Project 1: DWHD, Lifetime Adversity and Reproductive-Aged Women

项目 1：DWHD、终生逆境和育龄妇女

• 批准号: 8239654
• 负责人: Emily Wheeler Harville
• 金额: $ 30.58万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-27 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8239654
• 关键词: Address; Adult; Affect; Age; Air Pollution; Anxiety; Birth; Blood specimen; Communities; Data; Disasters; Distress; Economics; Environmental Exposure; Environmental Pollution; Explosion; Exposure to; Fertility; Future Generations; Goals; Health; Human; Hurricane; Institute of Medicine (U.S.); Intervention; Interview; Lead; Low Birth Weight Infant; Mental Depression; Mental Health; Mercury; Monitor; Mothers; Oils; Outcome; Physical environment; Population; Population Study; Pregnancy; Pregnancy Outcome; Pregnant Women; Premature Birth; Psychology; Psychopathology; Recruitment Activity; Research; Risk; Role; Social Environment; Source; Stress; Vulnerable Populations; Woman; Women' s Health; abuse neglect; aged; depressive symptoms; experience; health disparity; improved; innovation; member; men; physical conditioning; pregnant; psychologic; reproductive; resilience; social; social disparities; stressor

The parishes examined by this proposal have seen "five disasters in five years" - Hurricanes Katrina, Rita, Gustav, Ike, and the DWH disaster. The mental and physical health of women of reproductive age is important not only in itself, but for the health of future generations. Previous studies of environmental disasters largely indicate that although the physical effects of environmental disasters are usually the major source of concern, psychological effects of these disasters can be more significant. Women are vulnerable to post-disaster psychopathology, and pregnant women and mothers may be particularly vulnerable. Women who experience stress during their pregnancy and who have depression or other mental health problems are also at increased risk for adverse pregnancy outcomes like low birthweight (LBW) and preterm birth (PTB). In addition, some environmental contaminants, such as lead and air pollution, have been associated with adverse pregnancy outcomes. While it has been proposed that the effects of social and environmental adversity are likely to be cumulative and perpetuate health disparities, this has been little studied. We propose to compare mental and physical health outcomes in women exposed in varying degrees to the DWH disaster. 250 pregnant and non-pregnant women each, from two affected communities, will be recruited over two years, and will be questioned about their experience of the oil spill. Hurricane Katrina, and other adversities. They will also provide blood samples to determine lead and mercury levels. Air pollution data will be collected from monitoring data. Depression and anxiety levels, as well as reproductive choices, will be examined in these women. An additional 1000 pregnant women will be recruited over four years to allow us to examine the effects of the disasters and environmental exposures on birth outcomes. Our specific aims are 1) To determine the effect of the DWH disaster on the mental health of women of reproductive age; 2) To determine the effect of the DWH disaster on reproductive outcomes (reproductive choices, fertility, LBW, PTB); 3) To determine the effect of lifetime social adversity on reproductive outcomes, and 4) To determine how social and environmental adversity interact to affect reproductive outcomes. The proposed research will be innovative in bringing together the research on disaster psychology with stress and pregnancy, examining the role of lifetime social adversities on reproductive outcomes, and examining the interaction between social adversity and environmental contamination.

该提议所检查的教区已经看到了“五年来五年灾难” - 卡特里娜飓风，丽塔，古斯塔夫，艾克和DWH灾难。生殖年龄的妇女的身心健康不仅重要，而且对于子孙后代的健康而言很重要。先前对环境灾难的研究在很大程度上表明，尽管环境灾难的身体影响通常是关注的主要来源，但这些灾难的心理影响可能会更加重要。妇女容易患疾病后的心理病理学，孕妇和母亲可能特别容易受到伤害。 怀孕期间承受压力，患有抑郁症或其他心理健康问题的妇女也有增加怀孕结果的风险，例如低出生体重（LBW）和早产（PTB）。此外，某些环境污染物（例如铅和空气污染）与不良妊娠结局有关。虽然已经提出，社会和环境逆境的影响可能是累积性的，并且会使健康差异持续下去，但这几乎没有 研究。我们建议将在不同程度上暴露于DWH灾难的妇女中的身心健康结果进行比较。 250名来自两个受影响社区的孕妇和非怀孕妇女将在两年内招募，并将质疑她们对漏油事件的经历。卡特里娜飓风和其他逆境。他们还将提供血液样本以确定铅和汞水平。 空气污染数据将从监视数据中收集。这些女性将检查抑郁和焦虑水平以及生殖选择。在四年内将招募另外1000名孕妇，以使我们能够检查灾难和环境暴露对出生结果的影响。我们的具体目的是1）确定DWH灾难对生殖年龄妇女的心理健康的影响； 2）确定DWH灾难对生殖结果的影响（生殖选择，生育能力，LBW，PTB）； 3）确定终身社会逆境对生殖结果的影响，以及4）确定社会和环境逆境如何相互作用以影响生殖结果。拟议的研究将具有创新性，可以使关于灾难心理学的研究和怀孕，研究终生社会逆境对生殖结果的作用，并研究社会逆境与环境污染之间的相互作用。