CLABSIs in Ambulatory Pediatric Oncology Patients

门诊儿科肿瘤患者中的 CLABSI

• 批准号: 8447347
• 负责人: Michael L Rinke
• 金额: $ 14.38万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8447347
• 关键词: CLABSIs; Ambulatory; Pediatric; Oncology; Patients

PROJECT SUMMARY The overall goal of this K08 mentored clinical scientist research career development award is to develop Dr. Michael Rinke into an independent clinical investigator in pediatric patient safety and quality, focusing on eliminating ambulatory central line-associated blood stream infections (CLABSIs). This goal will be accomplished during the grant period through doctorate level coursework in survey and cohort designs at the Johns Hopkins Bloomberg School of Public Health, advanced training in patient safety methodologies at Johns Hopkins' Center for Innovation in Quality Patient Care and at the Institute for Health Care Delivery and Research at Intermountain Healthcare, intensive mentorship from experienced health services researchers such as Dr. Marlene Miller, Dr. Allen Chen, Dr. Aaron Milstone and Dr. David Bundy and protected research time focused on CLABSIs in ambulatory pediatric oncology patients. Dr. Rinke's patient safety research aims to understand the epidemiology of ambulatory pediatric oncology patient CLABSIs and evaluate strategies to decrease ambulatory CLABSIs using best-practice care bundles. CLABSIs cause significant morbidity and mortality in all patients and are understudied in ambulatory populations. Dr. Rinke's research will 1) compare the burden of ambulatory pediatric oncology patient CLABSIs to inpatient pediatric oncology patient CLABSIs via CLABSIs counts, and describe specific risk factors and outcomes associated with ambulatory CLABSIs. The proposal will also 2) compare both pediatric homecare agency central line care policies and ambulatory pediatric oncology family central line care practices with best-practice central line care bundles, and describe barriers to implementation of best-practice central line care bundles in these populations. Finally, this proposal will 3) determine whether consistent clinic, homecare agency and family implementation of best-practice central line care bundles is associated with a decrease in ambulatory pediatric oncology patient CLABSI rates. Evaluating strategies to prevent CLABSIs in ambulatory pediatric oncology patients will improve outcomes for this vulnerable population. Successful completion of these projects will allow Dr. Rinke to become an independent clinical investigator and spread ambulatory CLABSI prevention efforts to other institutions and to other ambulatory pediatric and adult populations with long-term central lines. .

项目摘要 这个K08指导的临床科学家研究职业发展奖的总体目标是发展博士。 迈克尔·林克（Michael Rinke）成为儿科患者安全和质量的独立临床研究者 消除了与中央线相关的血流感染（Clabsis）。这个目标将是 通过调查和队列设计的博士学位课程在赠款期间完成 约翰·霍普金斯彭博公共卫生学院，患者安全方法的高级培训 约翰·霍普金斯（Johns Hopkins）优质患者护理创新中心和医疗保健研究所 以及Intermountain Healthcare的研究，经验丰富的医疗服务的密集指导 玛琳·米勒（Marlene Miller 受保护的研究时间集中在卧床儿科肿瘤患者中。林克博士的病人 安全研究旨在了解卧床儿科肿瘤学患者clabsis的流行病学 并评估使用最佳实践护理束减少门诊障碍的策略。 clabsis原因 所有患者的发病率和死亡率很高，在卧床人群中被研究了。博士 林克的研究将1）比较卧床儿科肿瘤患者的负担与住院 小儿肿瘤学患者通过clabsis计数，并描述特定的风险因素和结果 与卧床clabsis相关。该提案还将2）比较两个儿科家庭护理机构 中央线护理政策和门诊小儿肿瘤科最佳实践的中央线护理实践 中央线护理捆绑包，并描述实施最佳实践中央线护理捆绑包的障碍 这些人群。最后，该建议将3）确定一致的诊所，家庭保健机构和 最佳实践中央线护理束的家庭实施与卧床的减少有关 小儿肿瘤患者clabsi率。评估防止卧床儿科中的策略 肿瘤学患者将改善这一脆弱人群的预后。这些项目成功完成 将允许Rinke博士成为独立的临床研究者，并散布卧床CLABSI预防 向其他机构以及其他具有长期中心线的门诊小儿和成人人口的努力。 。