Research Training in Gene-Environment Interaction in China

中国基因与环境相互作用研究培训

基本信息

批准号：
8652330
负责人：
Dongfeng Gu
金额：
$ 22.11万
依托单位：
TULANE UNIVERSITY OF LOUISIANA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-07-16 至 2017-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8652330
关键词：
Academy Award Biometry Cardiovascular Diseases Cardiovascular system China Chinese People Chronic Chronic Disease Clinical Clinical Research Collaborations Communicable Diseases Congresses Disease Doctor&apos s Degree Environmental Exposure Epidemiologic Methods Epidemiologic Studies Epidemiologist Epidemiology Faculty Genetic Genetic Predisposition to Disease Genetic Variation Genomics Heart Hospitals Human Institutes Interdisciplinary Study International Joints Knowledge Laboratory Research Leadership Longevity Medical Mentorship Molecular Genetics NIH Program Announcements Play Population Research Public Health Schools Recruitment Activity Research Research Methodology Research Personnel Research Training Role Science Trainers Training Training Training Programs Tropical Medicine Universities Work design experience gene environment interaction genetic epidemiology graduate student medical schools multidisciplinary programs response skills statistics

项目摘要

DESCRIPTION (provided by applicant): This is a joint application of the Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA, the Cardiovascular Institute and Fu Wai Hospital of the Chinese Academy of Medical Sciences and Peking Union Medical College, and the National Center for Cardiovascular Diseases of China to provide research training in gene-environment interaction in chronic diseases across the lifespan in China in response to Program Announcement: Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43). Most chronic, non-communicable diseases and disorders are likely determined by genetic predisposition, environmental exposure and their interactions. This multidisciplinary training program is built on the long- standing collaboration in chronic disease research between the US and Chinese participating institutes and aims to strengthen capacity for gene-environment interaction research in chronic diseases in China. The specific aims are: (1) to establish a unique, interdisciplinary program for graduate students pursuing doctoral degrees at the Peking Union Medical College (PUMC), with a strong emphasis on multidisciplinary research training designed to study genetic variation, environmental exposure, and their interactions in chronic diseases in China. After the first year of course work at PUMC in China, the trainees will take advanced courses in genetics, statistics, epidemiology and clinical research methods, as well as gain experience in population or laboratory research, during their second year at Tulane University in the US. The trainees will conduct their dissertation research in China under co-mentorship from faculty at PUMC and Tulane. They will receive their doctoral degrees from PUMC; (2) To provide multidisciplinary postdoctoral research training in gene- environment interaction for junior researchers and clinicians in order to expand their research directions in chronic diseases. We will recruit geneticists and train them with the knowledge and skills for epidemiologic and clinical research and recruit epidemiologists and clinical researchers and train them with the knowledge and skills for genomic research at Tulane University for 6 months; (3) to initiate a Summer Institute in Gene- Environment Interaction in China and offer short courses in Biostatistics, Epidemiological Methods, Clinical Research Methods, Human Molecular Genetics, Statistical Genetics, Genetic Epidemiology, and Chronic Disease Epidemiology. We will widely publicize this summer institute and make the course materials available online to a wide audience in China; and 4) To organize a special session in Gene-Environment Interaction at the China Heart Congress to promote research in gene-environment interaction. This program takes the "train the trainer" approach, and graduates from this program will play a leadership role in building research and training capacity in gene-environment interaction in chronic diseases in China.

描述（申请人提供）：这是美国路易斯安那州新奥尔良杜兰大学公共卫生与热带医学院、中国医学科学院心血管研究所、北京协和医学院联合申请和国家心血管病中心将在中国提供有关慢性病基因与环境相互作用的研究培训，以响应整个生命周期慢性非传染性疾病和紊乱的计划公告寿命：福格蒂国际研究培训奖（NCD-LIFESPAN）（D43）。大多数慢性非传染性疾病和失调可能是由遗传倾向、环境暴露及其相互作用决定的。该多学科培训项目建立在美国和中国参与机构之间在慢性病研究方面的长期合作基础上，旨在加强中国慢性病基因与环境相互作用研究的能力。具体目标是：（1）为北京协和医科大学攻读博士学位的研究生建立一个独特的跨学科项目，重点强调旨在研究遗传变异、环境暴露及其影响的多学科研究培训。中国慢性病的相互作用。在中国协和医学院完成第一年的课程学习后，学员将在美国杜兰大学的第二年学习遗传学、统计学、流行病学和临床研究方法的高级课程，并获得人口或实验室研究的经验。学员将在北京协和大学和杜兰大学教师的共同指导下在中国进行论文研究。他们将在北京协和医学院获得博士学位；（2）为初级研究人员和临床医生提供基因-环境相互作用方面的多学科博士后研究培训，以拓展他们在慢性病方面的研究方向。我们将招募遗传学家并培训他们流行病学和临床研究的知识和技能，并招募流行病学家和临床研究人员并在杜兰大学培训他们进行基因组研究的知识和技能，为期6个月；（3）在中国开办基因-环境相互作用暑期学院，开设生物统计学、流行病学方法、临床研究方法、人类分子遗传学、统计遗传学、遗传流行病学、慢性病流行病学等短期课程。我们将广泛宣传本次暑期学院，并将课程材料在线提供给中国广大受众； 4）在中国心脏大会上举办基因与环境相互作用专题会议，推动基因与环境相互作用研究。该项目采取“培养培训师”的方式，该项目的毕业生将在中国慢性病基因与环境相互作用的研究和培训能力建设中发挥领导作用。