NANOTOX 2014, 7th International Nanotoxicology Congress

NANOTOX 2014，第七届国际纳米毒理学大会

• 批准号: 8718354
• 负责人: Valerian E Kagan
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-17 至 2015-04-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8718354
• 关键词: Address; Adverse effects; Area; Biological; Biology; Cell physiology; Cells; Characteristics; Chemicals; Chemistry; Communities; Computer Simulation; Congresses; Cosmetics; Data; Dimensions; Discipline; Dose; Drug Kinetics; Ecosystem; Engineering; Environment; Environmental Health; Event; Exposure to; Fostering; Goals; Gray unit of radiation dose; Growth; Health; Human; Immune response; Industry; International; Knowledge; Laboratories; Life; Manufacturer Name; Meleagris gallopavo; Methodology; Methods; Modeling; Molecular; Molecular Machines; Molecular Mechanisms of Action; Nanotechnology; Occupational; Paper; Participant; Production; PubMed; Public Health; Publications; Publishing; Regulation; Research; Research Personnel; Risk; Risk Assessment; Safety; Scientist; Semiconductors; Series; Societies; Surface; Systems Biology; Technology; Tissues; Toxic effect; Toxicology; Work; base; design; experience; innovation; lectures; man; meetings; nano; nanomaterials; nanomedicine; nanoparticle; nanotoxicology; programs; public health relevance; response; scientific organization; symposium

DESCRIPTION (provided by applicant): Recent advances in nanotechnology have revolutionized all aspects of life, from engineering, semiconductors, building materials to cosmetics and nanomedicine. The unique physico-chemical characteristics combined with the vast surface area make the biological effects of nano-materials and their interactions with cells, tissues and biofluids largely unpredictable. The increasing use of engineered nanomaterials raises concerns about inadvertent exposure to these materials and the potential for adverse effects on human health and the environment. As a result of this, a new and explosively developing field of toxicology - nanotoxicology - has emerged. Experimental work in the field of nanotoxicology is progressing at exponential rate. In spite of this, there is still a fundamental lack of data on the potential impacts of nanomaterials n human health, and the environment, including natural ecosystems. Filling this gap of knowledge will require an unprecedented degree of national and international coordination between scientific organizations, regulatory agencies, and stakeholders. The proposed International Conference Nanotoxicology-2014 is an important step in this direction. The International Conference Nanotoxicology-2014 - to be held in Antalya, Turkey from April 23 through 26, 2014 - will bring together current research leaders in the field of toxicology of nanomaterial's from material scientists, chemists and manufacturers to molecular toxicologists, risk assessment experts as well as clinicians and translational scientists involved in biomedical applications of nanoparticles. Since 2006, when the first International conference on nanotoxicology has been initiated and organized in the US (Miami), a series of bi-annual meetings was conducted in Zurich (2008), Edinburgh (2010), and Beijing (2012). These conferences represented the major scientific events in the field of Nano toxicology whereby most innovative and significant breakthrough results in the emerging discipline were strategically disseminated and made available for the research community of scientists, representatives of nanomaterial's manufacturing industries, public health officials and experts in risk assessment/regulatory issues. The primary goal of the conference is to create the opportunity for cross disciplinary discussions for investigators with different fields of expertise working together to understand the chemistry, biology, molecular mechanisms of action and toxicity of nanomaterial's, hence to provide basis for risk assessments thus facilitating the design and production of nanomaterial's with minimized adverse effects on human health and the environment. The topics of the conference are focused on the latest most innovative areas of the exploding discipline of nanotoxicology: nanotoxicology and human toxicology, nano-environmental health and safety, eco-nanotoxicology, dose-response paradigm, molecular mechanisms of nontoxicity, immune responses to nanoparticles, nanomedicine, pharmacokinetics and particokinetics, nano-bio interface and nanobiomaterials, exposure scenarios and risk assessment of nanomaterials, systems biology approaches to nanosafety, In Silico modeling approaches including nano-QSARs, regulatory challenges of nanotechnology risks. A series of lectures on "Methods in nanosafety research" for young investigators will also be included in the program of the conference. Two special round-table discussions will be focused on the world-wide strategic research agenda in the field of nanosafety. Overall, the topics of the conference will address the major directions of research relevant to concerns associated with the environmental, occupational and biomedical exposures to nanomaterials. The conference will create opportunities for participants to present and share experiences, explore new directions and debate topics with experts from across the globe in the field of nanotoxicology.

描述（由申请人提供）： 纳米技术的最新进展彻底改变了生活的各个方面，从工程，半导体，建筑材料到化妆品和纳米医学。独特的物理化学特性与广阔的表面积相结合，使纳米材料的生物学作用及其与细胞，组织和生物流体的相互作用在很大程度上是不可预测的。工程纳米材料的越来越多的使用引起了人们对这些材料无意接触以及对人类健康和环境产生不利影响的担忧。因此，出现了一个新的爆炸性发展的毒理学领域 - 纳米毒理学。纳米毒理学领域的实验性工作正在以指数率进行。尽管如此，仍然缺乏关于纳米材料N人类健康和环境（包括自然生态系统）的潜在影响的数据。填补这一知识的空白将需要科学组织，监管机构和利益相关者之间前所未有的国家和国际协调。拟议的国际会议纳米毒理学-2014是朝这个方向迈出的重要一步。 2014年国际会议纳米毒性学 - 将于2014年4月23日至2014年2月26日在土耳其的安塔利亚举行 - 将聚集在纳米材料毒理学领域的现有研究领导者，从材料，化学家和制造商到分子毒理学家，风险评估专家以及临床科学家以及涉及生物介绍的NANOPARPITYS的临床科学家和转化科学家。自2006年在美国（迈阿密）启动和组织了第一次国际纳米毒理学会议以来，在苏黎世（2008年），爱丁堡（2010年）和北京（2012年）举行了一系列两年的会议。这些会议代表了纳米毒理学领域的主要科学事件，在纳米毒理学领域中，最具创新性和重大突破的结果在新兴学科中得到了战略性传播，并为科学家，纳米材料制造工业，公共卫生，公共卫生官员，公共卫生官员，风险评估/监管问题的代表提供了研究社区。会议的主要目标是为具有不同专业知识领域的研究人员提供跨学科讨论的机会，以了解该领域 化学，生物学，纳米材料的作用和毒性的分子机制，因此为风险评估提供基础，从而促进纳米材料的设计和生产，对人类健康和环境的不利影响最小化。 The topics of the conference are focused on the latest most innovative areas of the exploding discipline of nanotoxicology: nanotoxicology and human toxicology, nano-environmental health and safety, eco-nanotoxicology, dose-response paradigm, molecular mechanisms of nontoxicity, immune responses to nanoparticles, nanomedicine, pharmacokinetics and在包括纳米QSARS，包括纳米QSAR的硅材料建模方法中，纳米材料的纳米材料，系统生物学方法的特定动力学，纳米生物生物界面和纳米材料，暴露情况和风险评估，系统生物学方法，纳米材料，纳米技术风险的监管挑战。会议计划中还将包括有关年轻研究人员的“纳米安全研究方法”的一系列讲座。两个特别的圆桌讨论将集中在纳米安全领域的全球战略研究议程上。总体而言，会议的主题将解决与与纳米材料的环境，职业和生物医学暴露有关的关注有关的研究的主要方向。该会议将为参与者创造机会，与来自纳米毒理学领域的全球专家展示和分享经验，探索新的方向和辩论主题。