Project 1: DWHD, Lifetime Adversity and Reproductive-Aged Women

项目 1：DWHD、终生逆境和育龄妇女

• 批准号: 8895454
• 负责人: Emily Wheeler Harville
• 金额: $ 0.85万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8895454
• 关键词: Address; Adult; Affect; Age; Air Pollution; Anxiety; Birth; Blood specimen; Communities; Data; Disasters; Distress; Economics; Environmental Exposure; Environmental Pollution; Explosion; Exposure to; Fertility; Future Generations; Goals; Health; Human; Hurricane; Institute of Medicine (U.S.); Intervention; Interview; Lead; Low Birth Weight Infant; Mental Depression; Mental Health; Mercury; Monitor; Mothers; Oils; Outcome; Physical environment; Population; Population Study; Pregnancy; Pregnancy Outcome; Pregnant Women; Premature Birth; Psychology; Psychopathology; Recruitment Activity; Research; Risk; Role; Social Environment; Source; Stress; Vulnerable Populations; Woman; Women' s Health; abuse neglect; aged; depressive symptoms; experience; health disparity; improved; innovation; member; men; physical conditioning; pregnant; psychologic; reproductive; resilience; social; social disparities; stressor

The parishes examined by this proposal have seen "five disasters in five years" - Hurricanes Katrina, Rita, Gustav, Ike, and the DWH disaster. The mental and physical health of women of reproductive age is important not only in itself, but for the health of future generations. Previous studies of environmental disasters largely indicate that although the physical effects of environmental disasters are usually the major source of concern, psychological effects of these disasters can be more significant. Women are vulnerable to post-disaster psychopathology, and pregnant women and mothers may be particularly vulnerable. Women who experience stress during their pregnancy and who have depression or other mental health problems are also at increased risk for adverse pregnancy outcomes like low birthweight (LBW) and preterm birth (PTB). In addition, some environmental contaminants, such as lead and air pollution, have been associated with adverse pregnancy outcomes. While it has been proposed that the effects of social and environmental adversity are likely to be cumulative and perpetuate health disparities, this has been little studied. We propose to compare mental and physical health outcomes in women exposed in varying degrees to the DWH disaster. 250 pregnant and non-pregnant women each, from two affected communities, will be recruited over two years, and will be questioned about their experience of the oil spill. Hurricane Katrina, and other adversities. They will also provide blood samples to determine lead and mercury levels. Air pollution data will be collected from monitoring data. Depression and anxiety levels, as well as reproductive choices, will be examined in these women. An additional 1000 pregnant women will be recruited over four years to allow us to examine the effects of the disasters and environmental exposures on birth outcomes. Our specific aims are 1) To determine the effect of the DWH disaster on the mental health of women of reproductive age; 2) To determine the effect of the DWH disaster on reproductive outcomes (reproductive choices, fertility, LBW, PTB); 3) To determine the effect of lifetime social adversity on reproductive outcomes, and 4) To determine how social and environmental adversity interact to affect reproductive outcomes. The proposed research will be innovative in bringing together the research on disaster psychology with stress and pregnancy, examining the role of lifetime social adversities on reproductive outcomes, and examining the interaction between social adversity and environmental contamination.

该提案审查的教区经历了“五年内五次灾难”——卡特里娜飓风、丽塔飓风、古斯塔夫飓风、艾克飓风和 DWH 灾难。育龄妇女的身心健康不仅本身很重要，而且对于子孙后代的健康也很重要。以往对环境灾害的研究很大程度上表明，虽然环境灾害的物理影响通常是人们关注的主要来源，但这些灾害的心理影响可能更为显着。妇女很容易受到灾后精神病理学的影响，孕妇和母亲可能尤其容易受到伤害。在怀孕期间经历压力以及患有抑郁症或其他心理健康问题的女性，出现低出生体重 (LBW) 和早产 (PTB) 等不良妊娠结局的风险也会增加。此外，一些环境污染物，例如铅和空气污染，与不良妊娠结局有关。尽管有人提出，社会和环境逆境的影响可能会累积，并使健康差距永久化，但这种影响微乎其微。 研究过。我们建议比较不同程度遭受 DWH 灾难的女性的心理和身体健康结果。将在两年内招募来自两个受影响社区的各 250 名孕妇和非孕妇，并询问她们在石油泄漏事件中的经历。卡特里娜飓风和其他逆境。他们还将提供血液样本以确定铅和汞的含量。空气污染数据将从监测数据中收集。将对这些女性的抑郁和焦虑水平以及生育选择进行检查。我们将在四年内另外招募 1000 名孕妇，以便我们研究灾难和环境暴露对出生结果的影响。我们的具体目标是 1) 确定 DWH 灾难对育龄妇女心理健康的影响； 2) 确定 DWH 灾难对生殖结果的影响（生殖选择、生育力、LBW、PTB）； 3) 确定一生的社会逆境对生殖结果的影响，以及 4) 确定社会和环境逆境如何相互作用以影响生殖结果。拟议的研究将具有创新性，它将灾难心理学与压力和怀孕的研究结合起来，研究终生社会逆境对生殖结果的作用，并研究社会逆境与环境污染之间的相互作用。