Binaural Unmasking in Children with Cochlear Implants

人工耳蜗植入儿童的双耳揭秘

• 批准号: 8665807
• 负责人: Ann E Todd
• 金额: $ 2.03万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2015-01-08
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8665807
• 关键词: Acoustic Nerve; Acoustics; Address; Adult; Auditory; Auditory system; Bilateral; Bypass; Child; Clinical; Cochlea; Cochlear Implants; Cochlear implant procedure; Complex; Cues; Detection; Development; Ear; Electric Stimulation; Electrodes; Fostering; Frequencies; Goals; Hearing; Hearing Impaired Persons; Human Development; Individual; Knowledge; Lead; Learning; Left; Maintenance; Masks; Measures; Methods; Nerve Fibers; Neural Pathways; Noise; Performance; Peripheral; Predisposition; Process; Recording of previous events; Recovery; Relative (related person); Research; Signal Transduction; Source; Speech; Stimulus; System; Technology; Training Programs; Work; auditory deprivation; auditory stimulus; binaural hearing; design; experience; implantable device; improved; interest; public health relevance; relating to nervous system; sound; speech processing

DESCRIPTION (provided by applicant): Bilateral cochlear implantation in children is becoming increasingly popular in an effort to improve the ability to localize sound sources and understand speech in the presence of interfering stimuli. However, compared to the performance of normally hearing listeners, the binaural advantages that listeners with bilateral cochlear implants receive are limited. Sources of limitations in binaural hearing are currently poorly understood but may include limitations with cochlear implant devices and limitations in auditory system processing of listeners. Stimulation through bilateral cochlear implants provides degraded binaural information relative to the original acoustic signal and may fail to foster binaural hearig in children. Improving knowledge on the sensitivity of children with cochlear implants to binaural cues is necessary for improving technology and treatment of children with cochlear implants. Binaural masking level differences of children with bilateral cochlear implants will be examined using direct electrical stimulation to bypass the clinical cochlear implants and present bilaterall coordinated stimuli. Binaural sensitivity of children with bilateral cochlear implants will be examined relative to adults with bilateral cochlear implants and children with normal hearing. In addition, binaural sensitivity of children with normal hearing will be examined relative to adults with normal hearing. Binaural masking level differences are a measure of the binaural advantage for signal detection in noise. Examination of binaural masking level differences is important as it will improve understanding of limitations in the binaural advantage for segregating speech from noise. This study will further the understanding of binaural sensitivity of children with bilateral cochlear implants by examining binaural masking level differences under stimulus conditions which are relevant to real-world auditory stimuli. Aim 1 will examine the effect of stimulus bandwidth on binaural masking level differences using a single pair of left-right electrodes. Aim 2 will examine the effect of distance between electrodes using two pairs of left-right electrodes. Findings from this study will be informative for advancing cochlear implant technology in ways such that children receive benefits and will improve understanding of the development of the auditory system.

描述（由申请人提供）：儿童的双边人工耳蜗植入越来越流行，以提高在干扰刺激的情况下定位声音来源并理解语音的能力。但是，与正常听听的听众的表现相比，双边耳蜗植入物的双耳优势 接收有限。双耳听证中限制的来源目前了解不足，但 可能包括使用人工耳蜗设备的局限性以及听众系统处理中的局限性。通过双边人工耳蜗刺激提供相对于原始声学信号的双耳信息降解，并且可能无法促进儿童的双耳赫利格。改善人工耳蜗对双耳线索的敏感性的知识对于改善技术植入物儿童的技术和治疗是必要的。将使用直接电刺激检查双侧耳蜗植入物儿童的双耳掩蔽水平差异，以绕过临床耳蜗植入物并呈现双层配位刺激。相对于患有双侧人工耳蜗的成年人，将检查具有双侧人工耳蜗儿童的双耳敏感性和正常听力的儿童。此外，相对于听力正常的成年人，将检查具有正常听力的儿童的双耳敏感性。双耳掩蔽水平差异是对噪声中信号检测的双耳优势的度量。对双耳掩蔽水平差异的检查非常重要，因为它将改善对双耳优势的局限性的理解，从而将语音从噪声中隔离。这项研究将进一步理解双耳植入物儿童的双耳敏感性，通过检查与现实世界听觉刺激有关的刺激条件下的双耳掩蔽水平差异。 AIM 1将使用一对左右电极检查刺激带宽对双耳遮罩水平差异的影响。 AIM 2将使用两对左右电极检查电极之间距离的影响。这项研究的发现将提供信息，以推进人工耳蜗技术，以使儿童获得收益并提高对听觉系统发展的理解。