ALCOHOL EFFECTS ON THE ADOLESCENT BRAIN

酒精对青少年大脑的影响

• 批准号: 8362834
• 负责人: STEPHEN MATTHEW MALONE
• 金额: $ 0.38万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362834
• 关键词: Adolescent; Alcohol consumption; Area; Brain; Drug usage; Functional Imaging; Funding; Grant; Image; Magnetic Resonance Imaging; Monozygotic Twinning; Monozygotic twins; NMR Spectroscopy; National Center for Research Resources; Performance; Principal Investigator; Psychophysiology; Research; Research Infrastructure; Resolution; Resources; Rewards; Source; Structure; United States National Institutes of Health; alcohol effect; cost; design; neuropsychological; relating to nervous system

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. he purpose of the project, which is ongoing, is to study 48 pairs of monozygotic twins using a longitudinal cotwin-control design to assess effects of alcohol and drug use on brain structure and function. The project uses a comprehensive and complementary battery of neuropsychological, psychophysiological and MRI assessment. MRI imaging includes high-resolution structural imaging for morphometric analyses and whole-brain functional imaging during performance of a task shown to be sensitive to reward-sensitive neural areas.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 该项目正在进行中，其目的是使用纵向 cotwin 对照设计来研究 48 对同卵双胞胎，以评估酒精和药物使用对大脑结构和功能的影响。该项目使用神经心理学、心理生理学和 MRI 评估的全面且互补的组合。 MRI 成像包括用于形态测量分析的高分辨率结构成像和执行对奖赏敏感神经区域敏感的任务期间的全脑功能成像。