Developmental Research Core

发展研究核心

基本信息

批准号：
8715341
负责人：
Meir Stampfer
金额：
$ 15.51万
依托单位：
HARVARD SCHOOL OF PUBLIC HEALTH
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-06-01 至 2016-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8715341
关键词：
Area Award Basic Science Cancer Center Clinical Medicine Commit Complement Data Collection Data Set Development Ensure Epidemiology Fostering Funding Goals Grant Grant Review Institution Leadership Letters Malignant Neoplasms Malignant neoplasm of prostate Measures Mentorship Methods Mission Obesity Obesity associated cancer Peer Review Phenotype Pilot Projects Principal Investigator Process Public Health Schools Research Research Activity Research Personnel Research Project Grants Research Support Resources Review Committee Statistical Methods T-Cell Receptor-Rearrangement Excision DNA Circles Training Training Activity United States National Institutes of Health Work anticancer research base career career development data sharing energy balance expectation experience high risk improved innovation novel strategies programs sound

项目摘要

Developmental Core Core Director: Meir Stampfer, MD, DrPH Summary: The mission of the Developmental Core is to foster the development of energetics and cancer research by supporting investigator-initiated, smaller-scale, highly innovative (and high-risk) research projects within the Harvard TREC Center and across TREC Centers. Successful projects will provide the basis for larger-scale research that is closely integrated with the TREC, but with independent funding. This mechanism will maximize and leverage the TREC resources to foster pioneering transdisciplinary research in this broad area. It will emphasize the support of new investigators starting a career in obesity and cancer-related research. It also supports experienced investigators who aim to use novel approaches to study energy balance and cancer that complement the scope of existing Center activities. We will make special effort to identify and support work in areas viewed as transdisciplinary and synergistic across different fields and institutions. The Han/ard School of Public Health has committed to provide matching funds ($150,000) to support additional pilot studies through the TREC mechanism (one within-TREC pilot project and two cross-TREC pilot projects). The goals ofthe Developmental Core are to support innovative and transdisciplinary research in energetics and cancer and to stimulate career development in energetics and cancer, with a particular emphasis on supporting new investigators. We have established a rigorous peer review process that includes initial submission and review of Letters of Intent and extensive review of full proposals by the Center Scientific Review Committee. The Core Director, Dr. Meir Stampfer, has a strong track record of continuous NIH-funded research in cancer over the past two decades, is principal investigator of two NIH training grants in cancer and is co-Director of the Dana-Farber/Harvard Cancer Center SPORE in prostate cancer. He has vast experience in serving (usually as Chair) on NIH grant review committees. He will oversee the management of this program, including solicitation and review of the pilot award applications, and mentorship and integration of the awardees into Center activities. The Core will foster smaller-scale innovative research that builds on the Center's theme and resources. The expectation is that the work of the Core will have an impact on the field that goes beyond our TREC activities.

发展核心核心主任：Meir Stampfer，医学博士、公共卫生博士摘要：发展核心的使命是促进能量学和癌症的发展通过支持研究者发起的、规模较小、高度创新（和高风险）的研究项目来进行研究哈佛 TREC 中心内和跨 TREC 中心。成功的项目将为与 TREC 紧密结合但有独立资助的更大规模研究。这个机制将最大限度地利用 TREC 资源，促进这一广泛领域的开创性跨学科研究区域。它将强调对开始肥胖和癌症相关职业的新研究人员的支持研究。它还支持经验丰富的研究人员致力于使用新方法来研究能量平衡和癌症，以补充现有中心活动的范围。我们将特别努力识别和支持被视为跨学科和跨不同领域和机构的协同领域的工作。这汉/阿德公共卫生学院已承诺提供配套资金（150,000 美元）以支持更多通过 TREC 机制开展试点研究（一项 TREC 内部试点项目和两项跨 TREC 试点项目）。发展核心的目标是支持能源学的创新和跨学科研究和癌症，并刺激能源学和癌症领域的职业发展，特别强调支持新的调查人员。我们建立了严格的同行评审流程，包括初步评审科学中心提交和审查意向书以及对完整提案进行广泛审查审查委员会。核心主任 Meir Stampfer 博士拥有 NIH 持续资助的良好记录过去二十年来对癌症的研究，是两项 NIH 癌症和癌症培训资助项目的首席研究员是丹娜—法伯癌症研究所/哈佛大学癌症中心 SPORE 前列腺癌联合主任。他拥有丰富的经验在 NIH 拨款审查委员会任职（通常担任主席）。他将监督该项目的管理计划，包括征集和审查试点奖项申请，以及指导和整合获奖者参加中心活动。该核心将促进小规模的创新研究，这些研究建立在中心的主题和资源。期望核心的工作能够对该领域产生影响这超出了我们的 TREC 活动范围。