Stroke Trials Network-Regional Coordinating Center University of Pittsburgh (STN-UP)

中风试验网络-匹兹堡大学区域协调中心 (STN-UP)

• 批准号: 10847050
• 负责人: MARCELO ROCHA
• 金额: $ 7.95万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10847050
• 关键词: Acute; Admission activity; Adopted; Adult; Advisory Committees; Ambulatory Care Facilities; Area; Award; Catchment Area; Childhood; Childhood stroke; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Community Hospitals; Consultations; Data Coordinating Center; Discipline; Education; Emergency Care; Enrollment; Ensure; Equity; Ethnic Population; Faculty; Fostering; Funding; Geographic Locations; Health; Healthcare; Hospitals; Industry; Infrastructure; Institution; Leadership; Measures; Medical center; Minority; Minority Groups; Minority Health Research; Minority Recruitment; Neurosciences; Participant; Patient Recruitments; Patients; Pediatric Hospitals; Pennsylvania; Performance; Physicians; Population; Prevention; Randomized; Recovery; Rehabilitation therapy; Research; Research Personnel; Resources; Rotation; Rural; Satellite Centers; Saturn; Site; Stroke; Stroke prevention; StrokeNet trials; Structure; Supervision; Support Groups; Telemedicine; Time; Training; Translational Research; United States National Institutes of Health; Universities; Update; Woman; career; career development; cerebrovascular; collaborative approach; experience; improved; innovation; insight; meetings; outreach; participant enrollment; participant retention; performance site; programs; racial population; recruit; retention rate; rural area; skills; stroke trials; suburb; success; trial planning; trustworthiness; underserved area; working group; Acute; Admission activity; Adopted; Adult; Advisory Committees; Ambulatory Care Facilities; Area; Award; Catchment Area; Childhood; Childhood stroke; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Community Hospitals; Consultations; Data Coordinating Center; Discipline; Education; Emergency Care; Enrollment; Ensure; Equity; Ethnic Population; Faculty; Fostering; Funding; Geographic Locations; Health; Healthcare; Hospitals; Industry; Infrastructure; Institution; Leadership; Measures; Medical center; Minority; Minority Groups; Minority Health Research; Minority Recruitment; Neurosciences; Participant; Patient Recruitments; Patients; Pediatric Hospitals; Pennsylvania; Performance; Physicians; Population; Prevention; Randomized; Recovery; Rehabilitation therapy; Research; Research Personnel; Resources; Rotation; Rural; Satellite Centers; Saturn; Site; Stroke; Stroke prevention; StrokeNet trials; Structure; Supervision; Support Groups; Telemedicine; Time; Training; Translational Research; United States National Institutes of Health; Universities; Update; Woman; career; career development; cerebrovascular; collaborative approach; experience; improved; innovation; insight; meetings; outreach; participant enrollment; participant retention; performance site; programs; racial population; recruit; retention rate; rural area; skills; stroke trials; suburb; success; trial planning; trustworthiness; underserved area; working group

Abstract Bridge funding is being requested to support our NIH StrokeNet Regional Coordinating Center (RCC) at the University of Pittsburgh (STN-UP) during the gap in funding that would otherwise occur between the current award (U24NS107216) ending on 7/31/2023 and the proposed new RCC award (RFA-NS-23-010) starting on 12/1/2023. Continued NIH support during this time will be essential for the STN-UP RCC to continue delivering regulatory efficiency, academic expertise, and oversight of high-quality performance in StrokeNet trials of stroke prevention, treatment, and recovery across our regional network. The leadership, supervision, management, and direct support provided by the RCC PI, Marcelo Rocha, Co-Is, Clif Callaway and Dana Cummings and RCC Manager, Jason Weimer is key to continued participation and enrollment into the ASPIRE, CAPTIVA, MOST, SATURN, SleepSMART, TRANSPORT2 and VERIFY trials. Core leadership will be instrumental to the timely start-up and multi-site initiation for the upcoming RHSPSODY-2, FOCAS and SISTER trials across research network partner sites, which will be occurring during the time of the potential gap in funding. FOCAS is the first NIH pediatric stroke trial that the STN-UP RCC will be participating in at the UPMC Children’s Hospital of Pittsburgh. Our RCC PI and Research Manager meet monthly with our regional satellite sites to help optimize trial start-up and efficient enrollment across the network. STN-UP will continue to build on its successful infrastructure and experience from previous funding cycles to support regulatory efficiency, academic expertise, and high-quality performance in StrokeNet trials focused on stroke prevention, treatment, and recovery. Our large STN-UP research network includes University of Pittsburgh Medical Center (UPMC) and St. Luke’s University Health hospitals, covering large urban, suburban, and rural areas of Pennsylvania, to support trial recruitment of stroke participants with diverse backgrounds. The specific aims of the STN-UP RCC during the the gap between awards is to: 1. To continue our collaborative and administrative structure to rapidly implement StrokeNet trials and enroll patients across a wide range of adult and pediatric populations. 2. Foster participation of physicians, patients, and patient support groups with equitable representation of women and minorities to meet or exceed accrual requirements.

抽象的 正在要求桥梁资金支持我们的NIH Strokenet地区协调中心（RCC） 匹兹堡大学（STN-UP）在资金的差距中，否则会发生在当前 奖项（U24NS107216）以7/31/2023和拟议的新RCC奖（RFA-NS-23-010）结束。 12/1/2023。在此期间，NIH的持续支持对于Stn-Up RCC继续交付至关重要 中风试验中的高质量绩效的监管效率，学术专业知识和监督 我们区域网络的预防，治疗和恢复。领导，监督，管理和 RCC PI，Marcelo Rocha，Co-IS，Clif Callaway和Dana Cummings和RCC提供的直接支持 杰森·韦默（Jason Weimer）经理是继续参与和入学的关键 土星，睡觉，运输2和验证试验。核心领导将有助于及时 跨研究的启动和多站点启动 网络合作伙伴网站将在潜在的资金差距期间发生。 FOCAS是第一个 NIH儿科中风试验，即Stn-Up RCC将参加UPMC儿童医院 匹兹堡。我们的RCC PI和研究经理每月与我们的区域卫星站点开会，以帮助优化 试用启动和整个网络的有效注册。 Stn-Up将继续建立在成功的基础上 基础设施和以前的资金周期的经验，以支持监管效率，学术专业知识， 在跨语试验中的高质量性能集中在预防中风，治疗和恢复方面。我们的 大型Stn-UP研究网络包括匹兹堡大学医学中心（UPMC）和圣卢克大学 大学卫生医院，涵盖宾夕法尼亚州大型城市，郊区和粗糙地区，以支持试验 招募具有潜水员背景的中风参与者。 Stn-Up RCC的具体目的 奖项之间的差距是：1。继续我们的协作和行政结构以快速实施 在各种成人和小儿种群中进行的跨语试验和招募患者。 2。寄养参与 具有公平代表妇女和少数族裔的医师，患者和患者支持小组 满足或超过准确性要求。