Exploring affect-motivated alcohol use as a value-based decision-making process

探索情感驱动的饮酒作为基于价值的决策过程

• 批准号: 10738470
• 负责人: Jonas Dora
• 金额: $ 17.46万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-06 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10738470
• 关键词: Addictive Behavior; Affect; Affective; Alcohol abuse; Alcohol consumption; Alcoholic beverage heavy drinker; Alcohols; Award; Behavior; Behavioral Model; Binge Eating; Cognitive Science; Computer Models; Consumption; Data; Decision Making; Development; Diffusion; Doctor of Philosophy; Ecological momentary assessment; Educational workshop; Emotional; Emotions; Empirical Research; Environment; Food; Foundations; Future; Goals; Human; Individual; Institution; Intoxication; Laboratories; Learning; Life; Maps; Mentors; Meta-Analysis; Methods; Modeling; Moods; Motivation; National Institute on Alcohol Abuse and Alcoholism; Negative Reinforcements; Participant; Pathway interactions; Patient Self-Report; Persons; Phase; Positioning Attribute; Positive Reinforcements; Postdoctoral Fellow; Prevention; Process; Psychological reinforcement; Psychology; Regulation; Reporting; Research; Resources; Risk; Scientist; Smoking; Sum; Symptoms; Testing; Training; Translating; Universities; Washington; alcohol abuse therapy; alcohol reinforcement; alcohol research; alcohol use disorder; career; coping; drinking; drinking behavior; emotion regulation; emotional experience; experience; experimental study; improved; innovation; insight; laboratory experiment; negative affect; novel; positive emotional state; reinforcer; response; skills; sobriety; symposium; theories; Addictive Behavior; Affect; Affective; Alcohol abuse; Alcohol consumption; Alcoholic beverage heavy drinker; Alcohols; Award; Behavior; Behavioral Model; Binge Eating; Cognitive Science; Computer Models; Consumption; Data; Decision Making; Development; Diffusion; Doctor of Philosophy; Ecological momentary assessment; Educational workshop; Emotional; Emotions; Empirical Research; Environment; Food; Foundations; Future; Goals; Human; Individual; Institution; Intoxication; Laboratories; Learning; Life; Maps; Mentors; Meta-Analysis; Methods; Modeling; Moods; Motivation; National Institute on Alcohol Abuse and Alcoholism; Negative Reinforcements; Participant; Pathway interactions; Patient Self-Report; Persons; Phase; Positioning Attribute; Positive Reinforcements; Postdoctoral Fellow; Prevention; Process; Psychological reinforcement; Psychology; Regulation; Reporting; Research; Resources; Risk; Scientist; Smoking; Sum; Symptoms; Testing; Training; Translating; Universities; Washington; alcohol abuse therapy; alcohol reinforcement; alcohol research; alcohol use disorder; career; coping; drinking; drinking behavior; emotion regulation; emotional experience; experience; experimental study; improved; innovation; insight; laboratory experiment; negative affect; novel; positive emotional state; reinforcer; response; skills; sobriety; symposium; theories

PROJECT SUMMARY/ABSTRACT K99 training: The goal of the proposed K99/R00 Pathway to Independence Award is to provide Dr. Jonas Dora with training needed to launch his career as an independent scientist. Following his PhD in cognitive psychology, Dr. Dora has already started to make important contributions to the field of alcohol use research as a postdoctoral research fellow in the Department of Psychology at the University of Washington. The proposed K99 training period builds on Dr. Dora’s PhD background and his current training in the study of alcohol use in natural environments. The K99 phase will provide a period of intensive training in the combined study of alcohol use with experimental, ecological momentary assessment, and computational approaches, and will position Dr. Dora to make substantial contributions to the field of alcohol research over the course of his career. Dr. Dora will learn from the proposed mentor (Dr. Kevin King), local collaborators (Drs. William George, Mary Larimer) and external collaborators (Drs. Matt Field, James Murphy, Katie Witkiewitz), who are leading experts in the field of alcohol use research using both experimental and ecologically valid approaches, as well as the advanced computational modeling of behavioral and subjective data. In addition, Dr. Dora will attend courses, scientific conferences, and workshops to meet his training objectives. The University of Washington is a world-class research institution that provides an optimal environment, the necessary resources, and a stimulating intellectual space to facilitate successful completion of this project. K99 research: Together with his mentor and collaborators, Dr. Dora will conduct controlled experiments in a simulated bar environment as well as studies in people’s natural drinking environment to test the idea that negative and positive reinforcement of alcohol can be observed when heavy drinkers with and without symptoms of alcohol use disorder (AUD) make decisions between alcohol and substance-free reinforcers. R00 research: Dr. Dora will translate the K99 research using a task involving hypothetical choices between alcohol and substance-free reinforcers into an ecologically valid test of the hypothesis that positive and negative affect differentially motivate real-world value-based decisions to consume alcohol (vs regulate affect via alternative emotion regulation strategies) in heavy drinkers with/without symptoms of AUD in everyday life. Significance: By combining methods from cognitive psychology and alcohol use research, this research will provide a novel test of the idea that alcohol use is reinforcing in the face of positive and negative emotions, and in that way will advance NIAAA’s strategic aim to identify mechanisms that contribute to AUD. By studying alcohol use as a form of value-based decision-making, the insights from this project will suggest new possibilities to target people’s emotions in the prevention and treatment of alcohol use disorder.

项目摘要/摘要 K99培训：拟议的K99/R00独立奖的目标是为Jonas博士提供 多拉（Dora）接受培训需要启动他作为独立科学家的职业生涯。继他的认知博士学位 心理学，Dora博士已经开始为酒精使用研究领域做出重要贡献 作为华盛顿大学心理学系的博士后研究员。这 拟议的K99培训期建立在Dora博士的博士背景以及他目前在研究中的培训 自然环境中的饮酒。 K99阶段将在合并后提供深入的培训 研究饮酒，用于实验性，生态瞬时评估和计算方法的研究， 并将将多拉博士定位为在整个过程中为酒精研究领域做出重大贡献 他的职业生涯。 Dora博士将向拟议的导师（Kevin King博士）学习当地合作者（威廉博士） 乔治，玛丽·拉里默（Mary Larimer）和外部合作者（Matt Field博士，詹姆斯·墨菲（James Murphy），凯蒂·维特基维茨（Katie Witkiewitz）） 使用实验和生态有效的方法，在酒精使用研究领域的领先专家， 以及行为和主观数据的高级计算建模。此外，Dora博士将 参加课程，科学会议和讲习班，以实现他的培训目标。大学 华盛顿是一家世界一流的研究机构，提供最佳环境，必要的环境 资源和刺激的智力空间，以促进该项目成功完成。 K99研究：Dora博士将与他的导师和合作者一起进行对照实验 模拟酒吧环境以及人们在人们自然饮酒环境中的研究，以测试以下想法 当有和没有的重饮酒者和没有 酒精使用障碍（AUD）的症状在酒精和无物质增强剂之间做出决定。 R00研究：Dora博士将使用涉及假设选择的任务来翻译K99研究 酒精和无物质的增强剂对阳性和 负面影响不同的激励基于现实世界的基于价值的决策消耗酒精（vs调节影响 通过替代情绪调节策略）在日常生活中有/没有AUD症状的重饮者中。 意义：通过结合认知心理学和饮酒研究的方法，这项研究将 提供了一个新的考验，即面对积极和负面情绪，饮酒正在加强，并且 这样一来，NIAAA的战略目的是确定有助于AUD的机制。通过学习 酒精使用作为基于价值的决策形式，该项目的见解将暗示新的 针对人们在预防和治疗酒精使用障碍方面的情绪的可能性。