporting; Research; Research Project Grants; Respiration; Sampling; Secure; Series; Societies; Statistical Models; Stimulus; Substance Use Disorder; Symptoms; System; Technology; Telephone; Time; Validity and Reliability; Video Recording; Wireless Technology; alcohol craving; alcohol use disorder; base; clinically significant; cost; craving; cue reactivity; data exchange; design; diaries; drinking; economic cost; experience; handheld mobile device; heart rate variability; high risk; improved; indexing; innovation; interdisciplinary collaboration; monitoring device; mortality; negative mood; positive mood; public health relevance; respiratory; response; sensor

DESCRIPTION (provided by applicant): Excessive alcohol use has many negative health consequences, including higher risk of mortality. In addition, in 2006, the estimated economic cost of excessive drinking was $223.5 billion when the combined costs of lost productivity, health and health care, and crime are considered61. Despite unparalleled advances in technology over the last several decades, the clinical assessment of features and correlates of alcohol use disorders (and psychopathology more generally), still primarily relies on traditional paper-and-pencil questionnaires and face-to- face clinical interviews. However, these tried-and-true methods are limited in a number of ways, including total reliance on patients' retrospective self-report, the skill of the clinical interviewer, and the artificial setting of the assessment (te clinic consulting room). The present study proposes to use an innovative methodology, ambulatory assessment (AA) to describe and investigate alcohol use and dependence-related symptomatology (specifically, cue- reactivity/craving), and emotional dysregulation among psychiatric outpatients with disorders characterized by clinical significant emotional dysregulation problems (mood disorders, anxiety disorders, or borderline personality disorder) while in their natural environment. This "real-world" approach can shed light on the causes and correlates of alcohol dependence, and suggest improvements in treatment approaches.

描述（由申请人提供）：过量的饮酒会带来许多负面的健康后果，包括更高的死亡风险。此外，在2006年，当考虑生产率损失，健康和医疗保健以及犯罪的总成本61时，过度饮酒的估计经济成本为2235亿美元。尽管在过去几十年中技术方面取得了无与伦比的进步，但对酒精使用障碍的特征和相关性（以及更广泛的心理病理学）的临床评估仍然主要依赖于传统的纸笔问卷和面对面的临床访谈。但是，这些久经考验的方法在多种方面受到限制，包括完全依赖患者回顾性自我报告，临床访问者的技能以及评估的人为设置（TE Clinic Consulting Room）。本研究建议使用创新的方法，卧床评估（AA）来描述和调查与依赖性和依赖相关的症状学（具体是提示反应/渴望/渴望），以及精神病患者之间的情绪失调，与临床上的情绪失调问题（情绪失调，焦虑症状，偏向于他们的临床性情绪障碍），在临床上具有严重的情绪障碍，或者是自然的偏向性，他们的情绪障碍，或者是他们的自然偏差。这种“现实世界”方法可以阐明酒精依赖的原因和相关性，并提出改善治疗方法。