genomics

基因组学

基本信息

批准号：
8486522
负责人：
STEVEN Terry ROSEN
金额：
$ 18.52万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-06 至 2013-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8486522
关键词：
Area Arts Base Sequence Bioinformatics Biotechnology Blood specimen Budgets Cancer Biology Cancer Center Charge Chicago Collaborations Communities Comprehensive Cancer Center DNA DNA Sequence Data Analyses Disease Early Diagnosis Educational workshop Equilibrium Gene Chips Gene Expression Profiling Genes Genomics Genotype Goals Grant Health Hospitals Housing Illinois Institution Italy Joints Knowledge Laboratories Molecular Profiling National Center for Research Resources Nucleic acid sequencing Pathology Peer Review Grants Price Proteomics Protocols documentation Research Research Personnel Resource Sharing Resources Running SNP genotyping Services System Technology Time Training United States National Institutes of Health Universities Wages base cancer prevention cost cost effective density improved instrument instrumentation medical schools member new technology novel therapeutics operation programs

项目摘要

The Genomics core is a new shared resource facility that brings together into one core, the capabilities of Microarray and Genotyping cores along with the DMA sequencing services previously offered by the Northwestern Biotechnology Laboratory. The facility provides the Robert H. Lurie Comprehensive Cancer Center members, NU researchers, and external users access to gene expression profiling using three platforms; genotyping and SNP analysis using three different technologies; automated high-throughput DNA extraction and DNA sequencing services. This consolidation produces a more efficient and cost effective operation. The core is staffed by the director, 5 technicians and a financial assistant. The core houses 8 major instruments, including a Centra Systems AUTOPURE LS, Illumina BeadChip 500GXDW system, Affymetrix GeneChip instrument system, ABI 7900HT, 400XL ScanArray, MicroGridll, ABI 3130x1 and an 3730 DNA analyzer. The Genomics core collaborates closely with the bioinformatics core and plans to increase its collaboration with pathology core as it consolidates its services into this new operation. In addition, the genomics core will continue sponsoring educational talks and workshops to help maintain a high level of knowledge amongst Cancer Center investigators regarding state-of-the-art genomics research technologies to help facilitate their research.

基因组学核心是一种新的共享资源设施，将其汇集成为一个核心，即微阵列和基因分型核以及先前由DMA测序服务西北生物技术实验室。该设施为Robert H. Lurie综合癌症提供了中心成员，NU研究人员和外部用户使用三个平台；使用三种不同技术的基因分型和SNP分析；自动高通量DNA 提取和DNA测序服务。这种合并产生了更有效和更具成本效益的手术。核心由董事，5位技术人员和财务助理组成。核心房屋8 主要仪器，包括Centra系统自动LS，Illumina Beadchip 500GXDW系统， Affymetrix Genechip仪器系统，ABI 7900HT，400XL Scanarray，Microgridll，ABI 3130x1和A 3730 DNA分析仪。基因组学核心与生物信息学核心紧密合作，并计划将其与病理核心的协作增加，因为它将其服务巩固到这项新操作中。在此外，基因组学核心将继续赞助教育演讲和讲习班，以帮助维持关于最先进的基因组学研究的癌症中心研究人员之间的高知识帮助促进他们的研究的技术。