Cancer Center Support Grant

癌症中心支持补助金

• 批准号: 8723445
• 负责人: MARK A ISRAEL
• 金额: $ 5万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-04 至 2014-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8723445
• 关键词: Bioinformatics; Biometry; Cancer Center Support Grant; Cancer Control; Chemoprevention; Clinical Pharmacology; Clinical Research; Collaborations; Development; Evaluation; Faculty; Flow Cytometry; Funding; Genetic; Genomics; Growth; Immunologic Monitoring; Immunology; Institution; Interdisciplinary Study; Knowledge; Leadership; Maintenance; Malignant Neoplasms; Medical center; Methodology; Mission; Molecular; Molecular Biology; Monitor; Norris Cotton Cancer Center; Parents; Pathology; Pilot Projects; Preventive; Preventive Intervention; Proteomics; Protocols documentation; Radiobiology; Recruitment Activity; Request for Applications; Research; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Scientist; Secure; Services; Technology; Therapeutic; Therapeutic Human Experimentation; Transgenic Organisms; Translating; anticancer research; base; cancer care; cancer epidemiology; cancer imaging; cancer immunotherapy; cellular imaging; innovation; medical schools; new technology; population based; prevent; programs; research facility

DESCRIPTION (provided by applicant): Dartmouth's Norris Cotton Cancer Center (NCCC) submits this competitive renewal application for NCI Cancer Center Support Grant funding for Years 31-35. NCCC is a matrix Center at Dartmouth-Hitchcock Medical Center (DHMC), organized as an interdepartmental component of Dartmouth Medical School and DHMC, with overall responsibility for cancer research, cancer care, and educational and service activities in cancer. NCCC is dedicated to developing strategies to prevent and cure cancer through pioneering interdisciplinary research and translate new knowledge into meaningful preventive and therapeutic approaches. The past five years have been distinguished by significant accomplishments: With the support of its parent institutions, NCCC has taken advantage of its outstanding research facilities to support the growth of its cancer research enterprise, while moving aggressively to a more translational focus on both population-based preventive interventions and clinically based therapeutic research. Over the past funding period, NCCC has (1) strengthened Senior Leadership of the Center; (2) recruited outstanding faculty to strategic priorities; (3) enhanced the infrastructure for research; (4) secured enhanced institutional support; and (5) increased philanthropic resources dedicated to the cancer enterprise. NCCC pursues its mission by promoting collaboration among its 126 scientists and 6 Research Programs, and by facilitating their research efforts through support from 12 Shared Resources. NCCC Research Programs are focused in Cancer Epidemiology/ Chemoprevention, Cancer Control, Molecular Therapeutics, Cancer Mechanisms, Immunology/Cancer Immunotherapy, and Cancer Imaging/ Radiobiology. NCCC Shared Resources provide technology and expertise in Bioinformatics, Biostatistics, Clinical Pharmacology, Flow Cytometry/Cell Imaging, Genomics, Immune Monitoring, Molecular Biology, Pathology, Proteomics, Transgenics/Genetic Constructs, and the Office of Clinical Research. NCCC provides developmental funds to support the initial research efforts of new investigators, innovative and collaborative pilot projects, shared resources, and new technology/methodology. Current total funding for NCCC programs of $54.7M includes $26.5M in NCI-sponsored projects. This application requests continuation of our CCSG to provide partial support for these developmental efforts and for the leadership, administrative, planning and evaluation, shared resources, protocol-specific research, protocol review and monitoring, and other components that are crucial to the maintenance of a coordinated and interactive interdisciplinary program in cancer research.

描述（由申请人提供）：达特茅斯的诺里斯棉花癌中心（NCCC）向NCI癌症中心支持拨款资金31 - 35年提交了竞争性更新申请。 NCCC是达特茅斯 - 希区柯克医学中心（DHMC）的基质中心，该中心是达特茅斯医学院和DHMC的部门间成分，对癌症研究，癌症护理以及癌症的教育和服务活动的总体责任。 NCCC致力于通过开拓跨学科研究来制定预防和治愈癌症的策略，并将新知识转化为有意义的预防和治疗方法。在过去的五年中，NCCC在其母公司的支持下，在其母公司的支持下，利用其出色的研究设施来支持其癌症研究企业的发展，同时积极地将基于人群的预防干预和基于临床治疗的研究更加转化。在过去的资金期间，NCCC（1）加强了该中心的高级领导； （2）招募了杰出的教职员工； （3）增强了研究基础设施； （4）获得了增强的机构支持； （5）增加致力于癌症企业的慈善资源。 NCCC通过促进126名科学家和6个研究计划的合作来追求其使命，并通过12个共享资源的支持来促进他们的研究工作。 NCCC研究计划集中在癌症流行病学/化学预防，癌症控制，分子疗法，癌症机制，免疫学/癌症免疫疗法以及癌症成像/放射生物学。 NCCC共享资源提供了生物信息学，生物统计学，临床药理学，流式细胞术/细胞成像，基因组学，免疫监测，分子生物学，病理学，蛋白质组学，转基因/遗传结构以及临床研究办公室的技术和专业知识。 NCCC提供发展基金，以支持新研究人员，创新和协作试点项目，共享资源和新技术/方法的初步研究工作。 NCCC计划的当前总资金为5470万美元，包括2650万美元的NCI赞助项目。该应用程序要求继续我们的CCSG为这些发展工作以及为领导，行政，计划和评估，共享资源，特定于协议的研究，协议审查和监测以及其他对维持癌症研究中协调和交互式互动式跨学科计划至关重要的组件提供部分支持。