Dynamics of Spoken Word Comprehension in Aphasia

失语症口语理解的动态

• 批准号: 8663589
• 负责人: Daniel Mirman
• 金额: $ 13.23万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8663589
• 关键词: Accounting; Adult; Affect; Aphasia; Behavioral; Case Series; Cognitive; Communication impairment; Comprehension; Computer Simulation; Concept Formation; Development; Distant; Eye; Faculty; Human Activities; Impairment; Individual; Investigation; Language; Lead; Learning; Measures; Mental Health; Methods; Modality; Modeling; Nature; Outcome; Participant; Patients; Pattern; Population; Process; Recording of previous events; Semantics; Social isolation; Speech; Speech Perception; Stroke; Structure; System; Techniques; Testing; Time; United States; Visual; Word Processing; Work; abstracting; aphasic; base; cognitive control; design; disability; functional disability; innovation; insight; language comprehension; language processing; lexical; lexical processing; meetings; novel; phonology; physical conditioning; rehabilitation strategy; research study; speech processing; success; theories

Project Summary/Abstract Aphasia is a stroke-related disability of language processing that affects about one million people in the United States. Human activity is so dependent on spoken communication that impairments of spoken language processing, such as aphasia, can be devastating. In addition to functional impairments such as inability to work, language impairments can also cause social isolation and its consequent negative outcomes on mental and physical health. Because language processing calls on many different cognitive faculties, aphasia may have many different underlying causes and each aphasic individual may have a subtly different impairment. Designing effective rehabilitation strategies depends on our understanding of the nature of the impairment, thus, the focus of this proposal is on using behavioral experiments and computational modeling methods to develop a formal theory of aphasic spoken word comprehension. The proposed experiments will investigate phonological, semantic, and cognitive control aspects of word processing in a large and diverse set of aphasic individuals and unimpaired control participants using behavioral and eye tracking measures. These measures will provide new insights into the dynamics of word processing in aphasia. Computational modeling will be used to develop and test formal accounts of word processing deficits in aphasia. With a better understanding of the underlying causes of aphasic language impairments and a formal model of aphasia, more effective rehabilitation strategies can be developed.

项目摘要/摘要 失语症是一种与中风相关的语言处理残疾，影响了约100万 美国的人。人类活动非常依赖口语交流，以至于 口语处理（例如失语症）的障碍可能是毁灭性的。此外 对于无法工作的功能障碍，语言障碍也可能导致社会 隔离及其在心理和身体健康方面的负面结果。因为 语言处理在许多不同的认知能力上，失语症可能有很多 不同的基本原因和每个失语症的人可能具有微妙的障碍。 设计有效的康复策略取决于我们对 因此，损害的重点是使用行为实验和 计算建模方法开发一种正式的口语口语理论 理解。提出的实验将研究语音，语义和 在大量的失语心集中，文字处理的认知控制方面 并使用行为和眼动措施损坏的控制参与者受损。这些 措施将为失语症中的文字处理动态提供新的见解。 计算建模将用于开发和测试文字处理的正式帐户 失语症的缺陷。更好地理解失语语言的根本原因 障碍和一种正式的失语症模型，更有效的康复策略可以是 发达。