Structural and Computational Biophysics Training Program

结构和计算生物物理学培训计划

• 批准号: 8691895
• 负责人: DOUGLAS S. LYLES
• 金额: $ 18.05万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8691895
• 关键词: Biophysics; Training Programs

DESCRIPTION (provided by applicant): This proposal seeks funding for an NRSA Institutional Predoctoral Training Grant from the Molecular Biophysics Program of the National Institute for General Medical Sciences (NIGMS). This grant will support predoctoral training in Structural and Computational Biophysics (SCB) leading to a Ph.D. degree at Wake Forest University. The goal of the SCB Training Program is to bridge the gap in training between biomedical sciences and more basic quantitative sciences. The SCB training faculty is highly collaborative across departmental lines, and includes faculty members from Physics, Chemistry, Biochemistry, and Molecular Medicine. Students are trained in structural biology (X-ray and NMR), computational biology, proteomics, and biophysics. The major scientific themes of the SCB Training Program include the overlapping areas of DNA damage and repair, redox biology, and molecular signaling. The Program has a flexible curriculum that is designed to meet the individual needs of the students in the program, and includes a well-developed system of interdisciplinary seminars and tutorials to promote interaction among members of the program. In addition to the SCB training faculty, who will serve as mentors for Ph.D. students, we also have a well-established network of resource faculty that contribute to the training of graduate students through educational innovation, direction of Core Laboratories that are central to training in structural biology and biophysics, and provision of career advice and networking with biotechnology industries. We offer specific training in skills for a wide variety of potential careers for our Ph.D. graduates, including academic careers, careers in the biotechnology and pharmaceutical industries, as well as careers in the intellectual property arena. We have developed a pipeline in which Masters' degree students in Physics, Mathematics and Computer Science can obtain a certificate in Structural and Computational Biophysics that provides a transition into Ph.D. training in our program. Similarly, we have an excellent track record of engaging Ph.D. students in biological sciences in structural and computational research. We have an active program of recruiting students from ethnic groups that are underrepresented in science into our training program. Funding is requested for 4 predoctoral positions out of the steady state level of 25-30 students in the laboratories of the training faculty. These positions will be used to support students in the second year or beyond, at which time it will be apparent that their dissertation research is consistent with the goals of the Program. Support will be for a maximum of two years, after which the students will be supported by the research funding of their advisors or their own individual fellowships.

描述（由申请人提供）：该提案寻求资助NRSA机构的培训培训赠款，该培训资助了美国国家一般医学科学研究所（NIGMS）的分子生物物理学计划。该赠款将支持结构和计算生物物理学（SCB）中的专用培训，导致博士学位。维克森林大学的学位。 SCB培训计划的目标是弥合生物医学科学和更基本的定量科学之间训练的差距。 SCB培训教师在部门之间是高度合作的，包括物理，化学，生物化学和分子医学的教职员工。学生接受了结构生物学（X射线和NMR），计算生物学，蛋白质组学和生物物理学的培训。 SCB培训计划的主要科学主题包括DNA损伤和修复的重叠区域，氧化还原生物学和分子信号传导。该计划具有灵活的课程，旨在满足计划中学生的个人需求，并包括一个完善的跨学科研讨会和教程系统，以促进该计划成员之间的互动。除了SCB培训学院，他还将担任博士学位的导师。学生，我们还拥有一个完善的资源教师网络，通过教育创新，核心实验室的方向为研究生培训，这是培训结构生物学和生物物理学的核心，以及提供职业建议以及与生物技术工业的建立联系。我们为我们的博士学位提供各种潜在职业的技能培训。毕业生，包括学术职业，生物技术和制药行业的职业以及知识产权领域的职业。我们已经开发了一条管道，其中硕士学位的物理学，数学和计算机科学的学生可以获得结构和计算生物物理学的证书，该证书将过渡到博士学位。我们计划的培训。同样，我们在引人入胜的博士学位方面有着出色的记录。结构和计算研究生物科学的学生。我们有一个积极的计划，将来自族裔群体的学生招募，而这些学生在我们的培训计划中的招募人数不足。资金被要求从培训学院实验室的25-30名学生的稳态级别中占据4个职位。这些职位将用于在第二年或以后为学生提供支持，此时显然他们的论文研究与计划的目标一致。支持将最多两年，然后学生的顾问或自己的个人奖学金的研究资助将为学生提供支持。